Results 81 to 90 of about 29,706 (209)

Diagnostic value of serum Adenosine deaminase and its isoenzymes in the diagnosis of pulmonary tuberculosis

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2008
Background & Objective: Adenosine deaminase is an enzyme which catalyses adenosine to Inosine. The determination of adenosine deaminase in body fluids is important for the diagnosis of tuberculosis.
Hamid Reza Joshaghani   +3 more
doaj  

Progress and Challenges in Faba Bean Genetic Engineering

open access: yesLegume Science, Volume 8, Issue 2, June 2026.
ABSTRACT Legumes are essential for global food security, serving as a vital source of plant‐based protein and playing a significant role in sustainable agricultural practices. Among legumes, faba bean (Vicia faba L.) is noteworthy due to its high‐protein content, broad climate adaptation, and suitability for cultivation in temperate regions.
Simone A. Gierlich   +7 more
wiley   +1 more source

Gut Microbiota Alterations Associated With Colonization by Multidrug‐Resistant Organisms in ICU Patients: First Systematic Review and Meta‐Analysis

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
Microbiota profiling showed colonized critically ill patients had lower values of dominance/evenness (Simpson's index) and richness (Observed), reaching significantly lower values of information (mean difference in Shannon index = –1.18; 95% CI, –1.84 to –0.52; p < 0.001).
Andra‐Elena Goicea   +2 more
wiley   +1 more source

The Role of N6‐Methyladenosine Modification in Health and Disease

open access: yesMedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li   +6 more
wiley   +1 more source

Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang   +7 more
wiley   +1 more source

Theranostic Advancements in Brain Cancer: Promising Approaches for Emerging Therapy

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Strategies for improving intra‐arterial administration (A) and photodynamic therapy in brain cancer (B). Improving intra‐arterial (IA) administration and photodynamic therapy (PDT) for brain cancer involves enhancing tumor targeting and breaching the blood–brain barrier (BBB). Key strategies include super selective catheterization, using osmotic agents
Bipraban Khanra, Manoj Kumar Sarangi
wiley   +1 more source

Pulmonary Sarcoidosis Associated With Pleural Effusion: A Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 6, June 2026.
A rare case of pulmonary sarcoidosis presenting with bilateral pleural effusion is described in a young adult. Diagnosis was supported by characteristic radiological findings, lymphocyte‐predominant exudative pleural effusion and histological confirmation of non‐caseating granulomas via EBUS‐TBNA.
Shpëtim Thaçi   +3 more
wiley   +1 more source

Dynamic Switchable and Transient DNA Condensates Driven by Aptamer‐Ligand or Ion‐Nucleobase Bridged Complexes

open access: yesSmall, Volume 22, Issue 31, 2 June 2026.
Switchable or transient formation and dissociation of the phase‐separated DNA microdroplets generated by metal ions or aptamer‐ligand complexes crosslinking Y‐shaped DNA frameworks and dynamically separated by counter ligands eliminating the bridging metal ions or biocatalysts degrading the aptamer‐ligand complexes, are introduced.
Yichen Han   +6 more
wiley   +1 more source

Effects of Chemotherapeutic Agents (5‐Fluorouracil, Cisplatin and Methotrexate) on Cell Adhesion Molecules and Oxidative Damage Markers in Rat Kidney Tissue

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 6, June 2026.
Chemotherapy with 5‐fluorouracil, cisplatin or methotrexate induces significant renal oxidative stress, DNA damage and dysregulation of apoptosis‐ and cell adhesion‐related proteins in rats. Cisplatin causes the most severe oxidative injury, whereas methotrexate predominantly alters apoptotic and cell adhesion pathways.
Serdar Emre Ozyapici   +2 more
wiley   +1 more source

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