Results 141 to 150 of about 165,902 (383)
Administration of metformin in clinical medicine; an updated mini-review on current findings [PDF]
Journal of Nephropharmacology, 2018 Metformin is in the biguanide class that has been considered as the treatment for insulin resistance diabetes and polycystic ovarian disease. Many mechanisms have been suggested for it such as inhibition of the mitochondrial respiratory chain and ...
Mahrang Hedaiaty
doaj
Journal of Dairy Science, 2022 : A robust method using HPLC-UV was developed to improve the accuracy and repeatability of a quantitative method to detect 5 nucleotides (cytidine-monophosphate, uridine monophosphate, adenosine monophosphate, guanine monophosphate, and inosine ...
Yuanjia Chen +4 more
doaj
Inhibition of Gastric Erosion Formations in Rats by Adenosine, 5 /-Adenosine Monophosphate and 5 /- Adenosine Diphosphate [PDF]
, 2009 Gastric erosions were induced in rats with indomethacin, 5-hydoxytryptamine (5-HT) or reserpine. Three adenine compounds adenosine, adenosine, 5 /-adenosine monophosphate (AMP) and 5 /- adenosine diphosphate (ADP) were found to protect against the ...
Anosike, CA, Ezekwe, CI, Nwodo, OFC
core +2 more sources
ChemBioChem, EarlyView.In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout +1 more
wiley +1 more source
Efficacy and safety of apremilast and phototherapy versus phototherapy only in psoriasis vulgaris
The Journal of Dermatology, Volume 49, Issue 12, Page 1211-1220, December 2022., 2022 Abstract Phototherapy and apremilast (oral phosphodiesterase‐4 inhibitor) are well‐known in the treatment of moderate to severe psoriasis vulgaris. However, current evidence on the efficacy and safety of their combination is not sufficient. This multicenter, randomized controlled study compared the efficacy and safety between phototherapy as ...
Akimichi Morita +12 more
wiley +1 more source
Coulomb Interaction as the Source of Muscle Force [PDF]
arXiv, 2007 Myosin motor is the machine, which performs mechanical work in the course of adenosine triphosphate molecule hydrolysis and myosin head conformations accompanying this process. For displacement of individual fragments of large molecule relative to each other to arise and work to be performed, force must be born inside protein.
arxiv
The Role of Adenosine Signaling in Headache: A Review
Brain Sciences, 2017 Migraine is the third most prevalent disease on the planet, yet our understanding of its mechanisms and pathophysiology is surprisingly incomplete. Recent studies have built upon decades of evidence that adenosine, a purine nucleoside that can act as a ...
Nathan T. Fried +2 more
doaj +1 more source
ChemBioChem, EarlyView.A human‐derived recognition tag of Pyrococcus horikoshii biotin ligase is fused to the monoclonal antibody trastuzumab at the C‐termini of either light or heavy chain. These fusion antibodies allow for the PhBL‐mediated introduction of desthiobiotin azide and the subsequent attachment of DBCO‐AF488 and DBCO‐Val‐Cit‐PAB‐MMAE via strain‐promoted azide ...
Peter Bitsch +5 more
wiley +1 more source
Journal of Diabetes, Volume 14, Issue 12, Page 806-814, December 2022., 2022 Highlights Metformin activates GDF15 expression, which reduces appetite with induction of weight loss in both diabetic and non‐diabetic patients. GDF15 level is linked and correlated with the progression of diabetic complications including thrombosis, diabetic nephropathy, diabetic neuropathy, and diabetic retinopathy. Abstract Type 2 diabetes mellitus
Hayder M. Al‐kuraishy +8 more
wiley +1 more source
Pilot study of electrochemical reduction of selected nucleotides and double-stranded DNA at pristine micro-/ultrananocrystalline boron-doped diamond electrodes at very negative potentials [PDF]
Pristine polycrystalline boron-doped diamond electrodes (BDDEs) -- microcrystalline (B-MCDE) and ultrananocrystalline (B-UNCDE) were applied for the electrochemical reduction of several selected purine nucleotides -- Guanosine 5'-monophosphate (GMP), 2'-Deoxyguanosine 5'-monophosphate (dGMP), Adenosine 5'-monophosphate (AMP), Adenosine 5'-diphosphate ...
arxiv +1 more source