Results 291 to 300 of about 2,801,899 (401)

Therapeutic exploration potential of adenosine receptor antagonists through pharmacophore ligand-based modelling and pharmacokinetics studies against Parkinson disease. [PDF]

In Silico Pharmacol
Ajala A, Asipita OH, Michael AT, Tajudeen MT, Abdulganiyyu IA, Ramu R.   +5 more
europepmc   +1 more source

Synthesis and adenosine receptor affinity of a series of pyrazolo[3,4-d]pyrimidine analogs of 1-methylisoguanosine

, 1991
Fiona Harden, Ronald J. Quinn, Peter J. Scammells   +2 more
openalex   +1 more source

Predictions for cholesterol interaction sites on the A2A adenosine receptor.

Journal of the American Chemical Society, 2012
J. Lee, E. Lyman
semanticscholar   +1 more source

A Programmable Nanoreactor Orchestrates Cascade of DNA Sensing to Amplify cGAS‐STING Activation for Cancer Immunotherapy

Advanced Science, EarlyView.
A programmable nanoreactor was engineered for precise cGAS‐STING pathway activation in cancer immunotherapy. This strategy bridges targeted tumor DNA damage with DC immunomodulation, providing a translatable platform to unlock innate and adaptive antitumor immunity.
Shuang Liang, Yiwei Tian, Feiyu Zhao, Yue Han, Kongshuo Ma, Linna Hai, Kaiqing Yun, Yueyang Zhao, Siqi Zhang, Ziyi Zhang, Yuxuan Peng, Kuan Hu, Jing Zhong, Bai Xiang, Zhaohui Wang   +14 more
wiley   +1 more source

Cryo-EM structures of adenosine receptor A₃AR bound to selective agonists. [PDF]

Nat Commun
Cai H, Guo S, Xu Y, Sun J, Li J, Xia Z, Jiang Y, Xie X, Xu HE.   +8 more
europepmc   +1 more source

The Effect of A2A Adenosine Receptor Activation on C-C Chemokine Receptor 7 Expression in Human THP1 Macrophages During Inflammation

, 2011
Adrienne J. Williams, Bruce N. Cronstein
openalex   +1 more source

Universal Antibody‐Engineered Lipid Nanoparticles Potentiate Chemo‐Immunotherapy Against Triple‐Negative Breast Cancer by Reprogramming Tumor Cell Metabolism

Advanced Science, EarlyView.
A universal ROR1 antibody‐engineered lipid nanoparticle (LNP) is constructed by sequential drug encapsulation and antibody conjugation. The LNP not only enables enhanced chemotherapeutic efficiency by targeting drug delivery and precise localization of deep‐seated tumors through NIR‐II fluorescence imaging, but also remodels immunosuppressive TME ...
Yeneng Dai, Jiaqi Wang, Yu Liu, Guanda Jiao, Yuheng Gu, Yang Liu, Shengyu Fu, Xing Fan, Jialin Li, Ziang Guo, Kam Tong Leung, Lipeng Zhu, Qi Zhao   +12 more
wiley   +1 more source

Adenosine Receptor 3 in Liver Cancer: Expression Variability, Epigenetic Modulation, and Enhanced Histone Deacetylase Inhibitor Effects. [PDF]

Gastro Hep Adv
Kaldjob-Heinrich L, Nuciforo S, Lemke S, Stahl A, Czemmel S, Babaei S, Blukacz L, Meier MA, Zhang Y, Schürch CM, Gonzalez-Menendez I, Woelffing P, Malek NP, Scheble V, Nahnsen S, Claassen M, Templin M, Bösmüller H, Heim MH, Dauch D, Bitzer M.   +20 more
europepmc   +1 more source

Controlling murine and rat chronic pain through A3 adenosine receptor activation

The FASEB Journal, 2012
Zhoumou Chen, Kali Janes, Collin L. Chen, T. Doyle, Leesa Bryant, D. Tosh, K. Jacobson, D. Salvemini   +7 more
semanticscholar   +1 more source

Biomimetic Iridium‐Based Photothermal Nanozyme to Trigger Ferroptosis and Pyroptosis and Activate the cGAS‐STING Pathway for Improved Tumor Immunotherapy

Advanced Science, EarlyView.
This study develops an iridium‐based nanozyme (IIN@M) with superior enzyme‐like activity and photothermal performance. It disrupts intracellular redox balance by generating reactive oxygen species and depleting glutathione, which synergistically induces ferroptosis, pyroptosis, and immunogenic cell death.
Lijun Ding, Zhongxiong Fan, Guoyu Xia, Fukai Zhu, Nan Yang, Shujie Yu, Longlong Yuan, Jinyao Li   +7 more
wiley   +1 more source