Results 61 to 70 of about 407,583 (390)
Obesity, diabetes and the risk of colorectal adenoma and cancer
BackgroundColorectal cancer (CRC) is the fourth most commonly diagnosed gastrointestinal (GI) malignancy and the third leading cause of cancer-related death worldwide.
Ghodratollah Soltani+5 more
semanticscholar +1 more source
Parathyroid adenomas are benign neoplasms with a predilection for the inferior parathyroid glands. Genetic mutations identified as contributing to development of parathyroid adenomas include MEN 1 and cyclin D1. Predisposing factors include female gender
Ali Cadili
doaj +1 more source
Long-term use of antibiotics and risk of colorectal adenoma
Objective Recent evidence suggests that antibiotic use, which alters the gut microbiome, is associated with an increased risk of colorectal cancer. However, the association between antibiotic use and risk of colorectal adenoma, the precursor for the ...
Yin Cao+13 more
semanticscholar +1 more source
The role of stereotactic radiosurgery in the multimodal management of growth hormone–secreting pituitary adenomas [PDF]
Growth hormone (GH)–secreting pituitary adenomas represent a common source of GH excess in patients with acromegaly. Whereas surgical extirpation of the culprit lesion is considered first-line treatment, as many as 19% of patients develop recurrent ...
Liu, Charles Y.+2 more
core +1 more source
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
Causal associations of COVID‐19 on neurosurgical diseases risk: a Mendelian randomization study
Many researchers have explored the potential association between one neurosurgical disease and coronavirus disease 2019 (COVID-19), but few systematically analyzed the association and causality between COVID-19 and various neurosurgical diseases.
Lirui Dai+3 more
doaj +1 more source
Does an Analysis of the Pulsatile Secretion Pattern of Adrenocorticotropin and Cortisol Predict the Result of Transsphenoidal Surgery in Cushing’s Disease. [PDF]
The endocrinological, surgical, and histological findings of patients with ACTH-dependent Cushing's disease were correlated with the pulsatile secretion pattern of ACTH and cortisol and the outcome after transsphenoidal pituitary surgery.
Brabant, Georg+5 more
core +1 more source
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti+10 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana+6 more
wiley +1 more source