Results 181 to 190 of about 30,293 (217)

Pathological diagnosis experience and literature review of four cases suspected Lynch-like syndrome. [PDF]

Front Oncol
Cheng B, Liu S, Ding S, Quan L, Liu J, Xu L, Zhao H, Guo J, Sun S.   +8 more
europepmc   +1 more source

Mathematical Modeling Quantifies "Just-Right" APC Inactivation for Colorectal Cancer Initiation. [PDF]

Cancer Res
Brunet Guasch M, Feeley NA, Soriano I, Thorn S, Tomlinson IPM, Nicholson MD, Antal T.   +6 more
europepmc   +1 more source

Familial adenomatous polyposis family with clustering of psychiatric disorders. [PDF]

Jpn J Clin Oncol
Funaki M, Noguchi A, Ishikawa H, Noutomi R, Fukuda K, Shimazu K, Yoshida T, Taguchi D, Shinozaki H, Kodama N, Mishima K, Nanjo H, Takahashi T, Shibata H.   +13 more
europepmc   +1 more source

Educational Case: Familial adenomatous polyposis. [PDF]

Acad Pathol
Ngov DH, Huppmann AR.
europepmc   +1 more source

Population Prevalence of the Major Thyroid Cancer-Associated Syndromes.

J Clin Endocrinol Metab
White SL, Jamil T, Bell C, Fishbein L, Haugen BR, Gignoux CR, Pozdeyev N.   +6 more
europepmc   +1 more source

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Adenomatous polyposis coli proteins and cell adhesion

Current Opinion in Cell Biology, 2004
Adenomatous polyposis coli (APC) is an important tumour suppressor in the mammalian intestinal epithelium. It binds to beta-catenin and its role as a tumour suppressor depends predominantly on its ability to downregulate soluble beta-catenin, a key effector of the Wnt signalling pathway.
Mariann Bienz
exaly   +3 more sources

Non-traditional roles for the Adenomatous Polyposis Coli (APC) tumor suppressor protein

Gene, 2005
The Adenomatous Polyposis Coli (APC) tumor suppressor is a multifunctional protein that is mutated in a majority of colon cancers. The role of APC as an antagonist of the Wnt signaling pathway is well known and it is widely accepted that inappropriate activation of this pathway through loss of APC function contributes to the progression of colon ...
Caroline A, Hanson, Jeffrey R, Miller
exaly   +3 more sources

Adenomatous Polyposis Coli (APC) Protein Expression in Primary and Metastatic Serous Ovarian Carcinoma

International Journal of Surgical Pathology, 2002
The aim of this study was to investigate protein expression of adenomatous polypois coli (APC) in primary and metastatic serous ovarian carcinoma. The expression of 3-catenin and E-cadherin was additionally analyzed. One hundred and thirteen priary (n=56) and metastatic (n=57) lesions were immunohistochemically stained for APC, E-cadherin, and f ...
Ben Davidson
exaly   +3 more sources

Adenomatous Polyposis Coli Protein is Expressed in Alternate Stages of the Ameloblast Life Cycle

Journal of Dental Research, 1998
Mutations of the adenomatous polyposis coli gene protein (APC) are associated with familial polyposis and also sporadic colon adenomas, both preconditions to cancer formation. Some familial polyposis patients also develop Gardner's syndrome, a condition characterized by supernumerary teeth, mandibular osteomas, and other maladies.
Barbara C Sorkin
exaly   +3 more sources

Aspirin augments the expression of Adenomatous Polyposis Coli protein by suppression of IKKβ

Biochemical and Biophysical Research Communications, 2014
Aspirin has been widely used as analgesic, antipyretic and anti-inflammatory medicine for long. In addition to these traditional effects, clinical studies suggest that aspirin can protect against cancer, but its mechanism has not been explored. To unveil it, we identified the proteins up- or down-regulated after incubation with aspirin by using ...
Kaeko Kamei
exaly   +3 more sources