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Adenosine and ATP Receptors in the Brain

Current Topics in Medicinal Chemistry, 2011
There is a widespread presence of both adenosine (P1) and P2 nucleotide receptors in the brain on both neurones and glial cells. Adenosine receptors play a major role in presynaptic neuromodulation, while P2X receptors are involved in fast synaptic transmission and synaptic plasticity. P2Y receptors largely mediate presynaptic activities.
Burnstock, Geoffrey +2 more
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Imaging of Adenosine Receptors

2014
Adenosine is a fundamental molecule of life and a main metabolite of the energy metabolism in humans and animals. The net effect of the neuromodulator adenosine on excitable tissue is inhibitory affecting the release of classical neurotransmitters. Adenosine and its receptors play an important role in the physiology and pathophysiology of the brain as ...
Marcus H. Holschbach +3 more
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Adenosine Receptors in Health and Disease

2011
The adenosine receptors A(1), A(2A), A(2B), and A(3) are important and ubiquitous mediators of cellular signaling, which play vital roles in protecting tissues and organs from damage. In particular, adenosine triggers tissue protection and repair by different receptor-mediated mechanisms, including an increase of oxygen supply/demand ratio ...
GESSI, Stefania +3 more
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Adenosine receptors

Neuropharmacology, 1995
T M, Palmer, G L, Stiles
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Lymphocytes and adenosine receptors