Results 61 to 70 of about 163,297 (275)
A depletable pool of adenosine in area CA1 of the rat hippocampus [PDF]
, 2001 Adenosine plays a major modulatory and neuroprotective role in the mammalian CNS. During cerebral metabolic stress, such as hypoxia or ischemia, the increase in extracellular adenosine inhibits excitatory synaptic transmission onto vulnerable neurons via
Darren Caldwell +9 more
core +1 more source
Advanced Science, EarlyView.This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang +5 more
wiley +1 more source
Атеротромбоз, 2017 The article presents a comparative evaluation of the current clinical angiographic scales in the risk stratification for patients with stable coronary artery disease undergoing elective percutaneous coronary interventions.
E. S. Novikova +7 more
doaj +1 more source
Yeast Phosphoramidate-Adenosine Diphosphate Phosphotransferase
Journal of Biological Chemistry, 1968 Abstract An enzyme, phosphoramidate-ADP phosphotransferase, has been isolated from dried bakers' yeast. We have previously shown that phosphoramide, N-phosphorylglycine, and N-phosphohistidine can act as phosphate donors. Phosphoiodohistidine was shown also to function as a phosphate donor and the enzyme was stereospecific for the l form of this ...
M J, Dowler, H I, Nakada
openaire +2 more sources
Role of cGMP as second messenger of adenosine in the inhibition of renin release [PDF]
, 1988 Adenosine is known to be a potent inhibitor of renin release from the kidneys. The aim of this study was to investigate the transmembrane signalling avenue that the second messenger of adenosine causes inhibition of renal renin release.
Kurtz, Armin +5 more
core +1 more source
Angewandte Chemie, EarlyView.Eine klickbare, photogeschützte 5′‐Kappe (CyCliCap) zur Herstellung von zyklischer, Click‐Cap enthaltender mRNA (Cyclic Click Cap‐mRNA), die bis zur Bestrahlung beachtlich stabil und translational stumm ist, ermöglicht die Aktivierung der Translation in Zellen zu späten Zeitpunkten mittels Lichts. ZUSAMMENFASSUNG mRNA ist eine neue Impfstofftechnologie
Bayram Terzi +6 more
wiley +1 more source
Identification of Key Metabolites for Acute Lung Injury in Patients with Sepsis
Iranian Journal of Public Health, 2019 Background: The study aimed to detect critical metabolites in acute lung injury (ALI). Methods: A comparative analysis of microarray profile of patients with sepsis-induced ALI compared with sepsis patients with was conducted using bioinformatic tools
Pei-Quan WANG +4 more
doaj +1 more source
Adenosine diphosphate inhibits the serotonin transporter
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1996 Adenosine 5'-diphosphate (ADP) caused rapid and significant reductions in the rates of [3H]serotonin uptake observed for human platelets, human platelet vesicles, and rat brain synaptic vesicles. Estimated Vmax values in platelets (N = 15). platelet vesicles (N = 3), and synaptic vesicles (N = 3) exposed to 100 microM ADP were 42.3 +/- 11.4%, 78.8 ...
Anderson, George M. +3 more
openaire +2 more sources
PLoS Neglected Tropical Diseases, 2022 Background Pyruvate kinase widely exists in many parasites and plays an important role in the energy production for the parasites. Pyruvate kinase might be a potential drug target for killing the parasites.
Wen Wen Yue +8 more
doaj
Modulators of Ion Transport in Nasal Polyps: An Measurement of Short-Circuit Current [PDF]
Clinical and Experimental Otorhinolaryngology, 2008 ObjectivesTo examine possible modulators of the ion transport through the apical membrane of the nasal polyps.MethodsThe study was conducted using the freshly-excised nasal polyps from the patients with chronic sinusitis.
Jun Ho Lee +3 more
doaj +1 more source