Results 241 to 250 of about 95,796 (312)

Purification of and Properties of the Cyclic Adenosine 3',5'-Monophosphate Receptor Protein which Mediates Cyclic Adenosine 3',5'-Monophosphate-dependent Gene Transcription in Escherichia coli

, 1971
Wayne B. Anderson, Arthur B. Schneider, Michael Emmer, Robert L. Perlman, Ira Pastan   +4 more
openalex   +1 more source

Staphylococcus aureus COL: An Atypical Model Strain of MRSA That Exhibits Slow Growth and Antibiotic Tolerance due to a Mutation in PRPP Synthetase

Molecular Microbiology, EarlyView.
COL is an unusual “model” strain of Staphylococcus aureus that exhibits slow growth and multidrug antibiotic tolerance. This phenotype is primarily due to a mutation in Prs, which synthesizes the core metabolite phosphoribosyl pyrophosphate (PRPP). Introduction of the COL Prs allele into the antibiotic‐susceptible strain Newman confers tolerance, while
Claire E. Stevens, Ashley T. Deventer, Paul R. Johnston, Phillip T. Lowe, Alisdair B. Boraston, Joanne K. Hobbs   +5 more
wiley   +1 more source

Investigating the Relevance of Cyclic Adenosine Monophosphate Response Element-Binding Protein to the Wound Healing Process: An In Vivo Study Using Photobiomodulation Treatment. [PDF]

Int J Mol Sci
Kim S, Park J, Choi Y, Jeon H, Lim N.
europepmc   +1 more source

TIR innovations in plant immunity

New Phytologist, EarlyView.
Summary Toll/interleukin‐1 receptor (TIR) domain‐containing immune receptors are crucial for plant immunity, with recent advancements highlighting the enzymatic functions of TIR domains and their production of signaling molecules. TIR‐catalyzed compounds interact with receptors to form functional modules that trigger the oligomerization of helper ...
Zhongshou Wu
wiley   +1 more source

Old Doubts From a New Perspective: Oral Versus Subcutaneous Methotrexate

International Journal of Dermatology, EarlyView.
Laura Kiss, Rolland Gyulai
wiley   +1 more source

Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso, Alejandro Schcolnik‐Cabrera, Mengyi Zhu, Erin Strachan, Xavier Clemente‐Casares, Sue Tsai   +5 more
wiley   +1 more source

Lactucopicrin promotes fatty acid β-oxidation and attenuates lipid accumulation through adenosine monophosphate-activated protein kinase activation in free fatty acid-induced human hepatoblastoma cancer cells. [PDF]

Food Sci Nutr
Tan H, Mi N, Tong F, Zhang R, Abudurexiti A, Lei Y, Zhong Y, Yan J, Yang J, Ma X.   +9 more
europepmc   +1 more source

Mandibular Condylar Cartilage in Development and Diseases: A PTHrP‐Centric View

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT The mandibular condylar cartilage (MCC) is a dual‐function component of the temporomandibular joint (TMJ), acting as both articular cartilage for jaw movement and growth cartilage for vertical growth of the mandibular condyle. Parathyroid hormone‐related protein (PTHrP) plays a critical role in orchestrating chondrogenesis in the long bone ...
Chiaki Tsutsumi‐Arai, Amy Tran, Yuki Arai, Wanida Ono, Noriaki Ono   +4 more
wiley   +1 more source

Plant‐derived vesicle‐like nanoparticles in food crops: emerging insights into nutritional biofortification and biomedical applications

Plant Biotechnology Journal, EarlyView.
Summary Food crops, as the cornerstone of human nutrition, not only provide essential macronutrients but also encompass a rich spectrum of bioactive compounds that promote health. Of particular significance are underutilized minor crops, which contain unique beneficial components with proven nutraceutical properties. These valuable bioactive components
Jie Wang, Zhaosheng Kong
wiley   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source