Operculectomy Preceding a Mucoepidermoid Carcinoma Development: Case Report
We present the case of an 18‐year‐old female patient with a history of multiple operculectomies that preceded the development of mucoepidermoid carcinoma in the retromolar region. Mucoepidermoid carcinoma is a malignant glandular epithelial neoplasm characterized by mucous, intermediate and epidermoid cells.
Torres Urbina Claudia Araceli +5 more
wiley +1 more source
The Abnormal Expression of B7‐H4 Is Associated With the Pathogenesis of Autoimmune Thyroid Diseases
Background B7‐H4 is an immunosuppressive molecule extensively studied in tumor diseases and is also of interest in some autoimmune diseases. However, the relationship between B7‐H4 and autoimmune thyroid diseases (AITDs) has not been explored. Objective To investigate the B7‐H4 expression in different tissues of patients with different subtypes of ...
Yuqing Wu +9 more
wiley +1 more source
The vaginal microbiota plays a crucial role in mucosal immunity and defense against pathogens. Disruption of this balance by Candida albicans exosomes (CAE) upregulates virulence‐related SAP1–10 genes and induces inflammation. In a rat model, treatment with Morus alba (MA) extract and Lactobacillus rhamnosus (LR) demonstrated selective suppression of ...
Mahmut Ucar +8 more
wiley +1 more source
Tumor Cell Plasticity in Cancer: Signaling Pathways and Pharmaceutical Interventions
Cell plasticity refers to a dynamic program through which cells reprogram their phenotype, acquiring new histologic and molecular characteristics. Recognized as a hallmark of cancer, cellular plasticity plays a critical role in tumor evolution.
Shangwei Sun +7 more
wiley +1 more source
Diagnosis and Management of Multiple Endocrine Neoplasia Type 1 (MEN1) [PDF]
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominantly inherited disorder, characterised by the occurrence of tumours of the parathyroid glands, the pancreatic islets, the pituitary gland, the adrenal glands and neuroendocrine carcinoid ...
Dreijerink, Koen M.A., Lips, Cees J.M.
core +2 more sources
Transfer of Aging: Implications for Pediatric Solid Organ Transplantation
ABSTRACT Solid organ transplantation (SOT) is a life‐saving intervention for pediatric patients with end‐stage organ failure. Due to the limited availability of pediatric donor organs, organs from older donors are frequently utilized, increasing the risk of age‐mismatched transplants.
Rosalie Wolff von Gudenberg +14 more
wiley +1 more source
Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. [PDF]
Controversy exists regarding the potential regenerative influences of incretin therapy on pancreatic β-cells versus possible adverse pancreatic proliferative effects.
Atkinson, Mark +5 more
core +2 more sources
Exploring the interdependencies of research funders in the UK [PDF]
Investment in medical research is vital to the continuing improvement of the UK's health and wealth. It is through research that we expand our understanding of disease and develop new treatments for patients.
Crane, P +13 more
core +1 more source
G Protein‐Coupled Receptor Signaling: Implications and Therapeutic Development Advances in Cancers
G protein‐coupled receptors (GPCRs) are the dynamic protein family in the human genome. GPCR dysregulation aids in the advancement of cancer through increased migration, survival, and proliferation. Novel treatments that target GPCR signaling include orthosteric ligands, biased receptor mutants, PROTACs, and antibody–drug conjugates.
Inamu Rashid Khan +6 more
wiley +1 more source
Validation of four candidate pancreatic cancer serological biomarkers that improve the performance of CA19.9 [PDF]
Background The identification of new serum biomarkers with high sensitivity and specificity is an important priority in pancreatic cancer research.
Blasutig, Ivan M +8 more
core +2 more sources

