Naked‐Eye Visual Warning of ppmv‐Level Fault‐Free Humidity Upper Limit
Advanced Science, EarlyView.In this study, based on the urgent need in many critical fields for ppmv‐level fault‐free humidity upper limit (ppmv‐FFHUL) monitoring, an innovative threshold gated humidity sensing technology was developed. It exhibits superior portability (as thin and light as paper) and highly economic feature (without auxiliary instruments at all), and can achieve
Xiaoyan Wei +4 more
wiley +1 more source
Advanced Science, EarlyView.A universal ROR1 antibody‐engineered lipid nanoparticle (LNP) is constructed by sequential drug encapsulation and antibody conjugation. The LNP not only enables enhanced chemotherapeutic efficiency by targeting drug delivery and precise localization of deep‐seated tumors through NIR‐II fluorescence imaging, but also remodels immunosuppressive TME ...
Yeneng Dai +12 more
wiley +1 more source
Fructose Potentiates Bone Loss and Marrow Adipose Tissue Accumulation by Inhibiting Adenosine 5ʹ-Monophosphate-Activated Protein Kinase in Mesenchymal Stem Cells [PDF]
Ziqi Yan +6 more
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Inactivation of isocitrate dehydrogenase kinase/phosphatase by 5′‐[p‐(fluorosulfonyl)benzoyl]adenosine is not due to the labeling of the invariant lysine residue found in the protein kinase family [PDF]
, 1998 C. Oudot +6 more
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Advanced Science, EarlyView.Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang +7 more
wiley +1 more source
Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment
Advanced Science, EarlyView.This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang +7 more
wiley +1 more source
Adenosine kinase from L1210 cells. Purification and some properties of the enzyme.
, 1980 C.H. Chang, R W Brockman, L. Lee Bennett
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Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling
Advanced Science, EarlyView.Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu +20 more
wiley +1 more source
Seasonal changes in adenosine kinase in tanycytes of the Arctic ground squirrel (Urocitellus parryii). [PDF]
J Chem Neuroanat, 2021 Frare C, Drew KL.
europepmc +1 more source