Results 1 to 10 of about 103,074 (260)
Expression of poly(Adenosine Diphosphate-Ribose) polymerase protein in breast cancer [PDF]
Background: The use of poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitors for breast cancer (BC) therapy is the subject of debate, and there is an urgent need to understand much the expression and prognostic role of the PARP1 protein.
Akanksha +6 more
doaj +2 more sources
Adenosine diphosphate and the measurement of platelet adhesiveness [PDF]
Platelet adhesiveness to glass beads was measured in citrated blood at intervals up to two hours after the addition of adenosine diphosphate (A.D.P.). Adhesiveness increased for 15 minutes, fell towards the original level, and then steadily increased.
Arnold Bloom, Alison Davies
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The Impact of Cold Storage on Adenosine Diphosphate-Mediated Platelet Responsiveness [PDF]
Introduction Cold storage of platelets is considered to contribute to lower risk of bacterial growth and to more efficient hemostatic capacity. For the optimization of storage strategies, it is required to further elucidate the influence of refrigeration
Juergen Koessler +6 more
doaj +2 more sources
Adenosine Diphosphate Glucose and Glucoside Biosynthesis [PDF]
URIDINE diphosphate glucose (UDPG) has been found to act as glucose donor in a number of enzymatic reactions, such as glucoside formation in plants1 and in locust2, sucrose and starch synthesis in plants3,4 and glycogen formation in mammals5.
Juan Carlos Trivelloni +2 more
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Purinergic Signaling in the Regulation of Gout Flare and Resolution
Gout flares require monosodium urate (MSU) to activate the NLRP3 inflammasome and secrete sufficient IL-1β. However, MSU alone is not sufficient to cause a flare. This is supported by the evidence that most patients with hyperuricemia do not develop gout
Xiaoling Li, Jie Gao, Jinhui Tao
doaj +1 more source
Cyclic adenosine diphosphate ribose (cADPR) is a cyclic nucleotide involved in the Ca2+ homeostasis. In its structure, the northern ribose, bonded to adenosine through an N1 glycosidic bond, is connected to the southern ribose through a pyrophosphate ...
Maria Marzano +5 more
doaj +1 more source
Platelet aggregation and von Willebrand factor in patients with artherial hypertension combined with osteoarthritis [PDF]
Objective: To investigate the platelet aggregation and level of von Willebrand factor in patients with hypertension and knee osteoarthritis.
Viktoriya Rodionova, Olena Khmel
doaj +1 more source
Adenosine diphosphate ribosylated histones [PDF]
When rat liver nuclei were incubated with [adenine-3H]NAD, besides histone 1, histone 2A and especially histone 2B accepted 3H radioactivity. 3H radioactivity was also found on the non-histone proteins and on the small amounts of histones 1 and 3 released into the supernatant during incubation.
Lloyd A. Stocken, M G Ord
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Structure/function analysis of PARP-1 in oxidative and nitrosative stress-induced monomeric ADPR formation. [PDF]
Poly adenosine diphosphate-ribose polymerase-1 (PARP-1) is a multifunctional enzyme that is involved in two major cellular responses to oxidative and nitrosative (O/N) stress: detection and response to DNA damage via formation of protein-bound poly ...
Ben Buelow +3 more
doaj +1 more source
An arsenical analogue of adenosine diphosphate [PDF]
An analogue of ADP was made in which the terminal phosphono-oxy group, -O-PO(OH)2, has been replaced by the arsonomethyl group, -CH2-AsO(OH)2. This compound cannot form a stable analogue of ATP because anhydrides of arsonic acids are rapidly hydrolysed, so that any enzyme that phosphorylates ADP and accepts this analogue as a substrate should release ...
Michael J. Sparkes +2 more
openaire +3 more sources

