Results 151 to 160 of about 347,631 (311)

Lysine acetyltransferase 2A-mediated succinylation of adenosine monophosphate-activated protein kinase suppresses gallstone formation by inhibiting inflammation and pyroptosis. [PDF]

World J Gastroenterol
Wang XX, Ma MZ, Zhu LC, Dai LF, Qin C, Shao S, Xu XW, Gao RX, Zhang ZH.   +8 more
europepmc   +1 more source

Competitive Inhibition of Adrenal Δ5-3β-Hydroxysteroid Dehydrogenase and Δ5-3-Ketosteroid Isomerase Activities by Adenosine 3',5'-Monophosphate

, 1970
Ronald W. McCune, Sidney Roberts, Peggy L. Young   +2 more
openalex   +1 more source

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

Small Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto, Nine R. Kok, Philipp C. Hauger, Manon Karsten‐van Diepen, Michael de Kok, Nanne J. Paauw, Susanne M. A. van der Pol, Joline P. Nugteren‐Boogaard, Peter L. Hordijk, Stephanie D. Beekhuis‐Hoekstra, Susan Gibbs, Nienke M. de Wit, Helga E. de Vries   +12 more
wiley   +1 more source

MetaAMPK: Accurate Prediction of Adenosine Monophosphate-Activated Protein Kinase Activators Using a Meta-Learner Neural Network. [PDF]

ACS Omega
Intan AEK, Zetta DN, Jarukamjorn K, Srisongkram T.   +3 more
europepmc   +1 more source

Cyclic adenosine monophosphate potentiates immune checkpoint blockade therapy in acute myeloid leukemia. [PDF]

Clin Transl Med, 2023
Mao P, Feng W, Zhang Z, Huang C, Zhou S, Zhao Z, Mu Y, Zhao AY, Wang L, Li F, Zhao AZ.   +10 more
europepmc   +1 more source

Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes.

Brain : a journal of neurology, 2012
Subir K. Roy Chowdhury, Darrell R. Smith, A. Saleh, J. Schapansky, A. Marquez, S. Gomes, Eli Akude, Dwane Morrow, N. Calcutt, P. Fernyhough   +9 more
semanticscholar   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Structural Heterogeneity of Proteoform-Ligand Complexes in Adenosine Monophosphate-Activated Protein Kinase Uncovered by Integrated Top-Down Mass Spectrometry. [PDF]

J Am Chem Soc
Chan HJ, Krichel B, Bandura LJ, Chapman EA, Rogers HT, Fischer MS, Roberts DS, Gao Z, Wang MD, Wu J, Uetrecht C, Jin S, Ge Y.   +12 more
europepmc   +1 more source

miRNA Profiling of Cholesteatoma‐Derived Exosomes Reveals Exosomal miR‐223‐3p and miR‐142‐5p as Potential Biomarkers for Acquired Middle Ear Cholesteatoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Acquired cholesteatoma is an abnormal and invasive growth of keratinized squamous epithelial cells in the middle ear. The study aims to explore the role of exosomal miRNAs in the pathogenesis of acquired cholesteatoma and their potential in clinical application.
Qi Tang, Meng‐Yao Xie, Shu Wang, Zhi‐Yuan Wu, Zhi‐Jin Han, Chen Li, Shu‐Yi Wang, Yuan Cao, Yu‐Run Chen, Bin Wang, Ying‐Ying Shang, Xiao‐Wu Huang, Hua Yang   +12 more
wiley   +1 more source

TrkA of <i>Streptococcus mitis</i> CCUG31611 binds cyclic di-adenosine monophosphate and is required for growth in low potassium conditions. [PDF]

Microbiology (Reading)
Vevik K, Sribasgaran B, Cai K, Naemi AO, Pedersen Kaspersen H, Uhlig S, Økstad OA, Simm R.   +7 more
europepmc   +1 more source