Results 1 to 10 of about 117,365 (258)

Bacillus anthracis edema factor substrate specificity: evidence for new modes of action [PDF]

open access: yes, 2012
Since the isolation of Bacillus anthracis exotoxins in the 1960s, the detrimental activity of edema factor (EF) was considered as adenylyl cyclase activity only.
Agrawal   +94 more
core   +2 more sources

Crosstalk between G-protein and Ca2+ pathways switches intracellular cAMP levels [PDF]

open access: yes, 2001
Cyclic adenosine monophosphate and cyclic guanosine monophosphate are universal intracellular messengers whose concentrations are regulated by molecular networks comprised of different isoforms of the synthases adenylate cyclase or guanylate cyclase and ...
A Dietz   +22 more
core   +2 more sources

The role of cyclic nucleotide on fetal and neonantal erythropoiesis [PDF]

open access: yes, 1974
For the purpose to reveal the changes in stimulatory effect of dibutyryl-cyclic- AMP on erythropoiesis during ontogenetic development, the author studied syntheses of DNA, RNA and protein of erythroid cells in fetal liver, neonatal and adult bone marrows
Tada, Hiroshi
core   +1 more source

3',5'-Cyclic Adenosine Monophosphate- and Ca2+-Calmodulin-Dependent Endogenous Protein Phosphorylation Activity in Membranes of the Bovine Chromaffin Secretory Vesicles: Identification of Two Phosphorylated Components as Tyrosine Hydroxylase and Protein Kinase Regulatory Subunit Type II [PDF]

open access: yes, 1983
: Membranes of the secretory vesicles from bovine adrenal medulla were investigated for the presence of the endogenous protein phosphorylation activity. Seven phosphoprotein bands in the molecular weight range of 250,000 to 30,000 were observed by means ...
Amy C. M.   +27 more
core   +1 more source

Regulation of stanniocalcin-1 secretion by BeWo cells and first trimester human placental tissue from normal pregnancies and those at increased risk of developing preeclampsia. [PDF]

open access: yes, 2020
Stanniocalcin-1 (STC-1) is a multi-functional glycosylated peptide present in the plasma of healthy women postpartum and increased further in pregnancies complicated by preeclampsia. Although the STC-1 gene is expressed by the placenta what regulates its
Asma Khalil   +13 more
core   +1 more source

The T2238C human atrial natriuretic peptide molecular variant and the risk of cardiovascular diseases [PDF]

open access: yes, 2018
Atrial natriuretic peptide (ANP) is a cardiac hormone which plays important functions to maintain cardio-renal homeostasis. The peptide structure is highly conserved among species. However, a few gene variants are known to fall within the human ANP gene.
Bianchi, Franca   +5 more
core   +2 more sources

In Vitro Transcription of the Gal Operon Requires Cyclic Adenosine Monophosphate and Cyclic Adenosine Monophosphate Receptor Protein

open access: yesJournal of Biological Chemistry, 1971
Abstract In a transcription system containing λpgal8 DNA as template and Escherichia coli RNA polymerase, the addition of cyclic adenosine monophosphate receptor protein (CRP) and 3',5'-cyclic AMP causes a 15-fold increase in gal mRNA synthesis. Gal mRNA was measured by hybridizing the [3H]RNA product to the separated strands of λpgal8 DNA after ...
S P, Nisseley   +4 more
openaire   +2 more sources

c-di-AMP: An essential molecule in the signaling pathways that regulate the viability and virulence of gram-positive bacteria [PDF]

open access: yes, 2017
Signal transduction pathways enable organisms to monitor their external environment and adjust gene regulation to appropriately modify their cellular processes.
Cho, Kyu Hong   +2 more
core   +2 more sources

Cyclic AMP signalling in pancreatic islets [PDF]

open access: yes, 2010
Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Furman, Brian   +2 more
core   +1 more source

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