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Background The regeneration of injured tissues remains a major clinical challenge. Among emerging biomaterials, collagen with platelet‐rich plasma (PRP) or platelet‐rich fibrin (PRF) showed promising outcomes, individually and in combination. Objective To systematically review clinical evidence on the efficacy, applications, and safety of PRP/PRF and ...
Nunzia Gallo +6 more
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The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease
Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira +2 more
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Abstract Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a dismal prognosis, largely because of late‐stage diagnosis and therapeutic resistance. PDAC incidence has been rising, with modifiable and non‐modifiable risk factors contributing to disease development.
Alessandro Mannucci, Ajay Goel
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Abstract Although poly(adenosine diphosphate‐ribose) polymerase inhibitors (PARPis) and bevacizumab were approved as first‐line maintenance for advanced ovarian cancer (OC), evidence comparing this combination with PARPi monotherapy, especially in BRCA‐mutated/homologous recombination‐deficient (HRD) patients, is lacking.
Lingying Wu +56 more
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Structural flexibility of the nicotinamide group of NADH in butanol dehydrogenase YqdH from Fusobacterium nucleatum. [PDF]
Bai X, Nam KH, Xu Y.
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The pyrophosphorylysis of adenosine diphosphate glucose and adenosine diphosphate mannose
Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects, 1964Abstract 1. 1. The biosynthesis of adenosine diphosphate glucose and adenosine diphosphate mannose from adenosine triphosphate and respectively glucose 1-phosphate and mannose 1-phosphate has been observed in extracts from mammalian tissues. The reaction is reversible in the presence of the nucleoside diphosphate sugar and pyrophosphate. 2. 2.
H, VERACHTERT, S T, BASS, R G, HANSEN
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Adenosine diphosphate and adenosine monophosphate: enzymatic spectrophotometric determination
The Journal of Nutritional Biochemistry, 1990Determination enzymatique et spectrophotometrique de l'adenosine diphosphate (ADP) et de l'adenosine monophosphate (AMP). Phosphorylation de l'ADP par une pyruvate kinase puis reduction du pyruvate en presence de NADH. Mesure de la consommation de NADH au spectrophotometre a 340 nm.
K, Tornheim, V, Schultz
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Poly(adenosine diphosphate ribose)
1982Publisher Summary This chapter discusses the higher-order structure of poly(adenosine diphosphate ribose) [poly(ADPR)], poly(ADPR) polymerase purification and its properties, and molecular mechanisms of histone- and elongation-factor (EF-2)-ADP-ribosylation.
P, Mandel, H, Okazaki, C, Niedergang
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