Results 341 to 350 of about 2,801,899 (401)

Genetic and functional modulation by agonist MRS5698 and allosteric enhancer LUF6000 at the native A₃ adenosine receptor in HL-60 cells. [PDF]

Purinergic Signal
Gao ZG, Chen W, Gao RR, Li J, Tosh DK, Hanover JA, Jacobson KA.   +6 more
europepmc   +1 more source

Dietary Glutamine Supplementation Alleviated Rumen Epithelium Oxidative Damage and Apoptosis Induced by Feed Restriction via Maintaining Mitochondrial Homeostasis in Female Yaks

Animal Research and One Health, EarlyView.
Dietary glutamine (Gln) supplementation increased the ATP levels and promoted cell proliferation in the rumen epithelium of feed‐restricted yaks. Besides, Gln inhibited ROS accumulation and reduced oxidative damage and apoptosis in the rumen epithelium of feed‐restricted yaks.
Ziqi Yue, Shanpeng Ke, Liyuan Shi, Rui Hu, Zhisheng Wang, Quanhui Peng, Huawei Zou, Jianxin Xiao, Yahui Jiang, Fali Wu, Yiping Tang   +10 more
wiley   +1 more source

A_2B adenosine receptor-triggered intracellular calcium mobilization: Cell type-dependent involvement of G_i, G_q, G_s proteins and protein kinase C. [PDF]

Purinergic Signal
Gao ZG, Gao RR, Meyer CK, Jacobson KA.
europepmc   +1 more source

Antidepressant effects of selective adenosine receptor antagonists targeting the A1 and A2A receptors administered jointly with NMDA receptor ligands: behavioral, biochemical and molecular investigations in mice. [PDF]

Pharmacol Rep
Szopa A, Bogatko K, Serefko A, Herbet M, Ostrowska-Leśko M, Wróbel A, Radziwoń-Zaleska M, Dudka J, Wlaź P, Poleszak E.   +9 more
europepmc   +1 more source

Correction: A2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models. [PDF]

J Immunother Cancer
europepmc   +1 more source

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Adenosine Receptor Neurobiology: Overview

International review of neurobiology, 2014
Adenosine is a naturally occurring nucleoside that is distributed ubiquitously throughout the body as a metabolic intermediary. In the brain, adenosine functions as an important upstream neuromodulator of a broad spectrum of neurotransmitters, receptors, and signaling pathways.
Jiang-Fan, Chen, Chien-fei, Lee, Yijuang, Chern   +2 more
openaire   +3 more sources

Adenosine receptor subtypes

Trends in Pharmacological Sciences, 1993
The numerous and widespread effects of adenosine provide both an opportunity for the development of novel therapeutic agents acting via adenosine receptors and the challenge of achieving selectivity of action. The feasibility of achieving selectivity is enhanced if receptor subtypes can be identified.
M G, Collis, S M, Hourani
openaire   +2 more sources

Adenosine and Adenosine Receptors

American Journal of Respiratory Cell and Molecular Biology, 1990
In the last decade, there has been renewed interest in extracellular signaling by adenosine and adenine nucleotides. The potent cardiovascular effects of these agents were originally described by Drury and Szent-Gy6rgyi in 1929 (1). This report was followed by a flurry of interest in the use of adenosine as an antihypertensive agent, which subsided ...
openaire   +3 more sources

Adenosine receptors

2002
Abstract Adenosine is not a neurotransmitter but rather a paracrine neuromodulator. This obviously does not mean that adenosine is not biologically important—it just means that we must think differently about its role compared to, for example, dopamine or noradrenaline.
openaire   +2 more sources