The Journal of Physiology, EarlyView.Abstract figure legend Ten older healthy male adults underwent 10 days of bed rest. Vastus lateralis muscle biopsies were collected at baseline (PRE) and after 10 days of bed rest (BR10), and mitochondrial adaptations were assessed using an integrative approach combining respirometry, protein analyses, RNA sequencing and transmission electron ...
Evgeniia Motanova +16 more
wiley +1 more source
Prehospital Adenosine Diphosphate Receptor Blocker Use, Culprit Artery Flow, and Mortality in STEMI: The MADDEC Study. [PDF]
Clin Drug Investig, 2021 Hautamäki M +7 more
europepmc +1 more source
Poly (adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibitors as maintenance therapy in women with newly diagnosed ovarian cancer: a systematic review and meta-analysis. [PDF]
Arch Gynecol Obstet, 2021 Cheng H, Yang J, Liu H, Xiang Y.
europepmc +1 more source
Biomedical Chromatography, Volume 40, Issue 10, October 2026.ABSTRACT Deoxyuridine (dUrd) is often misincorporated into genomic DNA in cancer patients receiving antimetabolite chemotherapy. This activates base excision repair and recruits ataxia telangiectasia‐mutated and Rad3‐related (ATR), which coordinates DNA repair with nucleotide metabolism by facilitating ribonucleotide reductase (RNR) activity ...
Joshua J. Deppas +5 more
wiley +1 more source
Kinetic and Static Analysis of Poly-(Adenosine Diphosphate-Ribose) Polymerase-1-Targeted 18F-Fluorthanatrace PET Images of Ovarian Cancer. [PDF]
J Nucl Med, 2022 Young AJ +14 more
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Acta Physiologica, Volume 242, Issue 10, October 2026.ABSTRACT Aim The Na,K‐ATPase is important for energy demanding cellular processes, including essential components of substrate metabolism and metabolic flexibility. Mice heterozygous for the hemiplegic migraine‐related mutation, G301R, of the Na,K‐ATPase α2 isoform (α2+/G301R) demonstrated altered metabolism in the heart.
Christian Staehr +11 more
wiley +1 more source
Extracellular Adenosine Diphosphate Stimulates CXCL10-Mediated Mast Cell Infiltration Through P2Y1 Receptor to Aggravate Airway Inflammation in Asthmatic Mice. [PDF]
Front Mol Biosci, 2021 Gao YY, Gao ZY.
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The Crosstalk Between Diabetes and Alzheimer's Disease: A Molecular Perspective
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.Increasing evidence indicates an association between type 2 diabetes mellitus and Alzheimer’s disease, contributing to the proposed concept of AD as “type 3 diabetes.” Shared biological features such as impaired insulin signaling, chronic inflammation, mitochondrial dysfunction, and oxidative stress have been observed in both T2DM and AD.
Deniz Catakli +3 more
wiley +1 more source
Tumor treating fields combined with a poly (adenosine diphosphate-ribose) polymerase inhibitor during radiotherapy for rapidly progressing IDH-wildtype diffuse astrocytoma: a case report. [PDF]
J Int Med Res, 2021 Wang Z, Ren Y, Du F, Sun Y, Jiang W.
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