Results 41 to 50 of about 215,850 (301)

Adenosine deaminase for diagnosis of tuberculous pleural effusion: A systematic review and meta-analysis

PLoS ONE, 2019
Objective Pleural fluid adenosine deaminase (ADA) is a useful diagnostic test for tuberculous pleural effusion (TPE), but its exact threshold and accuracy in clinical decision-making is unclear. We aimed to assess diagnostic performance of ADA in TPE and
A. Aggarwal, R. Agarwal, I. Sehgal, S. Dhooria   +3 more
semanticscholar   +1 more source

Deficiency of adenosine deaminase 2 triggers adenosine-mediated NETosis and TNF production in patients with DADA2.

Blood, 2019
Reduction of adenosine deaminase 2 (ADA2) activity due to autosomal recessive loss-of-function mutations in the ADA2 gene (previously known as CECR1) results in a systemic vasculitis known as deficiency of ADA2 (DADA2).
C. Carmona-Rivera, S. S. Khaznadar, K. Shwin, J. Irizarry-Caro, L. O’Neil, Yudong Liu, K. Jacobson, A. Ombrello, D. Stone, W. Tsai, D. Kastner, I. Aksentijevich, M. Kaplan, P. Grayson   +13 more
semanticscholar   +1 more source

Adenosine deaminase, (ADA) level in leprosy

International Journal of Medicine and Health Development, 2012
Background: Adenosine deaminase (ADA) is involved in and the catabolism of toxic de-oxynucleotides (5) and modulation of insulin action. Although its activities in leprosy have been measured, its characteristics have not been reported.
I S I Ogbu, I N Nnatuanya, J C Onyeanusi
doaj   +1 more source

Treatment Strategies for Deficiency of Adenosine Deaminase 2.

New England Journal of Medicine, 2019
Adenosine Deaminase 2 Deficiency and TNF Inhibition The manifestations of a deficiency of adenosine deaminase 2, a genetic disease, include early-onset lacunar stroke.
A. Ombrello, Jing Qin, P. Hoffmann, Parag Kumar, D. Stone, Anne Jones, T. Romeo, B. Barham, G. Pinto-Patarroyo, C. Toro, A. Soldatos, Qing Zhou, N. Deuitch, I. Aksentijevich, Sherry L. Sheldon, S. Kelly, Ada Man, K. Barron, M. Hershfield, W. Flegel, D. Kastner   +20 more
semanticscholar   +1 more source

L-Arginine Intake Effect on Adenine Nucleotide Metabolism in Rat Parenchymal and Reproductive Tissues

The Scientific World Journal, 2012
L-arginine is conditionally essetcial amino acid, required for normal cell growth, protein synthesis, ammonia detoxification, tissue growth and general performance, proposed in the treatment of men sterility and prevention of male impotence.
G. Kocic, J. Nikolic, T. Jevtovic-Stoimenov, D. Sokolovic, H. Kocic, T. Cvetkovic, D. Pavlovic, A. Cencic, D. Stojanovic   +8 more
doaj   +1 more source

The Diagnostic Efficacy of Adenosine Deaminase in Tubercular Effusion

Oman Medical Journal, 2013
Objective: This study aims to evaluate the diagnostic efficacy of adenosine deaminase in tubercular effusions.Methods: This study was conducted at the Department of General Medicine and Cardiovascular and Thoracic Surgery, SKIMS, for a period of two ...
Mohd Arif Kelam, Farooq Ahmad Ganie, Bashir Ahmad Shah, Shabir Ahmad Ganie, Mohd Lateef Wani, Nasir-U-Din Wani, Masaratul Gani   +6 more
doaj   +1 more source

Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis

Brain : a journal of neurology, 2019
Using metabolic screening, Allen et al. identify an adenosine to inosine deamination defect in astrocytes from ALS patients. This defect is the result of reduced expression of adenosine deaminase, leading to increased susceptibility to adenosine-mediated
Scott P. Allen, Benjamin Hall, L. Castelli, Laura Francis, Ryan Woof, A. Siskos, Eirini Kouloura, E. Gray, A. Thompson, K. Talbot, A. Higginbottom, Monika A. Myszczynska, Chloe F. Allen, Matthew J. Stopford, Jordan Hemingway, C. Bauer, Christopher P. Webster, K. D. De Vos, M. Turner, H. Keun, Guillaume M. Hautbergue, L. Ferraiuolo, P. Shaw   +22 more
semanticscholar   +1 more source

Author Correction: Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells

Nature Communications, 2018
Systematic exploration of cancer cell vulnerabilities can inform the development of novel cancer therapeutics. Here, through analysis of genome-scale loss-of-function datasets, we identify adenosine deaminase acting on RNA (ADAR or ADAR1) as an essential
Hugh S. Gannon, T. Zou, M. Kiessling, G. Gao, D. Cai, P. Choi, Alexandru P Ivan, Ilana Buchumenski, Ashton C. Berger, Jonathan T. Goldstein, A. Cherniack, F. Vazquez, Aviad Tsherniak, E. Levanon, W. Hahn, M. Meyerson   +15 more
semanticscholar   +1 more source

Dosagem da atividade da adenosina deaminase no líquido pleural para o diagnóstico da tuberculose pleural Pleural fluid adenosine deaminase detection for the diagnosis of pleural tuberculosis

Jornal Brasileiro de Pneumologia, 2004
INTRODUÇÃO: O diagnóstico da tuberculose pleural permanece um desafio, pois a sensibilidade dos testes tradicionais é baixa. O exame histopatológico da pleura é o método mais preciso, com até 80% de sensibilidade.
Morrys Casagrande Kaisemann, Afrânio Lineu Kritski, Maria de Fátima C Pereira, Anete Trajman   +3 more
doaj   +1 more source

The Kinetic Study of Adenosine Deaminase Activity in Renal Failure Patients [PDF]

Kirkuk Journal of Science, 2011
Serum adenosine deaminase levels was measured in patients with acute renal failure and compare them with the results of healthy individuals. Serum adenosine deaminase levels were found to be significantly higher in patient with acute renal failure than ...
Lutfia M. Hassan, Parween A. Ismahail
doaj   +1 more source