Results 271 to 280 of about 350,006 (309)

The cumulative analgesic effect of repeated electroacupuncture is modulated by Adora3 in the SCDH of mice with neuropathic pain

Animal Models and Experimental Medicine, EarlyView.
Neuropathic pain management via repeated electroacupuncture. Abstract Background Existing remedial approaches for relieving neuropathic pain (NPP) are challenging and open the way for alternative therapeutic measures such as electroacupuncture (EA). The mechanism underlying the antinociceptive effects of repeated EA sessions, particularly concerning ...
Faisal Ayub Kiani, Hao Li, Panpan Guo, Qiulin Zhang, Mahmoud M. Abouelfetouh, Mingxing Ding, Yi Ding   +6 more
wiley   +1 more source

Cantharidin and sodium fluoride attenuate the negative inotropic effect of the A₁-adenosine receptor agonist N⁶-(R)-phenylisopropyl adenosine in isolated human atria. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Schwarz R, Hofmann B, Gergs U, Neumann J.   +3 more
europepmc   +1 more source

Metabolic alterations in human pulmonary artery smooth muscle cells treated with PDGF‐BB

Animal Models and Experimental Medicine, EarlyView.
Metabolic abnormalities are considered to play a key regulatory role in vascular remodeling of pulmonary arterial hypertension. We analyzed the metabolome in the culture supernatants of human pulmonary artery smooth muscle cells (PASMC) during the malignant proliferation phenotype transition via a targeted metabolomics method. Significant and extensive
Meng‐Jie Zhang, Jie‐Jian Kou, Hong‐Da Zhang, Xin‐Mei Xie, Yun‐Feng Zhou, Ping Yuan, Xiao‐Bin Pang, Lu‐Ling Zhao, Jing Qiu, Yang‐Yang He   +9 more
wiley   +1 more source

Multiple Controls by Adenosine Receptors on the Adenylate Cyclase in the Rat Hepatic Membrane

, 1990
Sumio Shima, Nobu AKAMATU
openalex   +1 more source

Multiple low dose streptozotocin‐induced diabetes as a model for studying autoimmune diabetes in humans

Animal Models and Experimental Medicine, EarlyView.
Multiple low dose streptozotocin‐induced diabetes is a valuable animal model of diabetes type 1. It should be improved by further research on autoantigens, microbiota and mucosal immune cells from the gut, but also from other organs. Abstract The autoimmune response directed against pancreatic β cells is the most essential pathogenic process in type 1 ...
Ivan Koprivica, Suzana Stanisavljević, Dragica Mićanović, Ivana Stojanović, Đorđe Miljković   +4 more
wiley   +1 more source

Chirality Makes or Breaks Chemically Driven Self‐Assembly

Angewandte Chemie, EarlyView.
Chirality‐controlled reaction cycles: Reaction cycles are constructed to respond to the chirality (handedness) of an acylating agent. Left‐ and right‐handed aminoacyl phosphate esters modulate the structure, lifetime, and transformation of transient (thio)ester intermediates, enabling control over distinct chemical pathways using molecules that are ...
Lenard Saile, Kun Dai, Mahesh D. Pol, Thejus Pramod, Ralf Thomann, Charalampos G. Pappas   +5 more
wiley   +2 more sources

Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy

Annals of Neurology, EarlyView.
Objective To assess the diagnostic accuracy of metabolites in cerebrospinal fluid (CSF) for central nervous system (CNS) infections. Methods Patients were derived from three prospective cohort studies in the Netherlands. All studies included adults suspected of a CNS infection who underwent a diagnostic lumbar puncture.
Steven L. Staal, Sabine E. Olie, Michel van Weeghel, Bauke V. Schomakers, Frédéric M. Vaz, I‐PACE Study Group, Diederik van de Beek, Matthijs C. Brouwer   +7 more
wiley   +1 more source

Flexibility‐Aided Orientational Self‐Sorting and Transformations of Bioactive Homochiral Cuboctahedron Pd12L16

Angewandte Chemie, EarlyView.
Mimicking concave morphologies found in nature, we have introduced flexible, unsymmetric, tridentate ligand (L) which undergoes coordination self‐assembly into highly organized chiral Pd6L8 or Pd12L16 cages that can undergo interspecific transformations. The cages, being based on natural amphiphilic transport molecules, mediate high cellular uptake and
Subhasis Chattopadhyay, Robin Durník, Anniina Kiesilä, Elina Kalenius, Juha M. Linnanto, Pavel Babica, Jan Kuta, Radek Marek, Ondřej Jurček   +8 more
wiley   +2 more sources

Emerging Strategies for Platelet‐Modified Nanoparticles in Targeted Tumor Therapy

Advanced NanoBiomed Research, EarlyView.
This review highlights innovative strategies using platelet‐modified nanoparticles to target tumors more precisely. By mimicking platelet functions, these biomimetic carriers improve tumor homing, enhance drug delivery, and reduce immune clearance.
Chunyu Bai, Lan Sun, Yimin Cui, Huan Meng, Jiulong Li, Qian Xiang   +5 more
wiley   +1 more source