Results 101 to 110 of about 54,805 (241)

Adenosine deaminase (ADA) level in tubercular pleural effusion

Lung India, 2008
Study objective : To study the value of adenosine deaminase level in tuber-cular pleural effusion. Design: A hospital based observational study. Setting : Out and In patients service of department of Tuberculosis & Chest Diseases, MLN Medical ...
Verma S, Dubey A, Singh P, Tewerson S, Sharma Devashish   +4 more
doaj  

Atypical phenotype of an old disease or typical phenotype of a new disease: deficiency of adenosine deaminase 2

The Turkish Journal of Pediatrics, 2019
Deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessive autoinflammatory disorder caused by mutations in CECR1 (cat eye syndrome chromosome region, canditate 1) gene, which encodes the enzyme adenosine deaminase 2 necessary for endothelial
Mustafa Çakan, Nuray Aktay-Ayaz, Şerife Gül Karadağ, Eda Tahir-Turanlı, Kelsey Stafstrom, Wayne Bainter, Raif S Geha, Janet Chou   +7 more
doaj   +1 more source

Mini‐Catalytically Inactive Cas13X‐Derived RNA Base Editing of β‐Catenin Attenuates Pulmonary Damage in a Murine Acute Lung Injury Model

MedComm, Volume 7, Issue 4, April 2026.
AAV6.2FF‐delivered CARTEL (mini‐dCas13X‐mediated A‐to‐I editor) introduces c.121A>G editing in β‐catenin RNA of alveolar type II cells, leading to sustained Wnt/β‐catenin activation, robust AT2 proliferation, significant attenuation of LPS‐induced acute lung injury, and no excess off‐target edits or fibrotic toxicity for 4 weeks.
Wenyi Liu, Wanda Bi, Saiying Hou, Juan Du, Ling Zeng, Anqiang Zhang, Huacai Zhang, Dalin Wen, Qingli Cai, Chu Gao, Ping Lin, Min Wu, Li Li, Jianxin Jiang   +13 more
wiley   +1 more source

Laboratorial validation of an automated assay for the determination of adenosine deaminase activity in pleural fluid and cerebrospinal fluid [PDF]

, 2008
OBJECTIVE: The incidence of tuberculosis worldwide has emphasized the need for better assays designed to diagnose the disease, principally the extrapulmonary form.
Batista, Fernando, Feres, Márcia Cristina, Gabriel Júnior, Alexandre, Maldijian, Suely, Martino, Maria Cristina de, Tufik, Sergio   +5 more
core   +3 more sources

Immunocompromised Status Definition in Observational Studies Using Electronic Health Records: A Scoping Review and a Proposal for a Phenotype Identification Algorithm

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 4, April 2026.
ABSTRACT Immunocompromised individuals experience an impaired immune function due to conditions that might be either congenital or acquired over the course of their lives. Epidemiological studies often rely on clinical definitions which, in some cases, benefit from being translated into machine‐readable algorithms for application to electronic health ...
Judit Riera‐Arnau, Nicoletta Luxi, Fabio Riefolo, Martín Solorzano, Irene Pazos, Elena Ballarín, Lise Skovgaard Svingel, Lorenzo Chiusaroli, Elisa Martín‐Merino, Elisa Barbieri, María Lopez‐Lasanta, Sima Mohammadi, Denis Rotta, Alexandra Pacurariu, Catherine Cohet, Miriam Sturkenboom, Carlos E. Durán, on behalf of the SAFETY‐VAC study consortium, Carlos E. Durán, Miriam Sturkenboom, Judit Riera‐Arnau, Nicoletta Luxi, Olaf Klungel, Patrick Souverein, Sima Mohammadi, Fabio Riefolo, Irene Pazos, Rosa Gini, Davide Messina, Giuseppe Roberto, Carlo Giaquinto, Elisa Barbieri, Luca Stona, Felipe Villalobos, Martín Solorzano, Carlo Alberto Bissacco, Antonio Gimeno, Beatriz Poblador, Mercedes Aza, Aida Moreno, Alejandro Santos, Vera Ehrenstein, Lise Skovgaard Svingel, Benjamin Randeris Johannesen, Cécile Droz‐Perroteau, Laure Carcaillon‐Bentata, Anna‐Mija Tolppanen, Sirpa Hartikainen, Thuan Vo, Anne Paakinaho, Blair Rajamaki, Hedvig Nordeng, Saeed Hayati, Mahmoud Zidan, Juan José Carreras Martínez, Arantxa Urchueguía Fornes, Elisa Correcher Martínez, Javier Díez‐Domingo, Mar Martin, Patricia Garcia‐Poza, Airam de Burgos, Belén Castillo‐Cano, Elisa Martín‐Merino   +62 more
wiley   +1 more source

Adenosine Deaminase Activity in COPD Patients and Healthy Subjects

Iranian Journal of Allergy, Asthma and Immunology, 2010
Chronic obstructive pulmonary disease (COPD) has been defined by the Global Initiative for Chronic Obstructive Lung Disease (GOLD), as a disease state characterized by airflow limitation which is not fully reversible.
Mohammad Taghi Goodarzi, Mohammad Abdi, Heidar Tavilani, Ebrahim Nadi, Mojtaba Rashidi   +4 more
doaj  

Milky Effusion in Giant Empyema Caused by Streptococcus viridans

Respirology Case Reports, Volume 14, Issue 4, April 2026.
This case underscores the importance of biochemical and microbiological evaluation in distinguishing empyema from chylothorax and highlights S. viridans as a rare cause of giant empyema, particularly in patients with diabetes or immune compromise. ABSTRACT Milky pleural effusion usually suggests chylothorax.
Guo Li, Min Pang, Ming‐ming Yang, Xian‐qiong Pang   +3 more
wiley   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

When R‐Loops Go Awry: Genome Instability and Neurological Diseases

European Journal of Neuroscience, Volume 63, Issue 8, April 2026.
DNA normally exists as a double helix formed by two complementary strands. During gene transcription, however, one strand of DNA can bind to RNA, causing the other DNA strand to be displaced. This creates a structure called an R‐loop. R‐loops play important roles in normal cellular processes such as gene expression, DNA replication, and transcription ...
Nur Rasyiqin Rasli, Yu Katsuyama
wiley   +1 more source

Update on diagnosis, nonpharmacological treatment and prevention of Equine Gastric Ulcer Syndrome (EGUS)

Equine Veterinary Education, Volume 38, Issue 4, Page 206-219, April 2026.
Summary The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999. As there are important differences, the terms Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD) were introduced in 2015. Risk factors like dietary management, training regimens and drug side effects, as described for NSAIDs, predispose ...
R. Lensing, A. K. Barton
wiley   +1 more source