Results 1 to 10 of about 55,507 (167)
Expression of poly(Adenosine Diphosphate-Ribose) polymerase protein in breast cancer [PDF]
Journal of Mid-Life Health, 2022 Background: The use of poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitors for breast cancer (BC) therapy is the subject of debate, and there is an urgent need to understand much the expression and prognostic role of the PARP1 protein.
Akanksha +6 more
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The Impact of Cold Storage on Adenosine Diphosphate-Mediated Platelet Responsiveness [PDF]
TH Open, 2020 Introduction Cold storage of platelets is considered to contribute to lower risk of bacterial growth and to more efficient hemostatic capacity. For the optimization of storage strategies, it is required to further elucidate the influence of refrigeration
Juergen Koessler +6 more
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A pan‐tumor review of the role of poly(adenosine diphosphate ribose) polymerase inhibitors [PDF]
Ca-A Cancer Journal for CliniciansJennifer Litton +2 more
exaly +2 more sources
Purinergic Signaling in the Regulation of Gout Flare and Resolution
Frontiers in Immunology, 2021 Gout flares require monosodium urate (MSU) to activate the NLRP3 inflammasome and secrete sufficient IL-1β. However, MSU alone is not sufficient to cause a flare. This is supported by the evidence that most patients with hyperuricemia do not develop gout
Xiaoling Li, Jie Gao, Jinhui Tao
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Platelet aggregation and von Willebrand factor in patients with artherial hypertension combined with osteoarthritis [PDF]
Ķazaķstannyṇ Klinikalyķ Medicinasy, 2017 Objective: To investigate the platelet aggregation and level of von Willebrand factor in patients with hypertension and knee osteoarthritis.
Viktoriya Rodionova, Olena Khmel
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Molbank, 2022 Cyclic adenosine diphosphate ribose (cADPR) is a cyclic nucleotide involved in the Ca2+ homeostasis. In its structure, the northern ribose, bonded to adenosine through an N1 glycosidic bond, is connected to the southern ribose through a pyrophosphate ...
Maria Marzano +5 more
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Adenosine diphosphate ribosylated histones [PDF]
Biochemical Journal, 1977 When rat liver nuclei were incubated with [adenine-3H]NAD, besides histone 1, histone 2A and especially histone 2B accepted 3H radioactivity. 3H radioactivity was also found on the non-histone proteins and on the small amounts of histones 1 and 3 released into the supernatant during incubation.
M G, Ord, L A, Stocken
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Structure/function analysis of PARP-1 in oxidative and nitrosative stress-induced monomeric ADPR formation. [PDF]
PLoS ONE, 2009 Poly adenosine diphosphate-ribose polymerase-1 (PARP-1) is a multifunctional enzyme that is involved in two major cellular responses to oxidative and nitrosative (O/N) stress: detection and response to DNA damage via formation of protein-bound poly ...
Ben Buelow +3 more
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An arsenical analogue of adenosine diphosphate [PDF]
Biochemical Journal, 1978 An analogue of ADP was made in which the terminal phosphono-oxy group, -O-PO(OH)2, has been replaced by the arsonomethyl group, -CH2-AsO(OH)2. This compound cannot form a stable analogue of ATP because anhydrides of arsonic acids are rapidly hydrolysed, so that any enzyme that phosphorylates ADP and accepts this analogue as a substrate should release ...
D, Webster, M J, Sparkes, H B, Dixon
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Haematologica, 2012 Background The interaction of adenosine diphosphate with its P2Y1 and P2Y12 receptors on platelets is important for platelet function. However, nothing is known about adenosine diphosphate and its function in human megakaryocytes.Design and Methods We ...
Alessandra Balduini +8 more
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