Results 251 to 260 of about 2,801,899 (401)

Adenosine Receptor Antagonists Including Caffeine Alter Fetal Brain Development in Mice

Science Translational Medicine, 2013
Carla G. Silva, C. Métin, W. Fazeli, Nuno J. Machado, S. Darmopil, P. Launay, A. Ghestem, M. Nesa, Emilie Bassot, E. Szabó, Younis Baqi, C. Müller, Â. R. Tomé, A. Ivanov, D. Isbrandt, Y. Zilberter, R. Cunha, M. Esclapez, C. Bernard   +18 more
semanticscholar   +1 more source

Spatiotemporally Controlled Tumor Photodynamic/Immunotherapy Therapy Based on Upconversion Hybrid Nanosystem

Advanced Science, EarlyView.
PURH is constructed by a five‐layer upconversion nanoparticle (UCNP) surface coated with mesoporous silica, which encapsulates rose bengal (RB) within the mesoporous channels. Additionally, CpG oligonucleotides (CpG ODN) is linked to the surface, followed by the surface functionalization of hyaluronic acid (HA). This spatiotemporally controllable smart
Fang Wang, Wenfei Xu, Yuechen Liu, Shuxuan Zhu, Wenjing Liu, Shuhui Bo, Hong Sun, Bei Liu, Zhaogang Sun, Hongqian Chu   +9 more
wiley   +1 more source

Bile acids inhibit equilibrative adenosine transport to alter adenosine receptor signaling in cholestasis. [PDF]

J Biol Chem
Joshi A, Chen S, Rahman FM, Nair S, Cheng X, Govindarajan R.   +5 more
europepmc   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

Anticancer Activity of Triterpene Glycosides Cucumarioside A₀-1 and Djakonovioside A Against MDA-MB-231 as A_2B Adenosine Receptor Antagonists. [PDF]

Int J Mol Sci
Zelepuga EA, Chingizova EA, Menchinskaya ES, Pislyagin EA, Avilov SA, Kalinin VI, Aminin DL, Silchenko AS.   +7 more
europepmc   +1 more source

Acute saline expansion increases nephron filtration and distal flow rate but maintains tubuloglomerular feedback responsiveness: role of adenosine A₁receptors

, 2012
Roland C. Blantz, Prabhleen Singh, Aihua Deng, Scott C. Thomson, Volker Vallon   +4 more
openalex   +2 more sources

Inhibition of PAF-induced aggregation of human PMNs and platelets by adenosine: in vitro investigations using a newly developed blood filtration system [PDF]

, 1992
Arbogast, Helmut, Dammer, U., Dendorfer, A., Meier-Ewert, H., Nees, S., Schönharting, M., Stiegler, H., Strohmenger, R.   +7 more
core   +1 more source

DNMT2‐m5C‐ACLY Axis Promotes Lenvatinib Resistance in Hepatocellular Carcinoma Through Histone Acetylation‐Mediated Notch Pathway

Advanced Science, EarlyView.
Lenvatinib resistance poses a major challenge in advanced hepatocellular carcinoma (HCC). This study reveals that DNMT2 upregulation is a key driver, which stabilizes ACLY mRNA via m5C modification and activates the Notch signaling pathway. Crucially, combining ACLY inhibitors with lenvatinib overcomes resistance and suppresses tumors, offering a ...
Shiguang Yang, Jie Li, Shengwei Mao, Xuhui Zhao, Douwaner Liu, Jiafeng Chen, Jialu Fu, Yichao Bu, Xiaoling Wu, Shaoqing Liu, Qifeng Yu, Qiongzhu Dong, Zheng Tang, Yuan Fang, Yinghong Shi   +14 more
wiley   +1 more source

A_2A Adenosine Receptor Antagonists and Their Efficacy in Rat Models of Parkinson's Disease. [PDF]

Cells
Spinaci A, Buccioni M, Dal Ben D, Francucci B, Klotz KN, Marucci G, Simola N, Morelli M, Pinna A, Volpini R, Lambertucci C.   +10 more
europepmc   +1 more source

Caffeine for Prevention of Alzheimer's Disease: Is the A_2A Adenosine Receptor Its Target? [PDF]

Biomolecules, 2023
Merighi S, Travagli A, Nigro M, Pasquini S, Cappello M, Contri C, Varani K, Vincenzi F, Borea PA, Gessi S.   +9 more
europepmc   +1 more source