Results 271 to 280 of about 2,712,589 (407)

Adenosine analogues with specificity for A2 receptors bind to mouse spermatozoa and stimulate adenylate cyclase activity in uncapacitated suspensions [PDF]

, 1993
L. R. Fraser, A. E. Duncan
openalex   +1 more source

Adenosine Receptor Antagonists Including Caffeine Alter Fetal Brain Development in Mice

Science Translational Medicine, 2013
Carla G. Silva, C. Métin, W. Fazeli, Nuno J. Machado, S. Darmopil, P. Launay, A. Ghestem, M. Nesa, Emilie Bassot, E. Szabó, Younis Baqi, C. Müller, Â. R. Tomé, A. Ivanov, D. Isbrandt, Y. Zilberter, R. Cunha, M. Esclapez, C. Bernard   +18 more
semanticscholar   +1 more source

The NLRP3 inflammasome pathway contributes to chronic inflammation in experimental autoimmune uveitis

Animal Models and Experimental Medicine, EarlyView.
The present study investigates the role of the NLRP3 inflammasome in the chronicity of ocular inflammation in uveitis using the experimental autoimmune uveitis (EAU) model. Whole eyes collected from EAU mice, 12 weeks post induction, were sectioned and subjected to immunohistochemistry. The confocal images from these sections were then assessed for the
Avik Shome, Ilva D. Rupenthal, Rachael L. Niederer, Odunayo O. Mugisho   +3 more
wiley   +1 more source

Cryo-EM structures of adenosine receptor A₃AR bound to selective agonists. [PDF]

Nat Commun
Cai H, Guo S, Xu Y, Sun J, Li J, Xia Z, Jiang Y, Xie X, Xu HE.   +8 more
europepmc   +1 more source

Sub-millisecond conformational dynamics of the A_2A adenosine receptor revealed by single-molecule FRET. [PDF]

Commun Biol, 2023
Maslov I, Volkov O, Khorn P, Orekhov P, Gusach A, Kuzmichev P, Gerasimov A, Luginina A, Coucke Q, Bogorodskiy A, Gordeliy V, Wanninger S, Barth A, Mishin A, Hofkens J, Cherezov V, Gensch T, Hendrix J, Borshchevskiy V.   +18 more
europepmc   +1 more source

Adenosine A₁‐receptor stimulated increases in intracellular calcium in the smooth muscle cell line, DDT₁MF‐2 [PDF]

, 1993
John M. Dickenson, Stephen J. Hill
openalex   +1 more source

Dopamine Transporter Imaging as Objective Monitoring Biomarker in Parkinson's Disease

Annals of Neurology, EarlyView.
Objective Although dopamine transporter (DaT) imaging is a valuable diagnostic biomarker, few studies have investigated its utility in objectively monitoring disease progression in patients with Parkinson's disease (PD). To date, no study has established a longitudinal relationship between the DaT signal decline and the motor symptom increase ...
Verena Dzialas, Gérard N. Bischof, Kathrin Möllenhoff, Alexander Drzezga, Thilo van Eimeren   +4 more
wiley   +1 more source

New Transferrin Receptor‐Targeting Conjugate Effectively Delivers DNA to Mouse Brain

Angewandte Chemie, EarlyView.
We present a novel RNA aptamer targeting the transferrin receptor (TfR), conjugated with DSPE lipid, which achieves remarkably efficient brain uptake, reaching brain‐to‐serum ratios as high as 6.5. Through fluorescence imaging and polymerase‐chain reaction analyses, we verify that this new conjugate successfully delivers a substantial amount of DNA ...
Min‐sun Song, Adrian H. Bustos, Lise Bastue, Justas Mikutavicius, Piotr Swiderski, Kelly J. Clemens, Nagy Habib, John Rossi, Kira Astakhova   +8 more
wiley   +2 more sources

Translational Experimental Basis of Indirect Adenosine Receptor Agonist Stimulation for Bone Regeneration: A Review. [PDF]

Int J Mol Sci
Ehlen QT, Mirsky NA, Slavin BV, Parra M, Nayak VV, Cronstein B, Witek L, Coelho PG.   +7 more
europepmc   +1 more source

Ivy Leaf Dry Extract EA 575^® Has an Inhibitory Effect on the Signalling Cascade of Adenosine Receptor A_2B. [PDF]

Int J Mol Sci, 2023
Meurer F, Häberlein H, Franken S.
europepmc   +1 more source