Results 201 to 210 of about 227,189 (359)

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh   +4 more
wiley   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara   +3 more
wiley   +1 more source

Effects of Genistein on Inflammasome Induced Pancreatic β‐Cell Apoptosis by Dexamethasone

open access: yesMolecular Nutrition &Food Research, EarlyView.
The possible mechanism of genistein‐mediated protection against dexamethasone‐induced pancreatic β‐cell apoptosis. Genistein decreases the activation of IRE‐1α, resulting in the reduction of sXBP1, JNK, TXNIP, NLRP3, and IL‐1β expression. Genistein inhibits dexamethasone‐induced pancreatic β‐cell apoptosis.
Nattinee Jitprawet   +4 more
wiley   +1 more source

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