Results 1 to 10 of about 288,808 (285)

Poly(adenosine diphosphate ribose) polymerase inhibitors induce autophagy-mediated drug resistance in ovarian cancer cells, xenografts, and patient-derived xenograft models. [PDF]

open access: yesCancer, 2020
Poly(adenosine diphosphate ribose) polymerase (PARP) inhibitors exhibit promising activity against ovarian cancers, but their efficacy can be limited by acquired drug resistance.
Santiago-O'Farrill JM   +17 more
europepmc   +2 more sources

Expression of poly(Adenosine Diphosphate-Ribose) polymerase protein in breast cancer [PDF]

open access: yesJournal of Mid-Life Health, 2022
Background: The use of poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitors for breast cancer (BC) therapy is the subject of debate, and there is an urgent need to understand much the expression and prognostic role of the PARP1 protein.
Akanksha   +6 more
doaj   +2 more sources

Constitutively released adenosine diphosphate regulates proplatelet formation by human megakaryocytes

open access: yesHaematologica, 2012
Background The interaction of adenosine diphosphate with its P2Y1 and P2Y12 receptors on platelets is important for platelet function. However, nothing is known about adenosine diphosphate and its function in human megakaryocytes.Design and Methods We ...
Alessandra Balduini   +8 more
doaj   +2 more sources

Association of Bleeding Scores and Platelet Transfusions With Platelet Counts and Closure Times in Response to Adenosine Diphosphate (CT-ADPs) Among Preterm Neonates With Thrombocytopenia.

open access: yesJAMA Netw Open, 2020
This cohort study analyzes the association of closure time in response to adenosine diphosphate (CT-ADP) with bleeding score and the associations of platelet transfusions with change in platelet count, CT-ADP, and bleeding scores in preterm neonates with
Deschmann E   +5 more
europepmc   +2 more sources

Adenosine diphosphate and the measurement of platelet adhesiveness [PDF]

open access: bronzeJournal of Clinical Pathology, 1967
Platelet adhesiveness to glass beads was measured in citrated blood at intervals up to two hours after the addition of adenosine diphosphate (A.D.P.). Adhesiveness increased for 15 minutes, fell towards the original level, and then steadily increased.
Arnold Bloom, Alison Davies
openalex   +5 more sources

The Impact of Cold Storage on Adenosine Diphosphate-Mediated Platelet Responsiveness [PDF]

open access: yesTH Open, 2020
Introduction Cold storage of platelets is considered to contribute to lower risk of bacterial growth and to more efficient hemostatic capacity. For the optimization of storage strategies, it is required to further elucidate the influence of refrigeration
Juergen Koessler   +6 more
doaj   +2 more sources

Adenosine Diphosphate Glucose and Glucoside Biosynthesis [PDF]

open access: bronzeNature, 1962
URIDINE diphosphate glucose (UDPG) has been found to act as glucose donor in a number of enzymatic reactions, such as glucoside formation in plants1 and in locust2, sucrose and starch synthesis in plants3,4 and glycogen formation in mammals5.
Juan Carlos Trivelloni   +2 more
openalex   +4 more sources

Azulene-based fluorescent chemosensor for adenosine diphosphate.

open access: yesChemical Communications, 2021
AzuFluor® 435-DPA-Zn, an azulene fluorophore bearing two zinc(II)-dipicolylamine receptor motifs, exhibits fluorescence enhancement in the presence of adenosine diphosphate.
Carlos M López-Alled   +9 more
semanticscholar   +1 more source

Purinergic Signaling in the Regulation of Gout Flare and Resolution

open access: yesFrontiers in Immunology, 2021
Gout flares require monosodium urate (MSU) to activate the NLRP3 inflammasome and secrete sufficient IL-1β. However, MSU alone is not sufficient to cause a flare. This is supported by the evidence that most patients with hyperuricemia do not develop gout
Xiaoling Li, Jie Gao, Jinhui Tao
doaj   +1 more source

O6-[(2″,3″-O-Isopropylidene-5″-O-tbutyldimethylsilyl)pentyl]-5′-O-tbutyldiphenylsilyl-2′,3′-O-isopropylideneinosine

open access: yesMolbank, 2022
Cyclic adenosine diphosphate ribose (cADPR) is a cyclic nucleotide involved in the Ca2+ homeostasis. In its structure, the northern ribose, bonded to adenosine through an N1 glycosidic bond, is connected to the southern ribose through a pyrophosphate ...
Maria Marzano   +5 more
doaj   +1 more source

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