Results 161 to 170 of about 2,608,509 (268)

Antimetastatic effects of blocking PD-1 and the adenosine A2A receptor.

Cancer Research, 2014
D. Mittal, A. Young, Kimberley A Stannard, M. Yong, M. Teng, B. Allard, J. Stagg, M. Smyth   +7 more
semanticscholar   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

A_2B adenosine receptor signaling and regulation. [PDF]

Purinergic Signal
Gao ZG, Haddad M, Jacobson KA.
europepmc   +1 more source

Overactivity of neuronal adenosine A2A receptors accelerates neurodegeneration [PDF]

, 2019
Rodrigo A. Cunha
openalex   +1 more source

DCAF12 Ubiquitin Ligase Promotes Lung Cancer Metastasis by Modulating the TRiC/CCT Chaperonin Complex

Advanced Science, EarlyView.
This study elucidates how DCAF12 facilitates non‐degradative ubiquitination to stabilize TRiC/CCT, thereby enhancing the folding capacity of chaperonins. This mechanism promotes the maturation of cytoskeletal proteins and activates key oncogenic drivers, including YAP, STAT3, and mTOR, ultimately driving metastatic progression in lung cancer.
Zhenyi Wang, Huanhuan Huang, Kaizong Huang, Xiaowen Cui, Leilei Wu, Renyu Lin, Zhe Zhao, Hua Chen, Cheng Zheng, Weilin Jin, Song Chen, Jiayan Chen, Yaping Xu, Dongping Wei   +13 more
wiley   +1 more source

Unlocking the adenosine receptor mechanism of the tumour immune microenvironment. [PDF]

Front Immunol
Han Y, Dong C, Hu M, Wang X, Wang G.
europepmc   +1 more source

Assay-Dependent Inverse Agonism at the A₃ Adenosine Receptor: When Neutral Is Not Neutral. [PDF]

ACS Pharmacol Transl Sci, 2023
Pottie E, Suresh RR, Jacobson KA, Stove CP.   +3 more
europepmc   +1 more source

Corrections to “Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells” [PDF]

, 2007
Masato Iino, Ritsuko Ehama, Yosuke Nakazawa, Tokuro Iwabuchi, Masashi Ogo, Masahiro Tajima, Seiji Arase   +6 more
openalex   +1 more source

Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells

Advanced Science, EarlyView.
Brief 10 min bursts of high frequency (10 MHz) vibrational mechanostimulation to stem cells are shown to activate their epigenetic machinery to condition their differentiation down an osteogenic lineage within just 3 days, which is much earlier than that with other forms of mechanostimuli, and without requiring any biochemical additives. Abstract Cells
Lizebona A. Ambattu, Blanca del Rosal, Carmelo Ferrai, Leslie Y. Yeo   +3 more
wiley   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source