Results 311 to 320 of about 570,134 (357)

The adenosine pathway in immuno-oncology

Nature Reviews Clinical Oncology, 2020
Bertrand Allard, Laurence Buisseret, John Stagg   +2 more
exaly   +2 more sources

Targeting immunosuppressive adenosine in cancer

Nature Reviews Cancer, 2017
Dipti Vijayan, Michele W L Teng, Mark J Smyth   +2 more
exaly   +2 more sources

Structure of the adenosine-bound human adenosine A1 receptor–Gi complex

Nature, 2018
David M Thal, Yi-Lynn Liang, Sebastian George Barton Furness   +2 more
exaly   +2 more sources

Immunity, inflammation and cancer: a leading role for adenosine

Nature Reviews Cancer, 2013
Luca Antonioli, Corrado Blandizzi, Pal Pacher   +2 more
exaly   +2 more sources

Adenosine and Adenosine Receptors [PDF]

American Journal of Respiratory Cell and Molecular Biology, 1990
In the last decade, there has been renewed interest in extracellular signaling by adenosine and adenine nucleotides. The potent cardiovascular effects of these agents were originally described by Drury and Szent-Gy6rgyi in 1929 (1). This report was followed by a flurry of interest in the use of adenosine as an antihypertensive agent, which subsided ...
openaire   +2 more sources

Regulation of sleep homeostasis mediator adenosine by basal forebrain glutamatergic neurons

Science, 2020
Sleep and basal forebrain activity Different patterns of neural activity in the brain control the sleep-wake cycle. However, how this activity contributes to sleep homeostasis remains largely unknown.
Wanling Peng, Zhaofa Wu, Kun Song, Siyu Zhang, Yulong Li, Min Xu   +5 more
semanticscholar   +1 more source

Adenosine and adenosine receptors in colorectal cancer

International Immunopharmacology, 2020
CD39 (nucleoside triphosphate diphosphohydrolase) and Ecto-5-nucleotidase (CD73) have been recognized as important factors mediating various pathological and physiological responses in the tumor microenvironment. Elevated expression of CD73 and CD39 is correlated with the over-production of adenosine in the tumor region.
A.V. Sevbitov, Makwan Peydaveisi, Ali Masjedi, Farnaz Hajizadeh, Sima Heydarzedeh Asl, Farhad Jadidi-Niaragh, Ghasem Ghalamfarsa, Fariba Karoon Kiani   +7 more
openaire   +2 more sources

Interstitial adenosine with dipyridamole: effect of adenosine receptor blockade and adenosine deaminase

American Journal of Physiology-Heart and Circulatory Physiology, 1992
Dipyridamole is proposed to increase coronary blood flow (CBF) by inhibition of adenosine uptake into cells, resulting in an increase in interstitial fluid (ISF) adenosine and an adenosine-mediated vasodilation. The purpose of this study was to determine the changes in CBF and ISF adenosine, inosine, and hypoxanthine during dipyridamole infusion in ...
D. G. L. Van Wylen, T. Wang, R. M. Mentzer   +2 more
openaire   +3 more sources

Is adenosine deaminase involved in adenosine transport?

Medical Hypotheses, 1990
The hypothesis that adenosine metabolizing enzymes may have a key role in the transport of adenosine is discussed. The enhancement of adenosine transport by inhibitors of adenosine deaminase (the enzyme which deaminates adenosine to inosine) and the ecto-localization of adenosine deaminase suggest a contribution of the enzyme in taking up nucleosides ...
Josep J. Centelles, Rafael Franco
openaire   +3 more sources