Results 81 to 90 of about 165,902 (383)

UV resistance of nucleosides -- an experimental approach [PDF]

, 2020
The emergence of life on Earth is a highly discussed but still unsolved question. Current research underlines the importance of environments within close proximity to the Earth's surface as they can solve long-standing problems such as polymerization of nucleotides and phosphorylation of nucleosides.
arxiv   +1 more source

Adenosine monophosphate degradation and inosinic acid accumulation in the shrimp Penaeus japonicus

International Aquatic Research, 2017
Shrimp muscle contains taste component compounds, such as glutamic acid and inosinic acid (IMP). When both are present, taste intensity increases by fourfold to eightfold compared to that when only glutamic acid is present. Inosinic acid is generated via
Hiroko Seki, Kaori Nakazato, Naoko Hamada-Sato   +2 more
doaj   +1 more source

Homocysteine Promotes the Pathogenesis of Atherosclerosis through the Circ‐PIAS1‐5/miR‐219a‐2‐3p/TEAD1 Axis

Advanced Science, EarlyView.
A model is schematically represented for the major molecular mechanisms by which homocysteine (Hcy) accelerates the nuclear export of circ‐PIAS1‐5, which regulates atherosclerosis by acting as a competing endogenous RNA for miR‐219a‐2‐3p. Hcy enrichment of circ‐PIAS1‐5 leads to YTHDC1 binding to circ‐PIAS1‐5 and promotes its intracellular localization ...
Shengchao Ma, Fei Ma, Ning Ding, Lin Xie, Anning Yang, Jiangyong Shen, Yun jiao, Kai Wu, YueE Chai, Zhigang Bai, Jiantuan Xiong, Nan Li, Huiping Zhang, Yideng Jiang   +13 more
wiley   +1 more source

The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson’s disease

Neural Regeneration Research
Interferon regulatory factor 7 plays a crucial role in the innate immune response. However, whether interferon regulatory factor 7-mediated signaling contributes to Parkinson’s disease remains unknown.
Shengyang Zhou, Ting Li, Wei Zhang, Jian Wu, Hui Hong, Wei Quan, Xinyu Qiao, Chun Cui, Chenmeng Qiao, Weijiang Zhao, Yanqin Shen   +10 more
doaj   +1 more source

Hypoxanthine-guanine phosphoribosyltransferase and inosine 5’-monophosphate dehydrogenase activities in three mammalian species: aquatic (Mirounga angustirostris), semiaquatic (Lontra longicaudis annectens) and terrestrial (Sus scrofa)

Frontiers in Physiology, 2015
Aquatic and semiaquatic mammals have the capacity of breath hold (apnea) diving. Northern elephant seals (Mirounga angustirostris) have the ability to perform deep and long duration dives; during a routine dive, adults can hold their breath for 25 min ...
Myrna eBarjau Perez-Milicua, Tania eZenteno-Savin, Daniel E. Crocker, Juan Pablo Gallo   +3 more
doaj   +1 more source

Untargeted metabolomics of saliva in pregnant women with and without gestational diabetes mellitus and healthy non-pregnant women

Frontiers in Cellular and Infection Microbiology, 2023
ObjectiveThe aim of this study was to compare the differences in salivary metabolites between pregnant women with gestational diabetes mellitus (GDM), healthy pregnant women (HPW), and healthy non-pregnant women (HNPW), and analyze the possible ...
Yueheng Li, Yueheng Li, Yueheng Li, Yueheng Li, Yang Feng, Zhengyan Yang, Zhengyan Yang, Zhengyan Yang, Zhengyan Yang, Zhi Zhou, Zhi Zhou, Zhi Zhou, Zhi Zhou, Dan Jiang, Dan Jiang, Dan Jiang, Dan Jiang, Jun Luo, Jun Luo, Jun Luo, Jun Luo   +20 more
doaj   +1 more source

Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy

Advanced Science, EarlyView.
Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu, Yuxiao Feng, Mathilde Lepoitevin, Meng Yu, Christian Serre, Jun Ge, Yuan Huang   +6 more
wiley   +1 more source

ENPP1 deficiency: A clinical update on the relevance of individual variants using a locus‐specific patient database

Human Mutation, Volume 43, Issue 12, Page 1673-1705, December 2022., 2022
Abstract Loss‐of‐function variants in the ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) cause ENPP1 Deficiency, a rare disorder characterized by pathological calcification, neointimal proliferation, and impaired bone mineralization. The consequence of ENPP1 Deficiency is a broad range of age dependent symptoms and morbidities
Stephanie A. Mercurio, Lauren M. Chunn, Gus Khursigara, Catherine Nester, Kathleen Wray, Ulrike Botschen, Mark J. Kiel, Frank Rutsch, Carlos R. Ferreira   +8 more
wiley   +1 more source

Thesis: The Effects of Hypoxia, Metabolic Restriction and Magnetic Fields on Chromosome Instability and Karyotype Contraction in Cancer Cell Lines [PDF]

arXiv, 2014
Background: Biological effects of extra-low-frequency (ELF) magnetic fields (MFs) have lacked a credible mechanism of interaction between MFs and living material. Objectives: To examine the effect of ELF-MFs on cancer cells. Methods: Five cancer cell lines were exposed to ELF-MFs within the range of 0.025-5 microTesla, and the cells were examined for ...
arxiv  

Synthesis of tuneable gold nanostars: the role of adenosine monophosphate

Journal of Materials Chemistry C, 2023
Gold nanostars with tuneable optical properties are synthesizedviaa seed-mediated approach employing adenosine monophosphate (AMP) as a capping ligand. AMP directs the reduction of the gold salt and mediates the anisotropic nanoparticle growth.
Carlos Fernández-Lodeiro, Javier Fernández-Lodeiro, Adrián Fernández-Lodeiro, Silvia Nuti, Carlos Lodeiro, Alec LaGrow, Ignacio Pérez-Juste, Jorge Pérez-Juste, Isabel Pastoriza-Santos   +8 more
openaire   +2 more sources