Results 61 to 70 of about 29,706 (209)

Optimized TadA‐derived base editors efficiently manipulate mRNA splicing by A‐to‐G and C‐to‐K editing in potato

Journal of Integrative Plant Biology, EarlyView.
Two optimized TadA‐derived base editors efficiently generate diverse splicing variants by targeting specific splice sites in potato. ABSTRACT Pre‐messenger RNA (pre‐mRNA) splicing is a critical mechanism for post‐transcriptional regulation in plants. Through alternative splicing, plants produce diverse transcriptomes and proteomes that finely regulate ...
Kaiyuan Chen, Yan Zhang, Jiuzhou Deng, Lumin Zhang, Huiying Zhou, Yaxin Duan, Enle Xiao, Guangtao Zhu, Chunzhi Zhang   +8 more
wiley   +1 more source

Predictive Ability of Sonographic Characteristics Alone to Diagnose Tuberculous Pleural Effusions in a Resource‐Limited Setting: A Cross‐Sectional Pilot Study in Zambia

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Tuberculous pleural effusion (TPE), the second most common form of extra‐pulmonary tuberculosis (TB), remains difficult to diagnose due to low‐yield, invasive and often unavailable diagnostics in resource‐limited settings. This study aimed to evaluate the diagnostic accuracy of sonographic characteristics alone to predict TB ...
Lukonde Zimba, Salomé‐Joëlle Gass, Mpundu C. Makasa, Matthew S. Haldeman   +3 more
wiley   +1 more source

Challenging the prokaryotic MGE‐defense origin of eukaryotic RNA editing

mLife, EarlyView.
Yuange Duan, Qiuhua Xie, Jiajia Yang, Wanzhi Cai, Hu Li   +4 more
wiley   +1 more source

Acute pain transfusion reaction in a patient with thalassemia: In‐depth characterization of short‐ and long‐term phenotypes

Transfusion, EarlyView.
Abstract Background Acute pain transfusion reaction (APTR) is a rare, under‐recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. Study Design and Methods Here, we present an APTR event in an adult subject with transfusion‐dependent thalassemia
Georgia Tzafa, Sophia Delicou, Ioanna Barla, Konstantina Theocharaki, Aggeliki Kondi, Athanassios D. Velentzas, Nikolaos Simantiris, Elli‐Anna Stylianaki, George Mpekoulis, Efthymia Pavlou, Niki Vassilaki, Ioannis V. Kostopoulos, Aikaterini Xydaki, Efrosyni Nomikou, Ioanna‐Katerina Aggeli, Nikolaos Thomaidis, Evangelos Gikas, Martina Samiotaki, Jerome Zoidakis, Constantina Politis, Marianna H. Antonelou   +20 more
wiley   +1 more source

SIGNIFICANCE OF ADENOSINE DEAMINASE SERUM CONCENTRATIONS IN THE DIAGNOSIS OF EXTRA-PULMONARY TUBERCULOSIS [PDF]

Journal of IMAB, 2011
Extra pulmonary tuberculosis (EPTB) is a growing problem worldwide. Due to the nature of the disease, the diversity of clinical pictures as well as its minor epidemiological importance, the diagnosis is difficult and often late.In addition to standard TB
Stevanovic G,, Pelemis M,, Pavlovic M,, Lavadinovic L,, Dakic Z,, Milosevic I,, Milosevic B.   +6 more
doaj  

Chemotherapy Effects on the Activities of Some Purine Metabolic Enzymes in Sera of Ovarian Cancer Patients

مجلة بغداد للعلوم, 2010
Adenosine deaminase (ADA; Ec: 3.5.4.4), 5´- Nucleotidase (5´– NT; Ec: 3.1.3.5), and AMP – amino hydrolase (AMP – deaminase AMPDA; Ec: 3.5.4.6) activities were measured in sera of ovarian cancer patients before surgery, and after chemotherapy.
Baghdad Science Journal
doaj   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source

Pleuroperitoneal Fistula, an Unusual Case of Recurrent Unilateral Transudative Pleural Effusion

Respirology Case Reports, Volume 14, Issue 7, July 2026.
A 39‐year‐old woman afflicted by SLE with musculoskeletal involvement and ESRF on CAPD presented with recurrent left‐sided transudative pleural effusion. Guided by a glucose gradient of 2.6 mmol/L and further confirmatory tests via CT peritoneography, a diagnosis of a pleuroperitoneal leak was secured. ABSTRACT A 39‐year‐old woman afflicted by systemic
Collin Kah Jing Lo, Yi‐De Ng, Grace Sook Hoon Low, Leng Cheng Sia   +3 more
wiley   +1 more source

Adenosine deaminase (ADA) level in tubercular pleural effusion

Lung India, 2008
Study objective : To study the value of adenosine deaminase level in tuber-cular pleural effusion. Design: A hospital based observational study. Setting : Out and In patients service of department of Tuberculosis & Chest Diseases, MLN Medical ...
Verma S, Dubey A, Singh P, Tewerson S, Sharma Devashish   +4 more
doaj