Results 271 to 280 of about 105,286 (352)

Damage‐associated molecular patterns and coagulation

open access: yesBritish Journal of Haematology, Volume 208, Issue 1, Page 54-57, January 2026.
Injured cells release damage‐associated molecular patterns (DAMPs), which promote clot formation by activating coagulation, inflammation and immune pathways. Targeting these immunothrombotic mechanisms, via DAMPs, offers new opportunities for diagnosis and therapy in thromboinflammatory disease.
Jun Yong, Cheng‐Hock Toh
wiley   +1 more source

Comparative metabolomic and transcriptomic analysis of 2D and 3D mesenchymal stem cell cultures for improved therapeutic applications

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 2, Page 379-392, January 2026.
Comparative metabolomic and transcriptomic profiling reveals distinct metabolic shifts and reduced proliferation in 3D MSC spheroids, providing insights to optimise MSC‐based therapies. Abstract Background and Purpose Mesenchymal stem cells (MSCs) are used widely in regenerative medicine due to their multipotency and immunomodulatory properties ...
Manju Shrestha   +7 more
wiley   +1 more source

Lexicon for Clonal Hematopoiesis in Liquid Biopsy

open access: yesClinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT Historically, clonal hematopoiesis (CH) has been recognized as a confounder of cell‐free DNA (cfDNA) testing. Recent evidence now demonstrates the role of CH as a risk factor in health, generating distinct sources of cfDNA that can be leveraged for liquid biopsy diagnostics.
Robert Tell   +21 more
wiley   +1 more source

Kinetic and mutational studies of the adenosine diphosphate ribose hydrolase from Mycobacterium tuberculosis. [PDF]

open access: yesJ Bioenerg Biomembr, 2016
O'Handley SF   +6 more
europepmc   +1 more source

Assessing the interaction of the UCP system and fatty acids on epicardial adipose tissue mitochondrial respiration

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Epicardial adipose tissue (EAT) demonstrates higher mitochondrial activity than subcutaneous fat (SAT), particularly in NADH‐ and FAO‐linked oxidative phosphorylation (OXPHOS). While EAT expresses more UCP1, its inhibition by GDP minimally affects respiration, especially in FAO pathways, suggesting UCP1‐independence. Diabetes mellitus (DM) and coronary
Diana Santos   +12 more
wiley   +1 more source

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