Results 31 to 40 of about 103,074 (260)

Nucleotides: Structure and Properties [PDF]

, 2005
Nucleotides consist of a nitrogen-containing base, a five-carbon sugar, and one or more phosphate groups. Cells contain many types of nucleotides, which play a central role in a wide variety of cellular processes, including metabolic regulation and the ...
Bowater, RP
core   +1 more source

Antiplatelet and Antithrombotic Activities of Non-Steroidal Anti-Inflammatory Drugs Containing an N-Acyl Hydrazone Subunit

Molecules, 2014
Nonsteroidal anti-inflammatory drugs (NSAIDs) 1–5 containing an N-acyl hydrazone subunit were prepared and their antiplatelet and antithrombotic activities assessed in vitro and in vivo.
Rafael Consolin Chelucci, Luiz Antônio Dutra, Maria Elisa Lopes Pires, Thais Regina Ferreira de Melo, Priscila Longhin Bosquesi, Man Chin Chung, Jean Leandro dos Santos   +6 more
doaj   +1 more source

ANALYSIS OF THE STATE OF PLATELET AGGREGATION IN PREGNANT WOMEN WITH THROMBOPHILIA AND BURDENED OBSTETRIC HISTORY

Східноукраїнський медичний журнал, 2021
The analysis of platelet aggregation in pregnant women with thrombophilia and burdened obstetric history was performed. It has been determined that the development of adverse effects of pregnancy is significantly influenced by conditions such as ...
Olha I. Zalyubovska, Valeriya V. Hryshchenko   +1 more
doaj   +1 more source

Adenosine diphosphate inhibits the serotonin transporter

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1996
Adenosine 5'-diphosphate (ADP) caused rapid and significant reductions in the rates of [3H]serotonin uptake observed for human platelets, human platelet vesicles, and rat brain synaptic vesicles. Estimated Vmax values in platelets (N = 15). platelet vesicles (N = 3), and synaptic vesicles (N = 3) exposed to 100 microM ADP were 42.3 +/- 11.4%, 78.8 ...
William C. Horne, Jing Xia Yang, George M. Anderson, Laura M. Hall   +3 more
openaire   +3 more sources

Yeast Phosphoramidate-Adenosine Diphosphate Phosphotransferase [PDF]

Journal of Biological Chemistry, 1968
Abstract An enzyme, phosphoramidate-ADP phosphotransferase, has been isolated from dried bakers' yeast. We have previously shown that phosphoramide, N-phosphorylglycine, and N-phosphohistidine can act as phosphate donors. Phosphoiodohistidine was shown also to function as a phosphate donor and the enzyme was stereospecific for the l form of this ...
Henry I. Nakada, Michael J. Dowler
openaire   +2 more sources

Impaired cardiac and skeletal muscle bioenergetics in children, adolescents, and young adults with Barth syndrome [PDF]

, 2017
Barth syndrome (BTHS) is an X‐linked condition characterized by altered cardiolipin metabolism and cardioskeletal myopathy. We sought to compare cardiac and skeletal muscle bioenergetics in children, adolescents, and young adults with BTHS and unaffected
Altschuld, American College of Sports Medicine, Bahi, Barth, Bashir, Bione, Bissler, Cade, Cade, Chance, Chance, Conway, Edwards, El-Sharkawy, Gomez, Gonzalvez, Hiona, Hom, Hudsmith, Ingwall, Kemp, Kemp, Kemp, Kemp, Kushmerick, Lang, Lanza, Lanza, Larson-Meyer, Layec, Liu, Matthews, Meyer, Meyer, Minotti, Naressi, Nascimben, Neubauer, Powers, Ratel, Roussel, Sapega, Schlame, Sgobbo, Smith, Spencer, Spencer, Spoladore, Takahashi, Taylor, Taylor, Thaveau, Thompson, Tonson, Vanhamme, Wang, Wasserman, Waters, Xu, Yao, Zhang, Zoll   +61 more
core   +2 more sources

The role of free nucleotides in heart failure

Кардиоваскулярная терапия и профилактика
Aim. To assess the potential of studying the plasma level of free nucleotides as additional biomarkers of heart failure (HF) taking into account the clinical and paraclinical data of the patient, and to analyze its change during therapy.Material and ...
E. V. Kolesnikova, O. V. Myachina, A. N. Pashkov, A. A. Pashkova   +3 more
doaj   +1 more source

Assessment of the functional activity of platelets in chronic kidney disease stage 5D

Alʹmanah Kliničeskoj Mediciny, 2018
Rationale: Thromboembolic complications in patients on hemodialysis have a  significant impact on the duration and quality of life. Aim: To study the functional status of platelets in chronic kidney disease stage 5D (CKD-5D).
K. N. Zelenin, A. M. Esayan, A. Sh. Rumyantsev   +2 more
doaj   +1 more source

Free Adenosine Diphosphate as an Intermediary in the Phosphorylation by Creatine Phosphate of Adenosine Diphosphate Bound to Actin

Journal of Biological Chemistry, 1967
Abstract Pretreatment of adenosine diphosphate-G-actin solutions with apyrase results in a marked decrease in their rate of polymerization at 0° induced by KCl, creatine phosphate, and creatine kinase. In contrast, apyrase has no effect on the rate of polymerization of ATP-G-actin.
B. Nagy, J.J. West, John Gergely
openaire   +3 more sources

Baicalin inhibited PANX-1/P2Y6 signaling pathway activation in porcine aortic vascular endothelial cells infected by Glaesserella parasuis

Heliyon
Glaesserella parasuis can induce endothelial barrier damage in piglets, although the mechanism by which this pathogen triggers inflammatory damage remains unclear. Baicalin possesses anti-inflammatory and anti-oxidant activities.
Shulin Fu, Xinyue Tian, Chun Peng, Dan Zhang, Linglu Zhou, Yuzhen Yuan, Jing He, Ling Guo, Yinsheng Qiu, Chun Ye, Yu Liu, Bingbing Zong   +11 more
doaj   +1 more source