Results 131 to 140 of about 95,796 (312)

From In Vitro Efficacy to Long‐Term HbA1c Response for GLP‐1R/GlucagonR Agonism Using the 4GI‐HbA1c Systems Model

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
A combined systems model (4GI‐HbA1c) was developed to predict glucose and HbA1c responses to GLP‐1 and GLP‐1/glucagon receptor agonists using early pharmacokinetic and in vitro efficacy data. Validated with short‐term CGM data, the model accurately predicted 26‐week clinical outcomes for liraglutide and cotadutide, demonstrating its value in supporting
Rolien Bosch, Marcella Petrone, Rosalin Arends, Eric J. G. Sijbrands, Sven Hoefman, Nelleke Snelder   +5 more
wiley   +1 more source

Adenosine Triphosphate: Uridine Monophosphate-Cytidine Monophosphate Phosphotransferase from Tetrahymena pyriformis

, 1969
B. Winfred Ruffner, Elizabeth P. Anderson   +1 more
openalex   +1 more source

Mitochondrial dynamics in autoimmune diseases

Rheumatology &Autoimmunity, EarlyView.
Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma, Cheng Zhang, Jiaqing Liu, Jinyi Ren, Xia Li, Ying Zhao   +5 more
wiley   +1 more source

Biochemical characterization of a unique cytokinin and nucleotide phosphoribohydrolase Lonely Guy protein from Dictyostelium discoideum

Biochemistry and Biophysics Reports
Lonely guy (LOG) proteins are phosphoribohydrolases (PRHs) that are key cytokinin (CK)-activating enzymes in plant and non-plant CK-producing organisms.
Megan M. Aoki, Anna B. Kisiala, Scott C. Farrow, Craig R. Brunetti, Robert J. Huber, R.J. Neil Emery   +5 more
doaj  

Downregulation of cyclic adenosine monophosphate levels in leukocytes of hibernating captive black bears is similar to reported cyclic adenosine monophosphate findings in major depressive disorder. [PDF]

Front Psychiatry, 2023
Tsiouris JA, Flory M.
europepmc   +1 more source

Adenosine 3',5'-cyclic monophosphate and morphology in Neurospora crassa: drug-induced alterations [PDF]

, 1975
William Scott, Bruce Solomon
openalex   +1 more source

Circularly polarized luminescence from supramolecular assemblies based on small molecules

Smart Molecules, EarlyView.
This minireview outlines the recent advances of circularly polarized luminescence (CPL)‐active supramolecular assemblies based on small molecules. It covers fundamental concepts of CPL, typical design strategies of CPL‐active materials—including the assembly of chiral luminophores, the assembly of chiral components and achiral luminophores, and the ...
Xinyu Liu, Xiaoyan Wang, Xiaotao Zhang, Liqiang Li, Yu Wang, Wenping Hu   +5 more
wiley   +1 more source

Adenosine 3‘, 5‘-Monophosphate in Biological Materials

, 1965
R.W. Butcher, Ren-jye Ho, H. C. Meng, Earl W. Sutherland   +3 more
openalex   +1 more source

Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons

Small Science, EarlyView.
This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong, Yanyi Peng, Lingyue Zhang, Bo Xiao, Mengqi Zhang   +4 more
wiley   +1 more source

Effects of Cyclic Adenosine Monophosphate Nanoliposomes on Growth Performance, Gut Development and Microbiota of Broilers. [PDF]

Animals (Basel)
Chen L, Wang L, Huang S, Su G, Jiang S, Yang F, Huang J.   +6 more
europepmc   +1 more source