Results 21 to 30 of about 6,187 (188)

Glycometabolic Alterations in Secondary Adrenal Insufficiency: Does Replacement Therapy Play a Role? [PDF]

, 2018
Secondary adrenal insufficiency (SAI) is a potentially life-threatening endocrine disorder due to an impairment of corticotropin (ACTH) secretion from any process affecting the hypothalamus or pituitary gland.
Gianfrilli, Daniele, Graziadio, Chiara, Hasenmajer, Valeria, Isidori, Andrea M., Sbardella, Emilia, Venneri, Mary A.   +5 more
core   +2 more sources

Somatostatin receptor scintigraphy: Its value in tumor localization in patients with Cushing's syndrome caused by ectopic corticotropin or corticotropin-releasing hormone secretion [PDF]

, 1994
purpose: To assess the feasibility of somatostatin receptor scintigraphy for patients with Cushing's syndrome caused by tumors secreting ectopic corticotropin or corticotropin-releasing hormone (CRH).
Bruining, H.A. (Hajo), Herder, W.W. (Wouter) de, Hofland, L.J. (Leo), Kreniming, E.P. (Eric), Kwekkeboom, D.J. (Dirk Jan), Lamberts, S.W.J. (Steven), Malchoff, C.D. (Carl), Nobels, F.R.E. (Frank), Oei, H.Y. (H.), Pols, H.A.P. (Huib), Reubi, J.-C. (Jean-Claude)   +10 more
core   +1 more source

The pathophysiological consequences of somatostatin receptor internalization and resistance [PDF]

, 2003
Somatostatin receptors expressed on tumor cells form the rationale for somatostatin analog treatment of patients with somatostatin receptor-positive neuroendocrine tumors.
Hofland, L.J. (Leo), Lamberts, S.W.J. (Steven)   +1 more
core   +3 more sources

Combined biological therapy with lanreotide autogel and cabergoline in the treatment of MEN-1-related insulinomas. [PDF]

, 2014
Multiple endocrine neoplasia type 1 (MEN1) is a hereditary syndrome associated with the development of many endocrine tumors, involving mainly pituitary, parathyroids, pancreas, although a proliferative state interests all neuroendocrine system.
Camera, L, Carratù, A, Colao, A, de Luca di Roseto, C, Del Prete, M, Di Somma, C, Faggiano, A., Marciello, F, Marotta, V, Ramundo, V   +9 more
core   +1 more source

Innate Lymphoid Cells in Tissue Homeostasis and Diseases

MedComm, Volume 7, Issue 5, May 2026.
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan, Heyang Sun, Chenning Li, Qianya Hong, Shuainan Zhu, Ying Yu, Hao Zhang, Kefang Guo   +7 more
wiley   +1 more source

Increased prevalence of pancreatic neuroendocrine microadenomas in patients with intraductal papillary mucinous neoplasms – yet another example of exocrine-neuroendocrine interaction?

Nowotwory
INTRODUCTION: Intraductal papillary mucinous neoplasms (IPMN) and neuroendocrine tumours (NET) may develop simultaneously in the pancreas. Neuroendocrine microadenomas (NMA) are precursor lesions for NET.
Łukasz Liszka
doaj   +1 more source

Pancreatic Neuroendocrine Tumor Leading to a Diagnosis of Multiple Endocrine Neoplasia Type 1

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Pancreatic neuroendocrine neoplasms are rare but occasionally encountered. They are generally highly vascularized solid tumors, often round in shape with clear boundaries, defined contours, and a homogeneous internal structure. However, they can also present with atypical features, such as cystic degeneration, hemorrhage, calcification, and ...
Noriyuki Hirakawa, Katsuya Kitamura, Kei Yamamoto, Kenichi Tadokoro, Yasunosuke Akita, Jun Uemura, Fumito Yamanishi, Masakazu Abe, Munehide Nakatsugawa, Takao Itoi   +9 more
wiley   +1 more source

Physiological significance of autocrine orexinergic signaling in extra‐hypothalamic tissues

Physiological Reports, Volume 14, Issue 8, April 2026.
Mechanisms of autocrine orexinergic effects in extra‐hypothalamic tissues. Abstract Orexin‐A and orexin‐B, originally discovered as hypothalamic neuropeptides, have been detected in extra‐hypothalamic tissues together with their receptors (OX1R and OX2R) since the early 2000s.
Jean Claude Hakizimana, Makinde Vincent Olubiyi, Abdullateef Isiaka Alagbonsi   +2 more
wiley   +1 more source

Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure

Advanced Science, Volume 13, Issue 17, 23 March 2026.
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian‐Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao‐Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y. Liu, Beibei Huang, Frank R. Rojas, Parra Cuentas. Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Khaja B. Khan, Wei Lu, Luisa M. Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I. Wistuba, Zhubo Wei, Linghua Wang, Don L. Gibbons, Ken Chen, Alexandre Reuben, Jason M. Schenkel, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang   +34 more
wiley   +1 more source

Insulin-secreting tumors of the islets of Langerhans [PDF]

, 1958
Thesis (M.D.)—Boston ...
Robert Rodman
core