Results 221 to 230 of about 734,488 (357)

Inhibition of Retinal AdoRA2a Activity Attenuates Myopia Progression. [PDF]

Invest Ophthalmol Vis Sci
Liu S, Guan Z, Yang X, Li W, Qu W, Zhou Y, Zhao F, Wang Q, Huang F, Chen W, Qu J, Zhou X, Pan M.   +12 more
europepmc   +1 more source

Evaluation of adenosine deaminase/CD26 pathway in the proliferation and esophageal cancer progression

, 2022
Laisa Helena Silva Silveira
openalex   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

Special Issue "Purinergic Signalling in Physiology and Pathophysiology 2.0". [PDF]

Int J Mol Sci
Sluyter R.
europepmc   +1 more source

Intestinal arteriolar responses to mucosal and serosal applications of adenosine analogues. [PDF]

, 1987
Kenneth G. Proctor
openalex   +1 more source

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

Advanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang   +8 more
wiley   +1 more source

Aberrant adenosine A_2A receptor signaling in the choroid plexus drives CSF hypersecretion and ventriculomegaly in hydrocephalus. [PDF]

Nat Commun
Zheng W, Hu L, Yang Y, Li X, Wu J, Chen W, Jiang Y, Chen Y, Wang H, Li S, Feng K, Zheng C, Wang Y, Cunha RA, Lv Z, Chen JF.   +15 more
europepmc   +1 more source

Purine metabolism in cultured endothelial cells [PDF]

, 1980
Gerbes, Alexander L., Gerlach, E., Nees, S., Sperling, Oded, Willershausen, B.   +4 more
core   +1 more source

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

Advanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng, Jia‐Jia Liang, Yun‐Feng Zhan, Wei‐Xun Wu, Wan‐Li Xu, Xiao‐Kun Zhang, Li‐Jun Cai, Fu‐Quan Jiang   +7 more
wiley   +1 more source

CD39⁺PD-1⁺ regulatory T cells in melanoma: key drivers of systemic immunosuppression and prognostic biomarkers. [PDF]

Front Oncol
Qiao G, He H, Wang X.
europepmc   +1 more source