Results 211 to 220 of about 95,796 (312)
A series of modified FAD cofactors have been used to modulate the photochemistry of FAD‐containing cryptochrome. When 7‐halogenated FADs were used, a significantly faster signaling‐state formation was observed, due to the more positive reduction potentials and higher triplet yields compared to the natural FAD cofactors; thus, this study shows that the ...
Moustafa Okasha+8 more
wiley +1 more source
The activation of adenosine monophosphate-activated protein kinase inhibits the migration of tongue squamous cell carcinoma cells by targeting Claudin-1 via epithelial-mesenchymal transition. [PDF]
Zhou XY+9 more
europepmc +1 more source
The adenylyl cyclase (AC) Rv1625c from M. tuberculosis is a monomeric progenitor of the nine pseudoheterodimeric mammalian AC isoforms. The hexahelical membrane anchor of Rv1625c serves as an inhibitory receptor for fatty acids, particularly oleic acid. One ligand binds into each monomer of the active Rv1625c dimer.
Anita Charlotte Friderun Schultz+3 more
wiley +1 more source
The Effect of Bacterial AHL on the Cyclic Adenosine Monophosphate Content in Plants According to High-Performance Liquid Chromatography. [PDF]
Zhao X+5 more
europepmc +1 more source
Protein kinase A: a quirky prototype
Protein kinase A (PKA) has served as a prototype for establishing kinase fundamentals, including sequence, structure and catalytic mechanism. However, PKA is quirky in some respects. Its regulatory elements are expressed separately, including type I (RI) regulatory subunits that contain unusual disulphide‐linked dimerization and docking domains ...
Matthew G. Gold
wiley +1 more source
Severe Hypertrophic Cardiomyopathy Caused by a Protein Kinase Adenosine Monophosphate-Activated Non-catalytic Subunit Gamma 2 (PRKAG2) Mutation With Refractory Chylous Effusions in a Neonate: A Case Report and Literature Review. [PDF]
Minamitani Y+5 more
europepmc +1 more source
Ras pathways help buffer biological timekeeping against metabolic perturbations
Circadian clocks must be buffered (compensated) against conditions that could affect their rate (period). This figure shows rhythmic peaks of spore formation driven by the clock of the fungus Neurospora: The period is the same under different nutritional conditions in the wild‐type but not in a RasGEF mutant that disrupts an intracellular signaling ...
Patricia Lakin‐Thomas
wiley +1 more source