Results 81 to 90 of about 132,212 (243)

A comparative study of the interaction between the conversion factor from human tissues with the small forms of adenosine deaminase from various organisms

, 1981
Two molecular forms of adenosine deaminase have been isolated from bovine livers. These two forms were found to be interconvertible. Adenosine deaminase extracted from human tissues exhibited similar properties as well.
Puttaswamy, Shashi
core  

The genetics of feto-placental development: A study of acid phosphatase locus 1 and adenosine deaminase polymorphisms in a consecutive series of newborn infants

Reproductive Biology and Endocrinology, 2008
Background Acid phosphatase locus 1 and adenosine deaminase locus 1 polymorphisms show cooperative effects on glucose metabolism and immunological functions.
Bergamaschi Antonio, Magrini Andrea, Coppeta Luca, Pietropolli Adalgisa, Gloria-Bottini Fulvia, Bottini Egidio   +5 more
doaj   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Frog adenosine deaminases.

, 1983
Adenosine deaminase has been shown to consist of three molecular weight forms, A, B, and C. In higher mammals, the A and C forms are dominant while in lower mammals, the B and C forms are dominant.
Cook, Kenneth Steven
core  

Serum adenosine deaminase and cytidine deaminase activities in patients with systemic lupus erythematosus

, 2002
We evaluated serum total adenosine deaminase, its isoenzymes adenosine deaminase-1 and adenosine deaminase-2, and cytidine deaminase activities in 24 patients with active systemic lupus erythematosus, and in 26 healthy control subjects, and found the ...
TAYSİ, S, POLAT, MUHAMMET FEVZİ, SARİ, RA, BAKAN, Ebubekir   +3 more
core   +1 more source

Gene therapy for adenosine deaminase deficiency

, 2003
PURPOSE OF REVIEW: Gene therapy for severe combined immunodeficiency due to adenosine deaminase deficiency has moved from the early trials of safety and feasibility to recent studies demonstrating efficacy and clinical benefit.
BORDIGNON, CLAUDIO, RONCAROLO , MARIA GRAZIA, CATTANEO F, AIUTI A, FICARA F   +4 more
core   +2 more sources

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Thin-layer gel-filtration studies of adenosine deaminase in normal and pathological human sera

, 1980
Previous studies of serum adenosine deaminase have neglected consideration of the two molecular forms of this enzyme that exist in human tissues. The purpose of this study was to survey the distribution of these forms in normal and pathological human ...
Frazier, Ronald Burdette
core  

Sensor‐Detected Hypoglycaemia Is Associated With Inflammatory Protein and Immune Cell Alterations in People With Diabetes: Findings From the Hypo‐METRICS Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Experimental hypoglycaemia induces a persistent inflammatory response. We investigated whether real‐life sensor‐detected hypoglycaemia (SDH) is associated with immune parameters in people with Type 1 and Type 2 diabetes and explored potential differences between the groups.
Mandala Ajie, Namam Ali, Marijn S. Hendriksz, Patrick Divilly, Marloes J. Rietveld, Evertine J. Abbink, Pratik Choudhary, Julie Maria Bøggild Brøsen, Ulrik Pedersen‐Bjergaard, Rory J. McCrimmon, Mark Evans, Julia K. Mader, Bastiaan E. de Galan, Rinke Stienstra, Cees J. Tack, on behalf of the Hypo‐RESOLVE Consortium   +15 more
wiley   +1 more source

Adenosine deaminase and adenosine attenuate ventricular arrhythmias caused by norepinephrine

, 1991
Twenty-five beagles weighing 9.1 +/- 0.4 kg were used to investigate the arrhythmogenic effects of divided doses of intracoronary norepinephrine (50-200 ng.kg-1.min-1) in the absence and the presence of adenosine deaminase (5 U.kg-1.min-1).
G. S. Friedrichs, G. F. Merrill
core   +1 more source