Results 241 to 250 of about 293,395 (315)

Viability Profiles of Normal and Cancer Bladder Cells With Metformin, Nitrate and Adenosine Monophosphate-Activated Protein Kinase Inhibitor. [PDF]

World J Oncol
Abdelmoaty H, Good S, Phan T.
europepmc   +1 more source

Efficacy and safety of CT‐868, a novel, fully biased, dual glucagon‐like peptide‐1/glucose‐dependent insulinotropic polypeptide receptor agonist, in type 2 diabetes: A double‐blind, randomized placebo controlled phase 2 trial

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To assess the glycaemic efficacy and safety of CT‐868, a cAMP signal‐biased, dual glucagon‐like peptide‐1/glucose‐dependent insulinotropic polypeptide receptor agonist, in participants with type 2 diabetes (T2D). Materials and Methods This 26‐week (W), phase 2, randomized, double‐blind placebo‐controlled trial enrolled adults with T2D ...
Manu V. Chakravarthy, Michael A. Elliott, Luis Acosta, Gabriele E. Sonnenberg, Damian Bialonczyk, Jingtao Wu, Federico A. Argüelles‐Tello, Raymundo Garcia‐Reza, José Gerardo González‐González, Stig K. Hansen, Juan P. Frias   +10 more
wiley   +1 more source

LncRNAs are involved in regulating ageing and age-related disease through the adenosine monophosphate-activated protein kinase signalling pathway. [PDF]

Genes Dis
Li J, Xiao F, Wang S, Fan X, He Z, Yan T, Zhang J, Yang M, Yang D.   +8 more
europepmc   +1 more source

Cyclic Adenosine Monophosphate: Function in Photoreceptors [PDF]

Science, 1971
Inactivation of adenylate cyclase in outer segments of retinal photoreceptor cells is proportional to the bleaching of rhodopsin. Membranes of the outer segments also contain a particulate, light-insensitive phosphodiesterase of high specific activity. In electrophysiological experiments, application of cyclic adenosine monophosphate along
William H. Miller, Mark W. Bitensky, Ronnie E. Gorman   +2 more
openaire   +2 more sources

A chronocoulometric aptamer sensor for adenosine monophosphate [PDF]

Chemical Communications, 2007
The selective recognition of adenosine monophosphate by a half-duplex aptamer-modified electrode leads to a simple chronocoulometric aptasensor based on the changes in surface charges.
Shali He, Yihan Li, Li Shen, Pingli He, Yuanhua Shao, Shubao Xie, Ping Jing, Zhong Chen   +7 more
openaire   +2 more sources

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Effects of adenosine 5′-monophosphate and adenosine 3′,5′-cyclic monophosphate on l cells

Journal of Cell Science, 1975
ABSTRACT The adenine nucleotides, 5′-AMP and 3′5′-cyclic AMP block L cells in the S-phase of the cell cycle. The intracellular level of cyclic AMP is reduced after incubation of cells with 5′-AMP, and rates of uridine transport are increased after incubation with either 5′-AMP or cyclic AMP.
A. Eukarpidou, J. Taylor-Papadimitriou, G. Karamanlidou, T. Karemfyllis   +3 more
openaire   +3 more sources

Adenosine diphosphate and adenosine monophosphate: enzymatic spectrophotometric determination

The Journal of Nutritional Biochemistry, 1990
Determination enzymatique et spectrophotometrique de l'adenosine diphosphate (ADP) et de l'adenosine monophosphate (AMP). Phosphorylation de l'ADP par une pyruvate kinase puis reduction du pyruvate en presence de NADH. Mesure de la consommation de NADH au spectrophotometre a 340 nm.
Vera Schultz, Keith Tornheim
openaire   +3 more sources

Origin of Cyclic Adenosine Monophosphate in Saliva

Journal of Dental Research, 1975
The level of cyclic adenosine monophosphate (AMP) in duct saliva from the dog submandibular gland was increased after cyclic AMP was administered intravenously in vivo. Isoproterenol increased the level of cyclic AMP in plasma and saliva in vivo and in salivary gland slices in vitro, but increased the level only slightly in saliva in a perfused dog ...
Takao Kanamori, Shosei Matsumoto, Toshiharu Nagatsu   +2 more
openaire   +2 more sources

Stimulation of erythropoiesis by cyclic adenosine monophosphate

Life Sciences, 1971
Abstract CYCLIC AMP stimulated the incorporation of radioiron by the red blood cells in polycythemic mice. This effect was potentiated by prior incubation of cyclic AMP with dialyzed rat serum and was partially abolished in vivo , but not in vitro , by anti-erythropoietin.
Anthony S. Gidari, Esmail D. Zanjani, Albert S. Gordon   +2 more
openaire   +3 more sources