Results 321 to 330 of about 869,856 (392)

Production of Adenosine Triphosphate in Normal Cells and Sporulation Mutants of Bacillus subtilis

open access: hybrid, 1969
Walther Klofat   +3 more
openalex   +1 more source

API5 Phosphorylation Promotes Antiviral Immunity by Inhibiting Degradation of Cytosolic RNA Sensor RLRs

open access: yesAdvanced Science, EarlyView.
Ubiquitin‐mediated selective autophagy plays a critical role in antiviral innate immunity. The study shows that upon RNA virus infection, cytoplasmic API5 undergoes SRPK1‐dependent phosphorylation at S464, which in turn suppresses p62 K141 ubiquitination‐dependent autophagy.
Tingjuan Deng   +10 more
wiley   +1 more source

Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice

open access: yesAdvanced Science, EarlyView.
Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu   +14 more
wiley   +1 more source

Inhibition of ENT1 relieves intracellular adenosine-mediated T cell suppression in cancer. [PDF]

open access: yesNat Immunol
Sanders TJ   +19 more
europepmc   +1 more source

Metabolic Programming Drives Protective and Inflammatory Monocyte Fates in Viral Encephalitis

open access: yesAdvanced Science, EarlyView.
Bone marrow monocytes infiltrate the West Nile virus‐infected brain and differentiate into HIF1‐α⁺ monocyte‐derived cells (MCs) that diverge into protective, antigen‐presenting or inflammatory, iNOS⁺ MCs with distinct metabolic programs and functions.
Claire L. Wishart   +4 more
wiley   +1 more source

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