Results 81 to 90 of about 29,706 (209)
Background & Objective: Adenosine deaminase is an enzyme which catalyses adenosine to Inosine. The determination of adenosine deaminase in body fluids is important for the diagnosis of tuberculosis.
Hamid Reza Joshaghani +3 more
doaj
Progress and Challenges in Faba Bean Genetic Engineering
ABSTRACT Legumes are essential for global food security, serving as a vital source of plant‐based protein and playing a significant role in sustainable agricultural practices. Among legumes, faba bean (Vicia faba L.) is noteworthy due to its high‐protein content, broad climate adaptation, and suitability for cultivation in temperate regions.
Simone A. Gierlich +7 more
wiley +1 more source
Microbiota profiling showed colonized critically ill patients had lower values of dominance/evenness (Simpson's index) and richness (Observed), reaching significantly lower values of information (mean difference in Shannon index = –1.18; 95% CI, –1.84 to –0.52; p < 0.001).
Andra‐Elena Goicea +2 more
wiley +1 more source
The Role of N6‐Methyladenosine Modification in Health and Disease
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li +6 more
wiley +1 more source
Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang +7 more
wiley +1 more source
Theranostic Advancements in Brain Cancer: Promising Approaches for Emerging Therapy
Strategies for improving intra‐arterial administration (A) and photodynamic therapy in brain cancer (B). Improving intra‐arterial (IA) administration and photodynamic therapy (PDT) for brain cancer involves enhancing tumor targeting and breaching the blood–brain barrier (BBB). Key strategies include super selective catheterization, using osmotic agents
Bipraban Khanra, Manoj Kumar Sarangi
wiley +1 more source
Pulmonary Sarcoidosis Associated With Pleural Effusion: A Case Report
A rare case of pulmonary sarcoidosis presenting with bilateral pleural effusion is described in a young adult. Diagnosis was supported by characteristic radiological findings, lymphocyte‐predominant exudative pleural effusion and histological confirmation of non‐caseating granulomas via EBUS‐TBNA.
Shpëtim Thaçi +3 more
wiley +1 more source
Switchable or transient formation and dissociation of the phase‐separated DNA microdroplets generated by metal ions or aptamer‐ligand complexes crosslinking Y‐shaped DNA frameworks and dynamically separated by counter ligands eliminating the bridging metal ions or biocatalysts degrading the aptamer‐ligand complexes, are introduced.
Yichen Han +6 more
wiley +1 more source
Chemotherapy with 5‐fluorouracil, cisplatin or methotrexate induces significant renal oxidative stress, DNA damage and dysregulation of apoptosis‐ and cell adhesion‐related proteins in rats. Cisplatin causes the most severe oxidative injury, whereas methotrexate predominantly alters apoptotic and cell adhesion pathways.
Serdar Emre Ozyapici +2 more
wiley +1 more source

