Results 331 to 340 of about 681,334 (361)

Targeting the Adenosine-Mediated Metabolic Immune Checkpoint with Engineered Probiotic for Enhanced Chemo-Immunotherapy. [PDF]

open access: yesAdv Sci (Weinh)
Wang J   +11 more
europepmc   +1 more source

Current and Emerging Insights into the Causes, Immunopathogenesis, and Treatment of Cutaneous Squamous Cell Carcinoma. [PDF]

open access: yesCancers (Basel)
Anderson R   +6 more
europepmc   +1 more source

Functional profiling reveals a non-enzymatic role of NUDT5 in repressing purinede novosynthesis

open access: yes
Lin JG   +27 more
europepmc   +1 more source

Adenosine and Adenosine Receptors [PDF]

open access: possibleAmerican Journal of Respiratory Cell and Molecular Biology, 1990
In the last decade, there has been renewed interest in extracellular signaling by adenosine and adenine nucleotides. The potent cardiovascular effects of these agents were originally described by Drury and Szent-Gy6rgyi in 1929 (1). This report was followed by a flurry of interest in the use of adenosine as an antihypertensive agent, which subsided ...
openaire   +2 more sources

Adenosine and adenosine receptors in colorectal cancer

International Immunopharmacology, 2020
CD39 (nucleoside triphosphate diphosphohydrolase) and Ecto-5-nucleotidase (CD73) have been recognized as important factors mediating various pathological and physiological responses in the tumor microenvironment. Elevated expression of CD73 and CD39 is correlated with the over-production of adenosine in the tumor region.
A.V. Sevbitov   +7 more
openaire   +2 more sources

Interstitial adenosine with dipyridamole: effect of adenosine receptor blockade and adenosine deaminase

American Journal of Physiology-Heart and Circulatory Physiology, 1992
Dipyridamole is proposed to increase coronary blood flow (CBF) by inhibition of adenosine uptake into cells, resulting in an increase in interstitial fluid (ISF) adenosine and an adenosine-mediated vasodilation. The purpose of this study was to determine the changes in CBF and ISF adenosine, inosine, and hypoxanthine during dipyridamole infusion in ...
D. G. L. Van Wylen   +2 more
openaire   +3 more sources

Is adenosine deaminase involved in adenosine transport?

Medical Hypotheses, 1990
The hypothesis that adenosine metabolizing enzymes may have a key role in the transport of adenosine is discussed. The enhancement of adenosine transport by inhibitors of adenosine deaminase (the enzyme which deaminates adenosine to inosine) and the ecto-localization of adenosine deaminase suggest a contribution of the enzyme in taking up nucleosides ...
Josep J. Centelles, Rafael Franco
openaire   +3 more sources

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