Results 231 to 240 of about 165,863 (254)
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Adenosine kinase inhibitors.

Current pharmaceutical design, 1999
Adenosine (ADO) is an endogenous modulator of intercellular signaling that provides homeostatic reductions in cell excitability during tissue stress and trauma. The inhibitory actions of ADO are mediated by interactions with specific cell-surface G-protein coupled receptors regulating membrane cation flux, polarization, and the release of excitatory ...
E A, Kowaluk, S S, Bhagwat, M F, Jarvis
openaire   +1 more source

Diazepam inhibition of adenosine uptake in the CNS: Lack of effect on adenosine kinase

General Pharmacology: The Vascular System, 1983
1. When tested at concentrations resulting in significant inhibitions of adenosine uptake in brain slices, diazepam and several other benzodiazepines were without effect on brain adenosine kinase. 2. This suggests that the inhibitory effect of the benzodiazepines on adenosine accumulation is at the membrane transport level and not by an inhibition of ...
L P, Davies, J W, Hambley
openaire   +2 more sources

Production of Adenosine and Nucleoside Analogues by an Exchange Reaction Catalyzed by Adenosine Kinase

1995
We have shown previously that rat liver adenosine kinase can catalyze an exchange reaction between adenosine (Ado) and AMP in the absence of ATP (1). This exchange reaction was potently stimulated by ADP. When measured in the absence of added ADP, the exchange could be due to a slight (0.001 %) contamination by ADP of analytical grade AMP (2).
M, Mimouni   +2 more
openaire   +2 more sources

Adenosine kinase

1997
Dietmar Schomburg, Dörte Stephan
openaire   +1 more source

Adenosine kinase inhibitors augment release of adenosine from spinal cord slices

European Journal of Pharmacology, 1996
Thomas D White, Jana Sawynok
exaly  

Adenosine kinase determines the degree of brain injury after ischemic stroke in mice

Journal of Cerebral Blood Flow and Metabolism, 2011
Theresa A Lusardi   +2 more
exaly  

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