Results 271 to 280 of about 105,286 (352)
Damage‐associated molecular patterns and coagulation
Injured cells release damage‐associated molecular patterns (DAMPs), which promote clot formation by activating coagulation, inflammation and immune pathways. Targeting these immunothrombotic mechanisms, via DAMPs, offers new opportunities for diagnosis and therapy in thromboinflammatory disease.
Jun Yong, Cheng‐Hock Toh
wiley +1 more source
Canine platelets express functional Toll-like receptor-4: lipopolysaccharide-triggered platelet activation is dependent on adenosine diphosphate and thromboxane A2 in dogs. [PDF]
Li RHL, Nguyen N, Tablin F.
europepmc +1 more source
Comparative metabolomic and transcriptomic profiling reveals distinct metabolic shifts and reduced proliferation in 3D MSC spheroids, providing insights to optimise MSC‐based therapies. Abstract Background and Purpose Mesenchymal stem cells (MSCs) are used widely in regenerative medicine due to their multipotency and immunomodulatory properties ...
Manju Shrestha +7 more
wiley +1 more source
The inhibitory activity of ginsenoside Rp4 in adenosine diphosphate-induced platelet aggregation. [PDF]
Son YM, Jeong DH, Park HJ, Rhee MH.
europepmc +1 more source
Lexicon for Clonal Hematopoiesis in Liquid Biopsy
ABSTRACT Historically, clonal hematopoiesis (CH) has been recognized as a confounder of cell‐free DNA (cfDNA) testing. Recent evidence now demonstrates the role of CH as a risk factor in health, generating distinct sources of cfDNA that can be leveraged for liquid biopsy diagnostics.
Robert Tell +21 more
wiley +1 more source
Kinetic and mutational studies of the adenosine diphosphate ribose hydrolase from Mycobacterium tuberculosis. [PDF]
O'Handley SF +6 more
europepmc +1 more source
Epicardial adipose tissue (EAT) demonstrates higher mitochondrial activity than subcutaneous fat (SAT), particularly in NADH‐ and FAO‐linked oxidative phosphorylation (OXPHOS). While EAT expresses more UCP1, its inhibition by GDP minimally affects respiration, especially in FAO pathways, suggesting UCP1‐independence. Diabetes mellitus (DM) and coronary
Diana Santos +12 more
wiley +1 more source

