Aging Cell, EarlyView.We show that genetic and pharmacological inhibition of the metabotropic glutamate receptor, DmGluRA extends Drosophila lifespan, improves stress tolerance and alters early‐life locomotion. Several markers indicative of reduced ribosomal biogenesis, a hallmark of longevity, were also detected in these flies.
Cui Guan +4 more
wiley +1 more source
36 degree step size of proton-driven c-ring rotation in FoF1-ATP synthase [PDF]
arXiv, 2009 Synthesis of the biological "energy currency molecule" adenosine triphosphate ATP is accomplished by FoF1-ATP synthase. In the plasma membrane of Escherichia coli, proton-driven rotation of a ring of 10 c subunits in the Fo motor powers catalysis in the F1 motor. While F1 uses 120 degree stepping, Fo models predict a step-by-step rotation of c subunits
arxiv
Programmed death ligand 1, poly adenosine diphosphate ribose polymerase, and vascular endothelial growth factor receptor inhibition: a potential combination regimen for targeting triple-negative breast cancer? [PDF]
Int J Surg, 2023 Abdul Wahid M +5 more
europepmc +1 more source
Role of the phosphocreatine system on energetic homeostasis in skeletal and cardiac muscles
Einstein (São Paulo)Adenosine triphosphate is the present energy currency in the body, and is used in various cellular and indispensable processes for the maintenance of cell homeostasis.
Lucas Guimarães-Ferreira
doaj +1 more source
Aging Cell, EarlyView.While the etiology of race differences in mobility is multifactorial, our data indicate that muscle mitochondrial respiration and cardiorespiratory fitness may contribute to the slower walking speed of individuals who identify as Black compared to White.
Paul M. Coen +12 more
wiley +1 more source
Do Not Forget Poly (Adenosine Diphosphate-Ribose) Polymerase Inhibitors in Ovarian Carcinosarcoma. [PDF]
Cureus, 2022 Magalhães D, Bartosch C, Abreu MH.
europepmc +1 more source
Effects of inorganic ions and of plasma proteins on the aggregation of blood platelets by adenosine diphosphate [PDF]
, 1964 G. V. R. Born, Michael Cross
openalex +1 more source
Risk of stroke accompanying alcohol consumption with or without single‐occasion drinking
Alcohol, Clinical and Experimental Research, EarlyView.Previous studies on alcohol and stroke have highlighted several concerns. Notably, the conventional categorization based on average consumption, which categorizes both those who consume 20 g/day of alcohol daily and those who engage in risky single‐occasion drinking (RSOD) only on weekends into low drinkers, makes it difficult to account for ...
Midori Takada +12 more
wiley +1 more source
Development of Carbon-Fiber Electrodes Modified for Electrochemical ATP Detection [PDF]
arXiv, 2018 Adenosine triphosphate (ATP) is a highly energetic molecule used as a coenzyme in the transfer of chemical energy required for the continuation of cellular metabolism. In addition, extracellular ATP has an important role in cell-to-cell communication in immune, nervous and vascular systems.
arxiv
Adenosine Diphosphate Requirement in the Creatine Phosphate-Induced Contraction of the Glycerinated Rabbit Psoas [PDF]
, 1962 William Cohen +2 more
openalex +1 more source