Results 241 to 250 of about 288,808 (285)
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Selected cardiovascular effects of adenosine diphosphate
American Heart Journal, 1970Abstract Six intact dogs were studied before, during, and after an 8 minute infusion of ADP, 0.4 mg./min./Kg. There was a significant decrease in aortic pressure, systemic vascular resistance and platelets, and an increase in cardiac output, central blood volume, stroke volume, heart rate, and pulmonary artery pressure.
Richard E. Brashear +2 more
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Synthesis and characterization of 2'-adenosine diphosphate and 3'-adenosine diphosphate
19652'-adenosine diphosphate and 3'-adenosine diphosphate were made from the corresponding unprotected nucleoside monophosphates using phosphoramidic acid. This synthesis of the pyrophosphate link was stimulated by pyridine. Both compounds were more labile than 5'-ADP, and they were shown to degrade by two separate routes.
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Poly(adenosine diphosphate ribose)
1973Publisher Summary This chapter discusses that incorporation of radioactivity of (adenine- 14 C) ATP into the acid insoluble material in a nuclear preparation from hen liver is enhanced at least 1000-fold by the presence of NMN. It is confirmed that this stimulation: using a nuclear preparation from rat liver.
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Adenosine Diphosphate, Adenosine Triphosphate
1955The increasing importance for animals and bacteria of adenosine diphosphate (ADP) and adenosine triphosphate (ATP) in energy-transfer mechanisms involving such widely diverse processes as muscular contraction, nerve conduction, fire fly luminescence, coenzyme syntheses, tumor growth, polysaccharide synthesis and many other key reactions (McElroy and ...
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Variability of platelet responses to adenosine diphosphate
Thrombosis Research, 2013Comment on: Decreased platelet miR-223 expression is associated with high on-clopidogrel platelet reactivity, Shi R, Ge L, Zhou X, Ji WJ, Lu RY, Zhang YY, Zeng S, Liu X, Zhao JH, Zhang WC, et al. Thromb Res.
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The amount and compartmentalization of adenosine diphosphate in muscle
Biochimica et Biophysica Acta, 1962Abstract A fraction of the ADP in muscle was extracted with aqueous ethanol at low temperature, and if the extractanta contained citrate there was no loss of ADP during or after the extraction. The quantity so determined in this work averaged about 0.25 μmole/g; there was some indication, but no explicit proof, that this figure should be corrected ...
W.F.H.M. Mommaerts +2 more
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A 5′-amino analog of adenosine diphosphate
Biochemical and Biophysical Research Communications, 1973Abstract The synthesis and properties of the 5′-amino analog of adenosine diphosphate are described. The 5′-amino-5′-deoxyadenosine 5′-N-diphosphate (NADP) is prepared from the previously described aminonucleoside triphosphate by the hexokinase catalyzed transfer of the terminal phosphoryl to glucose. The NADP is stable in neutral or basic media, and
John S. Wilkes +2 more
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Studies on poly(adenosine diphosphate-ribose)
Archives of Biochemistry and Biophysics, 1971Abstract Hydroxylapatite column chromatography was used for purification of poly (ADP-Rib). With an increasing concentration gradient of phosphate buffer (pH 6.8) RNA, DNA, and poly (ADP-Rib) with a chain of 17–18 ADP-ribose units were eluted successively.
Naoko Yoshimura +4 more
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Seminars in Thrombosis and Hemostasis, 2005
Ticlopidine and clopidogrel belong to the same chemical family of thienopyridine adenosine diphosphate (ADP)-receptor antagonists. They have shown their efficacy as platelet antiaggregant and antithrombotic agents in many animal models, both ex vivo and ...
P. Savi, J. Herbert
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Ticlopidine and clopidogrel belong to the same chemical family of thienopyridine adenosine diphosphate (ADP)-receptor antagonists. They have shown their efficacy as platelet antiaggregant and antithrombotic agents in many animal models, both ex vivo and ...
P. Savi, J. Herbert
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Binding of Adenosine Diphosphate to Turkey Thrombocytes
Pathophysiology of Haemostasis and Thrombosis, 1982Adenosine diphosphate (ADP) caused rapid and reversible aggregation of turkey thrombocytes, as determined by optical and microscopical examination. To investigate the binding of ADP to these cells, turkey thrombocyte-rich plasma was incubated with ADP-8–<sup>14</sup>C or ADP-3–<sup>3</sup>H and with human serum albumin labeled ...
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