Results 1 to 10 of about 92,139 (169)

NMR of $^{31}$P Nuclear Spin Singlet States in Organic Diphosphates [PDF]

, 2021
$^{31}$P NMR and MRI are commonly used to study organophosphates that are central to cellular energy metabolism. In some molecules of interest, such as adenosine diphosphate (ADP) and nicotinamide adenine dinucleotide (NAD), pairs of coupled $^{31}$P nuclei in the diphosphate moiety should enable the creation of nuclear spin singlet states, which may ...
arxiv   +1 more source

Transient behaviour towards the stable limit cycle in the Selkov model of Glycolysis: A physiological disorder [PDF]

Physica A 567 (2021) 125684, 2020
A simplified model for the complex glycolytic process was historically proposed by Selkov. It showed the existence of stable limit cycle as an example of Poincare-Bendixson theorem. This limit cycle is nothing but the time eliminated Lissajous plot of the concentrations of Adenosine-diphosphate (ADP) and Fructose-6-phosphate (F6P) of a normal/healthy ...
arxiv   +1 more source

Efficient adiabatic demagnetization refrigeration to below 50 mK with UHV compatible Ytterbium diphosphates $A$YbP$_2$O$_7$ ($A=$Na, K) [PDF]

Phys. Rev. Applied 20, 014013 (2023), 2023
Attaining milli-Kelvin temperatures is often a prerequisite for the study of novel quantum phenomena and the operation of quantum devices. Adiabatic demagnetization refrigeration (ADR) is an effective, easy and sustainable alternative to evaporation or dilution cooling with the rare and super-expensive $^3$He. Paramagnetic salts, traditionally used for
arxiv   +1 more source

Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC [PDF]

, 2012
Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways.
Alberto Contreras-Sanz, BD Gill, C Crawford, Claire M. Peppiatt-Wildman, DR Ferguson, DR Schneider, EM Schwiebert, EW Inscho, EW Inscho, FQ Yang, G Burnstock, G Burnstock, G Burnstock, G Manfredi, G Xu, HA Neufeld, HA Praetorius, HA Praetorius, Hardyal S. Gill, HM Liebich, I Kugelgen von, I Kugelgen von, J Czarnecka, James Malone-Lee, JC Mathies, Jennifer C. Jacoby, JM Buescher, JO Svensson, JR Gever, K Sugaya, Kevin M. G. Taylor, KH Schram, KR Kim, LA Birder, LC Rump, LD Todorov, M Cichna, M Katayama, MA Bailey, N Ozer, N Yamaoka, NS Zur, P Bodin, P Vinas, PD Wilson, R Corriden, RC Calvert, Rebecca E. Birch, RL Cordell, S Tatur, S Wiener, SA Levesque, Scott S. P. Wildman, Toby S. Scott-Ward, V Jankowski, V Kumar, W Yu, Y Cheng, Y Sun, Y Sun, Y Zheng   +60 more
core   +2 more sources

Neurogenetics of the Human Adenosine Receptor Genes: Genetic Structures and Involvement in Brain Diseases [PDF]

Journal of Caffeine and Adenosine Research, New Rochelle, N.Y. : Mary Ann Liebert, Inc., [2018]-, 2019, 9 (3), pp.73-88, 2020
Adenosine receptors are G-protein-coupled receptors involved in a wide range of physiological and pathological phenomena in most mammalian systems. All four receptors are widely expressed in the central nervous system, where they modulate neurotransmitter release and neuronal plasticity. A large number of gene association studies have shown that common
arxiv   +1 more source

Altered chemomechanical coupling causes impaired motility of the kinesin-4 motors KIF27 and KIF7. [PDF]

, 2018
Kinesin-4 motors play important roles in cell division, microtubule organization, and signaling. Understanding how motors perform their functions requires an understanding of their mechanochemical and motility properties.
Blasius, T Lynne, Cochran, Jared C, Grant, Barry J, Jariwala, Shashank, Verhey, Kristen J, Walker, Benjamin, Yue, Yang, Zhang, Stephanie   +7 more
core   +2 more sources

Crystallization of Adenylylsulfate Reductase from Desulfovibrio gigas: A Strategy Based on Controlled Protein Oligomerization [PDF]

, 2011
Adenylylsulfate reductase (adenosine 5′-phosphosulfate reductase, APS reductase or APSR, E.C.1.8.99.2) catalyzes the conversion of APS to sulfite in dissimilatory sulfate reduction. APSR was isolated and purified directly from massive anaerobically grown
Chan, Sunney I., Chen, Chun-Jung, Chiang, Yuan-Lan, Chuankhayan, Phimonphan, Fang, Jou-Yin, Hsieh, Yin-Cheng, Huang, Yen-Chieh, Liu, Ming-Yih, Wang, Vincent C.-C., Yang, Ming-Chi   +9 more
core   +1 more source

Utilization of a deoxynucleoside diphosphate substrate by HIV reverse transcriptase [PDF]

, 2008
Background: Deoxynucleoside triphosphates (dNTPs) are the normal substrates for DNA sysnthesis is catalyzed by polymerases such as HIV-1 reverse transcriptase (RT).
A Bevington, A Mas, AJ Smith, B Selmi, BA Barshop, BA Mulder, BR Bochner, C Cruchaga, C Isnard Bagnis, CK Tan, D Arion, EF Pettersen, G Pontarin, G Pontarin, G Yang, G Yang, GJ Kemp, H Huang, H Ling, H Pelletier, H Pelletier, HK Schachman, IA Nazarenko, K Bebenek, KL White, Kornberg, Linqi Zhang, M Rigourd, MC Franklin, Michael A. Parniak, MJ Bessman, MK Kukhanova, N Sluis-Cremer, PJ Rothwell, PL Boyer, PM Burgers, PM Burgers, PR Meyer, PR Meyer, PR Meyer, PR Meyer, PR Meyer, RS Fletcher, S Dharmasena, Scott J. Garforth, SJ Garforth, SV Doronin, SV Doronin, TA Kunkel, TA Rozovskaya, TA Steitz, UM Parikh, Vinayaka R. Prasad, Z Gu   +53 more
core   +7 more sources

Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells [PDF]

, 1990
Undifferentiated and differentiated HL-60 leukemic cells possess nucleotide receptors which functionally couple to phospholipase C via pertussis toxin-sensitive guanine nucleotide-binding proteins (G-proteins).
Seifert, Roland, Wenzel-Seifert, Katharina   +1 more
core   +1 more source

rLOAD: does sex mediate the effect of acute antiplatelet loading on stroke outcome. [PDF]

, 2014
BackgroundBiologic sex can influence response to pharmacologic therapy. The purpose of this proof-of-concept study was to evaluate the medicating effects of estrogen in the efficacy of acute antiplatelet loading therapy on stroke outcome in the rabbit ...
Compton, M Peggy, Eastwood, Jo-Ann, Gylys, Karen, Meyer, Dawn M, Zivin, Justin A   +4 more
core   +3 more sources