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Adenosine Receptors in Health and Disease
2011The adenosine receptors A(1), A(2A), A(2B), and A(3) are important and ubiquitous mediators of cellular signaling, which play vital roles in protecting tissues and organs from damage. In particular, adenosine triggers tissue protection and repair by different receptor-mediated mechanisms, including an increase of oxygen supply/demand ratio ...
GESSI, Stefania +3 more
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Adenosine Receptors on Human Lymphocytes
1986Evidence is accumulating that adenosine functions as an important immunoregulatory autacoid (1,2). Adenosine inhibits the mitotic response of human lymphocytes (3,4), lymphocyte-mediated cytolysis (5), superoxide anion generation by neutrophils (6), platelet aggregation (7) and mediator release from human basophils (8-10). The nucleoside has been shown
MARONE, GIANNI +3 more
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Adenosine, adenosine receptors and glaucoma: An updated overview
Biochimica et Biophysica Acta (BBA) - General Subjects, 2013Glaucoma, a leading cause of blindness worldwide, is an optic neuropathy commonly associated with elevated intraocular pressure (IOP). The major goals of glaucoma treatments are to lower IOP and protect retinal ganglion cells. It has been revealed recently that adenosine and adenosine receptors (ARs) have important roles in IOP modulation and ...
Yisheng, Zhong +3 more
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[Adenosine and adenosine receptors in the kidney].
Nihon rinsho. Japanese journal of clinical medicine, 1993In the kidney, adenosine plays important regulatory roles, including renal blood flow, glomerular filtration rate, renin secretion, tubuloglomerular feedback, tubular reabsorption of sodium and water, sympathetic neurotransmitter release, and erythropoietin secretion.
S, Umemura +6 more
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Lymphocytes and adenosine receptors
Pharmacological Research, 1992DIANZANI, Chiara +3 more
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