Expression of poly(Adenosine Diphosphate-Ribose) polymerase protein in breast cancer [PDF]
Background: The use of poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitors for breast cancer (BC) therapy is the subject of debate, and there is an urgent need to understand much the expression and prognostic role of the PARP1 protein.
Akanksha +6 more
doaj +2 more sources
The Impact of Cold Storage on Adenosine Diphosphate-Mediated Platelet Responsiveness [PDF]
Introduction Cold storage of platelets is considered to contribute to lower risk of bacterial growth and to more efficient hemostatic capacity. For the optimization of storage strategies, it is required to further elucidate the influence of refrigeration
Juergen Koessler +6 more
doaj +2 more sources
Accumulation of poly (adenosine diphosphate-ribose) by sustained supply of calcium inducing mitochondrial stress in pancreatic cancer cells. [PDF]
Jeong KY, Sim JJ, Park M, Kim HM.
europepmc +2 more sources
Tze-Wen Chung,1,3 Pei-Yi Lin,2 Shoei-Shen Wang,2 Yen-Fung Chen31Department of Biomedical Engineering, National Yang-Ming University, 2Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan, Republic of China; 3Department of Chemical ...
Chung TW, Lin PY, Wang SS, Chen YF
doaj +3 more sources
Synthesis and characterization of 2'-adenosine diphosphate and 3'-adenosine diphosphate
2'-adenosine diphosphate and 3'-adenosine diphosphate were made from the corresponding unprotected nucleoside monophosphates using phosphoramidic acid. This synthesis of the pyrophosphate link was stimulated by pyridine. Both compounds were more labile than 5'-ADP, and they were shown to degrade by two separate routes.
Ronald E. J. Mitchel
openalex +2 more sources
Role of Poly Adenosine Diphosphate Ribose Polymerase Inhibitors in Advanced Stage Ovarian Cancer. [PDF]
Arora E +5 more
europepmc +3 more sources
Purinergic Signaling in the Regulation of Gout Flare and Resolution
Gout flares require monosodium urate (MSU) to activate the NLRP3 inflammasome and secrete sufficient IL-1β. However, MSU alone is not sufficient to cause a flare. This is supported by the evidence that most patients with hyperuricemia do not develop gout
Xiaoling Li, Jie Gao, Jinhui Tao
doaj +1 more source
Cyclic adenosine diphosphate ribose (cADPR) is a cyclic nucleotide involved in the Ca2+ homeostasis. In its structure, the northern ribose, bonded to adenosine through an N1 glycosidic bond, is connected to the southern ribose through a pyrophosphate ...
Maria Marzano +5 more
doaj +1 more source
Platelet aggregation and von Willebrand factor in patients with artherial hypertension combined with osteoarthritis [PDF]
Objective: To investigate the platelet aggregation and level of von Willebrand factor in patients with hypertension and knee osteoarthritis.
Viktoriya Rodionova, Olena Khmel
doaj +1 more source
Latin American Challenges and Recommendations for Poly Adenosine Diphosphate Ribose Polymerase Inhibitor Treatment in Metastatic Castration Resistant Prostate Cancer: An Expert Overview. [PDF]
Borges Dos Reis R +9 more
europepmc +2 more sources

