Results 211 to 220 of about 681,334 (361)

Smart Organic–Inorganic Copolymer Nanoparticles Distinguish Between Microglia and Cancer Cells for Synergistic Immunotherapy in Glioma

open access: yesAdvanced Science, EarlyView.
The tumor microenvironment‐responsive nanoagonists are developed using an organic–inorganic copolymer composed of the polymer (PC6AB) and manganous phosphate ionic oligomers (MnP). PC6AB with membranolytic activity selectively interacts with tumor cell membranes to induce immunogenic cell death, while MnP activates the STING pathway in immune cells ...
Shiming Zhang   +14 more
wiley   +1 more source

Placental RTN3L‐dependent ER‐Phagy Contributes to Fetal Testicular Dysplasia Upon Environmental Stress

open access: yesAdvanced Science, EarlyView.
Gestational environmental stress activates ER‐phagy by increasing placental Rtn3l mRNA N6‐methyladenosine modification, further inhibiting placental estradiol synthesis and contributing to fetal testicular dysplasia. This study demonstrates the early prevention and treatment of adult male infertility from the perspective of fetal‐derived diseases ...
Ye‐Xin Luo   +17 more
wiley   +1 more source

The progress and prospects of targeting the adenosine pathway in cancer immunotherapy. [PDF]

open access: yesBiomark Res
Yang Y   +7 more
europepmc   +1 more source

Gastric ulcers and pancreatitis in rats given 2-chloroadenosine or adenosine [PDF]

open access: bronze, 1954
Stephen S. Sternberg   +3 more
openalex   +1 more source

Responsive ROS‐Augmented Prodrug Hybridization Nanoassemblies for Multidimensionally Synergitic Treatment of Hepatocellular Carcinoma in Cascade Assaults

open access: yesAdvanced Science, EarlyView.
This study proposes a novel HCC therapy using CA‐4S2@ES‐Cu nanomedicines to amplify cuproptosis, enhancing chemotherapy and immunotherapy. CA‐4 and ES‐Cu synergistically inhibit tumor growth, induce immune responses, and reverse the immunosuppressive microenvironment, offering an effective multidimensional therapeutic strategy for HCC treatment ...
Yingjie Zeng   +16 more
wiley   +1 more source

Editorial: Purinergic Pharmacology

open access: yesFrontiers in Pharmacology, 2019
Francisco Ciruela   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy