Results 141 to 150 of about 1,280 (195)

Stoichiometric mismatches between Australian showy mistletoes and their hosts: You are what you assimilate

open access: yesEcosphere, Volume 17, Issue 7, July 2026.
Abstract Ecological stoichiometry emphasizes that mismatches between the elemental composition of organisms and their resources can shape ecological interactions, evolutionary trajectories, and nutrient cycling. For hemiparasitic plants such as mistletoes, which draw water and nutrients from hosts while maintaining their own photosynthesis, such ...
Luis Y. Santiago‐Rosario   +2 more
wiley   +1 more source

Advances in the Neurotoxic Mechanisms of Acrylamide and Multitarget Intervention Strategies of Natural Products

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
This review summarizes recent advances in acrylamide neurotoxicity mechanisms and highlights the multitarget neuroprotective effects of diverse natural products while also addressing current challenges and future translational research directions.
Wen Du   +7 more
wiley   +1 more source

Exploring the Distinct Regulatory Actions and Molecular Pathways of Coptisine Through Network Pharmacology: Insights Into Its Influence on Platelet Activation and Thrombus Development

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
The methodological framework of this study integrates computational network pharmacology analysis with subsequent experimental validation. ABSTRACT To investigate the potential targets and underlying mechanisms of coptisine in regulating platelet activation and thrombosis by integrating an approach combining network pharmacology and experimental ...
Yanli Liu   +7 more
wiley   +1 more source

TRPM2 Deficiency Attenuates Allergic Rhinitis‐Like Inflammation With Altered Ca2+‐NFAT Signaling, Treg Responses, and sIgE Production

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 7, July 2026.
ABSTRACT Background Allergic rhinitis (AR) is a prevalent chronic inflammatory condition characterized by nasal itching, sneezing, and congestion, significantly impairing patients' quality of life. Despite the availability of various therapeutic options, treatment efficacy remains suboptimal for certain patients, and long‐term use may be accompanied by
Zhenke Huang   +5 more
wiley   +1 more source

Metabolome analysis identified exogenous cholesterol within lipid rafts that activate the Akt/mTOR signaling pathway in epithelial ovarian cancer

open access: yesInternational Journal of Cancer, Volume 159, Issue 1, Page 257-268, 1 July 2026.
What's New? Epithelial ovarian cancer (EOC) is a severe malignancy with few effective treatment options. While the mechanisms remain unclear, changes in lipid metabolism may fuel tumor growth and EOC progression, offering a possible path for new treatments.
Hitomi Sakaguchi‐Mukaida   +10 more
wiley   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

open access: yesInterdisciplinary Medicine, Volume 4, Issue 4, July 2026.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione   +2 more
wiley   +1 more source

Tricarboxylic Acid (TCA) Cycle Enzyme Alpha‐Ketoglutarate Dehydrogenase (KGDH) as a Nexus for the Regulation of Macrophage Polarization

open access: yesJournal of Cellular Biochemistry, Volume 127, Issue 7, July 2026.
ABSTRACT Macrophage metabolism has been increasingly studied in recent years for its potential as a therapeutic target across multiple pathologies. In this article, we propose that the tricarboxylic acid (TCA) cycle enzyme alpha‐ketoglutarate (KG) dehydrogenase (KGDH) serves as a nexus for regulating macrophage polarization toward pro‐inflammatory (M1)
Meijing Li, Ryan J. Mailloux
wiley   +1 more source

Contrasting CO2‐response strategies in Pardina lentils: Yield maximization in a commercial cultivar and seed composition adjustment in a landrace

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 9, Page 5422-5436, July 2026.
Abstract BACKGROUND Assessing crop's responses to elevated carbon dioxide (eCO2) is crucial for global food security. This study examines the impact of eCO2 (700 μmol mol−1) on the cultivars of lentil (Lens culinaris), local Pardina Verde Rayada lentil (PVRL), and commercial Pardina lentil (PL) in terms of the productivity and nutritional composition ...
Mohammad Abdullah   +4 more
wiley   +1 more source

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