Results 21 to 30 of about 65,630 (160)

Characterization of the taste receptor‐related G‐protein, α‐gustducin, in pancreatic β‐cells

open access: yesJournal of Diabetes Investigation, 2020
Aims/Introduction Taste receptors, T1rs and T2rs, and the taste‐selective G‐protein, α‐gustducin, are expressed outside the taste‐sensing system, such as enteroendocrine L cells.
Haruhide Udagawa   +7 more
doaj   +1 more source

Detection and characterisation of NAD(P)H-diaphorase activity in Dictyostelium discoideum cells (Protozoa)

open access: yesEuropean Journal of Histochemistry, 2012
In Dictyostelium discoideum (D. discoideum), compounds generating nitric oxide (NO) inhibit its aggregation and differentiation without altering cyclic guanosine monophosphate (cGMP) production.
A. Amaroli, M.G. Chessa
doaj   +1 more source

Effects of cyclic nucleotides on midgut infections and maturation of T. b. brucei in G. m. morsitans

open access: yesParasites & Vectors, 2008
Cyclic nucleotide signalling through cyclic adenosine monophosphate (cAMP) is thought to play an important role in the transformation of the long slender (dividing) form to the short-stumpy (arrested) form in the mammalian bloodstream but the role of ...
Maudlin Ian   +2 more
doaj   +1 more source

Liver hydrolysate improves depressive-like behavior in olfactory bulbectomized mice: Involvement of hippocampal neurogenesis through the AMPK/BDNF/CREB pathway

open access: yesJournal of Pharmacological Sciences, 2020
Recently, we has reported that AMPK activator has antidepressant effect. Previous our study suggested that liver hydrolysate (LH) activated adenosine monophosphate-activated protein kinase (AMPK) in periphery.
Osamu Nakagawasai   +8 more
doaj   +1 more source

In Vitro Transcription of the Gal Operon Requires Cyclic Adenosine Monophosphate and Cyclic Adenosine Monophosphate Receptor Protein

open access: yesJournal of Biological Chemistry, 1971
Abstract In a transcription system containing λpgal8 DNA as template and Escherichia coli RNA polymerase, the addition of cyclic adenosine monophosphate receptor protein (CRP) and 3',5'-cyclic AMP causes a 15-fold increase in gal mRNA synthesis. Gal mRNA was measured by hybridizing the [3H]RNA product to the separated strands of λpgal8 DNA after ...
S P, Nisseley   +4 more
openaire   +2 more sources

Extracellular vesicles: another compartment for the second messenger, cyclic adenosine monophosphate

open access: yesAmerican Journal of Physiology - Lung Cellular and Molecular Physiology, 2019
Judy KING   +2 more
exaly   +2 more sources

Vinpocetine is the forthcoming adjuvant agent in the management of COVID-19

open access: yesFuture Science OA, 2022
Vinpocetine (VPN) is an alkaloid derivative of vincamine inhibits phosphodiesterase type 1 that increase cyclic guanosine monophosphate and cyclic adenosine monophosphate. VPN have anti-inflammatory and antioxidant effects with suppression release of pro-
Hayder M Al-kuraishy   +3 more
doaj   +1 more source

Brucella spp. Omp25 Promotes Proteasome-Mediated cGAS Degradation to Attenuate IFN-β Production

open access: yesFrontiers in Microbiology, 2021
Type I interferons (IFN), a family of cytokines widely expressed in various tissues, play important roles in anti-infection immunity. Nevertheless, it is not known whether Brucella spp.
Ruizhen Li   +9 more
doaj   +1 more source

Novel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012

open access: yesMolecules, 2016
Cyclic nucleotide phosphodiesterases (PDEs) are a class of intracellular enzymes that inactivate the secondary messenger molecules, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP).
Susann Schröder   +4 more
doaj   +1 more source

Salidroside Attenuates Hydrogen Peroxide-Induced Cell Damage Through a cAMP-Dependent Pathway

open access: yesMolecules, 2011
Salidroside, a major component of Rhodiola rosea L., has shown various pharmacological functions, including antioxidant effects, but the signal transduction pathway of its antioxidant effects is not very clear.
Xuming Deng   +6 more
doaj   +1 more source

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