Results 171 to 180 of about 90,132 (350)
Molecular diagnostic testing identified mCRPC patients with BRCA mutations eligible for targeted therapies. Testing success is often contingent on the quality of tissue handling and laboratory processing techniques to minimize DNA degradation and suboptimal sequencing data quality.
Arun A. Azad+4 more
wiley +1 more source
Poly Adenosine Diphosphate-Ribose Polymerase (PARP) Inhibitors in Pancreatic Cancer. [PDF]
Sunkara T+5 more
europepmc +1 more source
Inorganic polyphosphate (polyP) is a linear polymer containing tens to hundreds of orthophosphate residues linked by high‐energy phosphoanhydride bonds. PolyP promotes osteocalcification and bone mineralization in both mouse and human osteoblastic cells.
Kaori Tsutsumi, Tatsuya Sasase
doaj +1 more source
The adenylate kinase of human plasma, erythrocytes and platelets in relation to the degradation of adenosine diphosphate in plasma [PDF]
RJ HASLAM, D. C. B. Mills
openalex +1 more source
This study investigates the role of mitochondrial fission in keratinocyte apoptosis in blister fluid‐derived exosomes from patients with SJS/TEN, erythema multiforme, and in healthy individuals. Galectin‐7 is upregulated in exosomes of patients with SJS/TEN and shows a correlation with disease severity.
Chen Zhang+16 more
wiley +1 more source
Accumulation of poly (adenosine diphosphate-ribose) by sustained supply of calcium inducing mitochondrial stress in pancreatic cancer cells. [PDF]
Jeong KY, Sim JJ, Park M, Kim HM.
europepmc +1 more source
Detection and determination of adenosine diphosphate and related substances in plasma [PDF]
D.C. Ireland, D. C. B. Mills
openalex +1 more source
Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs+12 more
wiley +1 more source
KINETIC STUDIES OF THE REVERSE REACTION CATALYSED BY ADENOSINE TRIPHOSPHATE-CREATINE PHOSPHOTRANSFERASE. THE INHIBITION BY MAGNESIUM IONS AND ADENOSINE DIPHOSPHATE [PDF]
JF Morrison, W.J. O’Sullivan
openalex +1 more source
Graph‐based algorithms that enable efficient computations of all H‐bonds present in structures in entire datasets allow us to dissect H‐bond fingerprints that characterize distinct GPCRs and the structures sampled along their activation. Abstract Changes in structure and dynamics elicited by agonist ligand binding at the extracellular side of G protein
Éva Bertalan+3 more
wiley +1 more source