Results 171 to 180 of about 745,257 (254)

A monomer-dimer switch modulates the activity of plant adenosine kinase. [PDF]

J Exp Bot
Kopečný DJ, Vigouroux A, Bělíček J, Kopečná M, Končitíková R, Friedecká J, Mik V, Supíková K, Humplík JF, Le Berre M, Plancqueel S, Strnad M, von Schwartzenberg K, Novák O, Moréra S, Kopečný D.   +15 more
europepmc   +1 more source

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Adenosine Kinase: An Epigenetic Modulator and Drug Target. [PDF]

J Inherit Metab Dis
Peter-Okaka U, Boison D.
europepmc   +1 more source

Adenosine kinase is critical for neointima formation after vascular injury by inducing aberrant DNA hypermethylation. [PDF]

Cardiovasc Res, 2021
Wang Y, Xu Y, Yan S, Cao K, Zeng X, Zhou Y, Liu Z, Yang Q, Pan Y, Wang X, Boison D, Su Y, Jiang X, Patel VS, Fulton D, Weintraub NL, Huo Y.   +16 more
europepmc   +1 more source

Adenosine monophosphate–activated protein kinase activation is associated with suppression of NLRP3 inflammasome–mediated neuroinflammation in a weight‐drop model of traumatic brain injury in Sprague–Dawley rats

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the study's schematic model. Adenosine monophosphate–activated protein kinase (AMPK) activators exhibited neuroprotection in the weight‐drop model of traumatic brain injury by improving cognition and regulating oxidative stress, microglial activation, and nucleotide‐binding oligomerization domain, leucine‐rich repeat,
Triveni Kodi, Paka Sravan Kumar, Krishnadas Nandakumar, Anoop Kishore   +3 more
wiley   +1 more source

A novel molecular switch in plant growth: how adenosine kinase activity modulates plant development and growth pathways. [PDF]

J Exp Bot
Watson KM.
europepmc   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Adenosine kinase protects against acetaminophen-induced acute liver injury by activating autophagy in hepatocytes. [PDF]

Cell Biol Toxicol
Zhang C, Liu X, Liu X, Hua R, Liu H, Ma J, Zou D, Wang G, Yuan Q, Wang B, Wei S, Chen Y.   +11 more
europepmc   +1 more source

Adenosine Kinase Expression in the Frontal Cortex in Schizophrenia. [PDF]

Schizophr Bull, 2020
Moody CL, Funk AJ, Devine E, Devore Homan RC, Boison D, McCullumsmith RE, O'Donovan SM.   +6 more
europepmc   +1 more source

Adenosine kinase inhibition protects mice from abdominal aortic aneurysm via epigenetic modulation of VSMC inflammation. [PDF]

Cardiovasc Res
Xu J, Liu Z, Yang Q, Ma Q, Zhou Y, Cai Y, Zhao D, Zhao G, Lu T, Ouyang K, Hong M, Kim HW, Shi H, Zhang J, Fulton D, Miller C, Malhotra R, Weintraub NL, Huo Y.   +18 more
europepmc   +1 more source