Physiological significance of autocrine orexinergic signaling in extra-hypothalamic tissues. [PDF]
Physiol RepMechanisms of autocrine orexinergic effects in extra‐hypothalamic tissues. Abstract Orexin‐A and orexin‐B, originally discovered as hypothalamic neuropeptides, have been detected in extra‐hypothalamic tissues together with their receptors (OX1R and OX2R) since the early 2000s.
Hakizimana JC, Olubiyi MV, Alagbonsi AI.
europepmc +2 more sources
Cyclic AMP signalling in pancreatic islets [PDF]
, 2010 Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Pyne, Nigel J. +2 more
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Unveiling the Invisible: A Case of Canine Diffuse Microscopic Pancreatic Adenocarcinoma With Normal Imaging and Gross Appearance of the Pancreas Complicated by Sterile Peritonitis and Disseminated Intravascular Coagulation. [PDF]
Vet Med SciThis case report describes an atypical presentation of diffuse microscopic pancreatic adenocarcinoma in an 11‐year‐old male neutered Shetland Sheepdog, which was not detectable on advanced diagnostic imaging or during exploratory laparotomy. Despite the absence of visible pancreatic abnormalities, histopathology confirmed malignant infiltration ...
Chan HM +7 more
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Lesió i protecció de les cèl·lules beta en el trasplantament d'illots pancreàtics [PDF]
, 2007 [cat] El trasplantament d'illots pancreàtics pot ser una bona teràpia per els malalts amb diabetis mellitus de tipus 1, però hi ha alguns problemes que cal solventar abans que sigui un tractament estès.
Montolio Rusiñol, Marta
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Human monoclonal islet specific autoantibodies share features of islet cell and 64 kDa antibodies [PDF]
, 1993 The first human monoclonal islet cell antibodies of the IgG class (MICA 1-6) obtained from an individual with Type 1 (insulin-dependent) diabetes mellitus were cytoplasmic islet cell antibodies selected by the indirect immunofluorescence test on pancreas
Brandt, M. +7 more
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Antibodies to the Mr 64,000 (64K) protein in islet cell antibody positive non-diabetic individuals indicate high risk for impaired Beta-cell function [PDF]
, 1992 A prospective study of a normal childhood population identified 44 islet cell antibody positive individuals. These subjects were typed for HLA DR and DQ alleles and investigated for the presence of antibodies to the Mr 64,000 (64K) islet cell antigen ...
Glück, Michael +8 more
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No association between islet cell antibodies and coxsackie B, mumps, rubella and cytomegalovirus antibodies in non-diabetic individuals aged 7–19 years [PDF]
, 1991 Viral antibodies were tested in a cohort of 44 isletcell antibody-positive individuals age 7–19 years, and 44 of their islet cell antibody-negative age and sex-matched classmates selected from a population study of 4208 pupils who had been screened for ...
Muir, Peter +10 more
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A role for the extracellular calcium-sensing receptor in cell-cell communication in pancreatic islets of Langerhans [PDF]
, 2008 Background: The extracellular calcium-sensing receptor (CaR) is expressed in many tissues that are not associated with Ca2+ homeostasis, including the endocrine cells in pancreatic islets of Langerhans.
Persaud, Shanta J.; id_orcid +6 more
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CT and MRI Manifestations of Pancreatic Hemangioma: A Literature Review and a New Case Report. [PDF]
Clin Case RepABSTRACT Pancreatic hemangioma is an extremely rare benign tumor occurring in the pancreas. Preoperative diagnosis is challenging due to its lack of specificity in clinical manifestations and imaging examinations. A pancreatic lesion was found during physical examination of a 54‐year‐old woman who had no symptoms of abdominal discomfort.
Zhang J, Chen J, Zou D, Cao X.
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Cytoplasmic islet cell antibodies recognize distinct islet antigens in IDDM but not in stiff man syndrome [PDF]
, 1993 Cytoplasmic islet cell antibodies are well-established predictive markers of IDDM. Although target molecules of ICA have been suggested to be gangliosides, human monoclonal ICA of the immunoglobulin G class (MICA 1-6) produced from a patient with newly ...
Seißler, Jochen +5 more
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