Compared with conventional liver transplantation, the expression of USP19 increases in ischemia‐free liver transplantation (IFLT) grafts. Overexpression of USP19 alleviates hepatocyte ferroptosis and graft ischemia‐reperfusion injury (IRI). USP19 protects SLC7A11 from autophagic degradation by removing K63‐linked ubiquitination, promoting ROS ...
Jinghong Xu+18 more
wiley +1 more source
Toxicity and stability of sodium cyanide in fresh water fish Nile tilapia
An experimental study was conducted to evaluate the effect of 0.129 NaCN mg/l for 28 days on the behavior of tilapia and the activities of adenosine triphosphatases enzyme (Na+/K+, Ca2+ and Mg2+-ATPase) within gill filaments, liver and muscles.
Enas M. Ramzy
doaj
Excited state dynamics in DNA double helices [PDF]
Recent ultrafast experiments have implicated that intrachain base-stacking rather than base-pairing mediate the fate and transport of photoexcited species in DNA chains. Here use an $SU(2)\otimes SU(2)$ lattice model which incorporates both intrachain and interchain electronic interactions to study the quantum mechanical evolution of an initial ...
arxiv
LEAD-ADENOSINE TRIPHOSPHATE COMPLEXES IN ADENOSINE TRIPHOSPHATASE HISTOCHEMISTRY [PDF]
Chelation of lead by adenosine triphosphate (ATP) and its consequences for adenosine triphosphatase histochemistry were examined. The formation constant of lead-ATP chelates was found by two methods to be 4.6-4.7 x 104. The characteristics of enzyme inhibition by lead were consistent with the predicted effects of lead-ATP chelation.
openaire +3 more sources
Protein Kinase C α Associates with Phospholipase D1 and Enhances Basal Phospholipase D Activity in a Protein Phosphorylation-Independent Manner in Human Melanoma Cells [PDF]
It is well known that phospholipase D plays a crucial part in the signal transduction of many types of cells, and is activated by protein kinase C α when cells are stimulated.
Goto, Akinobu+5 more
core +1 more source
Wnt signalosomes: What we know that we do not know
Wnt signaling occurs through a “signalosome” receptor complex, driven by oligomerization of the adaptor, Disheveled (Dvl). Both endocytosis and condensate formation have been proposed to mediate signalosome formation. Under pathological conditions, signalosomes may form in a Wnt ligand‐independent manner.
Heather Hartmann+6 more
wiley +1 more source
Large-Scale Discovery of ERK2 Substrates Identifies ERK-Mediated Transcriptional Regulation by ETV3 [PDF]
The mitogen-activated protein kinase (MAPK) extracellular signal–regulated kinase 2 (ERK2) is ubiquitously expressed in mammalian tissues and is involved in a wide range of biological processes.
Carlson, Scott M.+6 more
core +1 more source
The Mysterious World of Non‐Canonical Caps – What We Know and Why We Need New Sequencing Techniques
This review describes sophisticated methodologies such as LC–MS that enabled the identification of 5’ non‐canonical RNA caps and also surveys so far developed sequencing methods, evaluating their advantages and disadvantages. It emphasizes the need for developing new, reliable sequencing techniques to identify RNA types with non‐canonical caps enabling
Flaminia Mancini, Hana Cahova
wiley +1 more source
Frenkel Exciton Model of Ultrafast Excited State Dynamics in AT DNA Double Helices [PDF]
Recent ultrafast experiments have implicated intrachain base-stacking rather than base-pairing as the crucial factor in determining the fate and transport of photoexcited species in DNA chains. An important issue that has emerged concerns whether or not a Frenkel excitons is sufficient one needs charge-transfer states to fully account for the dynamics.
arxiv
Adenosine Triphosphatase and Myopathy [PDF]
Rhoda Blostein, G. A. Klassen
openaire +3 more sources