Results 221 to 230 of about 681,334 (361)

HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis

Advanced Science, EarlyView.
Glioblastoma (GBM) growth relies on glutamine synthetase (GS), which is stabilized by histone deacetylase 6 (HDAC6) and deubiquitinated by ubiquitin‐specific peptidase 9, X‐linked (USP9X). HDAC6 promotes GS deacetylation, while USP9X removes its K48‐linked polyubiquitination, enhancing GS stability.
Go Woon Kim, Minhae Cha, Hien Thi My Ong, Jung Yoo, Yu Hyun Jeon, Sang Wu Lee, Soo Yeon Oh, Min‐Jung Kang, Youngsoo Kim, So Hee Kwon   +9 more
wiley   +1 more source

Exploring Treatment Protocol Adherence and Variations in Paroxysmal Supraventricular Tachycardia in the Emergency Department: A Multi-Center Cohort Study. [PDF]

Med Sci (Basel)
Ku K, Healy J, Lee CA, Khan M, Chao KD, Hassan S, Tzeng CT, Hsieh YL, Shedd A, Bhakta T, Hassani D, Chou EH.   +11 more
europepmc   +1 more source

CHEMICAL FRACTIONATION OF ADENYLIC ACIDS a AND b AND THEIR ENZYMIC CONVERSION TO ADENOSINE

, 1952
Peter Reichard, Yasuo Takenaka, Hubert S. Loring   +2 more
openalex   +1 more source

TCMD: A High‐Throughput and Rapid Method for Screening Antimicrobial Ingredients from Renewable Bio‐Based Resources

Advanced Science, EarlyView.
This study develops a strategy to screen the active compounds from bio‐mixtures via combining transcriptomic profiling and molecular docking. The proposed method demonstrates 100% correction in three different biobased mixtures and is 3–20 times faster than traditional approaches.
Yongdong Xu, Yueyao Wang, Yongming Chen, Yunxia Wang, Shicheng Zhang, Gang Luo, Fuhao Cui, Taisheng Du, Zhidan Liu   +8 more
wiley   +1 more source

Semaglutide and adenosine alleviate obesity-induced kidney injury, with observed modulation of the Txnip/NLRP3 pathway. [PDF]

Diabetol Metab Syndr
Wang S, Pan X, Liang R, Chen S.
europepmc   +1 more source

ENZYMATIC FRACTIONATION OF ADENOSINE PYROPHOSPHATES IN HUMAN BLOOD

, 1954
Bruce Mackler, Peter Foris, George M. Guest   +2 more
openalex   +1 more source

Splitting of Adenosine Triphosphate by Myosin [PDF]

, 1946
I Banga
openalex   +1 more source

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

Advanced Science, EarlyView.
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan, Jingyi Qi, Yi Xia, Chang Fan, Teng Xu, Xu Zhang, Jiaxin Shi, Chenxuan Wang, Yitong Cheng, Dongyuan Zhang, Rong Liu, Yinhua Zhu, Changchang Cao, Dekui Jin, Peng An, Yongting Luo, Junjie Luo   +16 more
wiley   +1 more source

Exploring the Sensitivity of Peripheral ADA Levels Measurement in Establishing Psychosis Susceptibility. [PDF]

J Mol Neurosci
Kizilpinar SC, Atak-Akkus FB, Dogan O, Colak B, Aydemir MC.   +4 more
europepmc   +1 more source

Gasdermin D‐Mediated Pyroptosis Exerts Two Opposite Effects of Resisting Enzymatic Digestion and Expanding Inflammatory Response in Acute Pancreatitis

Advanced Science, EarlyView.
Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu, Ning Liang, Chen Wu, Zhaoyan Qiu, Qian Huang, Xiaolong Wei, Shurong Zhang, Shuanghong Lei, Tao Yang, Gang Wang, Qian Wang   +10 more
wiley   +1 more source