Results 31 to 40 of about 287,572 (191)

Cyclic Adenosine Diphosphate Ribose Activates Ryanodine Receptors, whereas NAADP Activates Two-pore Domain Channels*

open access: yesJournal of Biological Chemistry, 2011
The mechanism by which cyclic adenosine diphosphate ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate (NAADP) mobilize intracellular Ca2+ stores remains controversial.
O. Ogunbayo   +6 more
semanticscholar   +1 more source

Enzymid dephosphorylation of adenosine diphosphate phosphoglyceric acid [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects, 1964
Abstract An enzyme from muscle which acts on adenosine diphosphate phosphoglyceric acid and leads to the hydrolysis of the phosphate group at the 2-position of the glyceric acid moiety has been studied. The enzyme is strongly stimulated by inorgamoc pyrophosphate. This action is very specific. The enzyme also acts on 2,3-diphosphoglycerate.
Zancan, Glaci T.   +2 more
openaire   +4 more sources

Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase [PDF]

open access: yes, 2007
This research was supported by the German Academic Exchange Service (DAAD), the Wellcome Trust (TKS and WNH as Trust Senior Research fellows), the Biotechnology and Biological Science Research Council (Structural Proteomics of Rational Targets) and the ...
Hunter, William N.   +2 more
core   +2 more sources

P2 purinoceptors signaling in fibroblasts of rat subcutaneous tissue [PDF]

open access: yes, 2011
Mestrado em Biologia Molecular e CelularO tecido conjuntivo parece estar envolvido na génese de diversas condições patológicas. O aumento da rigidez do tecido conjuntivo, resultante da fibrose, pode constituir um factor importante no mecanismo patogénico
Reis, Carla Patrícia da Silva e Sousa
core   +1 more source

ATPase mechanism of the 5'-3' DNA helicase, RecD2: evidence for a pre-hydrolysis conformation change [PDF]

open access: yes, 2013
The superfamily 1 helicase, RecD2, is a monomeric, bacterial enzyme with a role in DNA repair, but with 5'-3' activity unlike most enzymes from this superfamily. Rate constants were determined for steps within the ATPase cycle of RecD2 in the presence of
Bae   +34 more
core   +1 more source

Diabetes mellitus and ischemic heart disease. the role of ion channels [PDF]

open access: yes, 2018
Diabetes mellitus is one the strongest risk factors for cardiovascular disease and, in particular, for ischemic heart disease (IHD). The pathophysiology of myocardial ischemia in diabetic patients is complex and not fully understood: some diabetic ...
De Marchis, Marialaura   +8 more
core   +2 more sources

Can adenine nucleotides predict primary nonfunction of the human liver homograft? [PDF]

open access: yes, 1994
Sixty-eight primary liver grafts were analyzed to see whether adenine nucleotides (AN: ATP, ADP, and AMP) or purine catabolites (PC: adenosine, inosine, hypoxanthine, and xanthine) of tissue or effluent can predict primary graft nonfunction.
Bronsther, O   +8 more
core   +1 more source

Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells [PDF]

open access: yes, 2008
Purinergic signalling is important both in short-term control of vascular tone and in longer-term control of cell proliferation, migration and death involved in vascular remodelling.
Burnstock, G
core  

Platelets and galectins [PDF]

open access: yes, 2014
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core   +1 more source

Biochemical Effects of Exercise on a Fasciocutaneous Flap in a Rat Model. [PDF]

open access: yes, 2017
Importance: An overwhelming amount of data suggest that cardiovascular exercise has a positive effect on the mind and body, although the precise mechanism is not always clear.
Aksamitiene, Edita   +8 more
core   +3 more sources

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