Results 91 to 100 of about 17,343 (255)

Suppression of Hepatocyte Ferroptosis via USP19‐Mediated Deubiquitination of SLC7A11 in Ischemia‐Free Liver Transplantation

open access: yesAdvanced Science, Volume 12, Issue 6, February 10, 2025.
Compared with conventional liver transplantation, the expression of USP19 increases in ischemia‐free liver transplantation (IFLT) grafts. Overexpression of USP19 alleviates hepatocyte ferroptosis and graft ischemia‐reperfusion injury (IRI). USP19 protects SLC7A11 from autophagic degradation by removing K63‐linked ubiquitination, promoting ROS ...
Jinghong Xu   +18 more
wiley   +1 more source

Toxicity and stability of sodium cyanide in fresh water fish Nile tilapia

open access: yesWater Science, 2014
An experimental study was conducted to evaluate the effect of 0.129 NaCN mg/l for 28 days on the behavior of tilapia and the activities of adenosine triphosphatases enzyme (Na+/K+, Ca2+ and Mg2+-ATPase) within gill filaments, liver and muscles.
Enas M. Ramzy
doaj  

Excited state dynamics in DNA double helices [PDF]

open access: yesarXiv, 2006
Recent ultrafast experiments have implicated that intrachain base-stacking rather than base-pairing mediate the fate and transport of photoexcited species in DNA chains. Here use an $SU(2)\otimes SU(2)$ lattice model which incorporates both intrachain and interchain electronic interactions to study the quantum mechanical evolution of an initial ...
arxiv  

LEAD-ADENOSINE TRIPHOSPHATE COMPLEXES IN ADENOSINE TRIPHOSPHATASE HISTOCHEMISTRY [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 1969
Chelation of lead by adenosine triphosphate (ATP) and its consequences for adenosine triphosphatase histochemistry were examined. The formation constant of lead-ATP chelates was found by two methods to be 4.6-4.7 x 104. The characteristics of enzyme inhibition by lead were consistent with the predicted effects of lead-ATP chelation.
openaire   +3 more sources

Protein Kinase C α Associates with Phospholipase D1 and Enhances Basal Phospholipase D Activity in a Protein Phosphorylation-Independent Manner in Human Melanoma Cells [PDF]

open access: yes, 2003
It is well known that phospholipase D plays a crucial part in the signal transduction of many types of cells, and is activated by protein kinase C α when cells are stimulated.
Goto, Akinobu   +5 more
core   +1 more source

Wnt signalosomes: What we know that we do not know

open access: yesBioEssays, Volume 47, Issue 2, February 2025.
Wnt signaling occurs through a “signalosome” receptor complex, driven by oligomerization of the adaptor, Disheveled (Dvl). Both endocytosis and condensate formation have been proposed to mediate signalosome formation. Under pathological conditions, signalosomes may form in a Wnt ligand‐independent manner.
Heather Hartmann   +6 more
wiley   +1 more source

Large-Scale Discovery of ERK2 Substrates Identifies ERK-Mediated Transcriptional Regulation by ETV3 [PDF]

open access: yes, 2011
The mitogen-activated protein kinase (MAPK) extracellular signal–regulated kinase 2 (ERK2) is ubiquitously expressed in mammalian tissues and is involved in a wide range of biological processes.
Carlson, Scott M.   +6 more
core   +1 more source

The Mysterious World of Non‐Canonical Caps – What We Know and Why We Need New Sequencing Techniques

open access: yesChemBioChem, Volume 26, Issue 3, February 1, 2025.
This review describes sophisticated methodologies such as LC–MS that enabled the identification of 5’ non‐canonical RNA caps and also surveys so far developed sequencing methods, evaluating their advantages and disadvantages. It emphasizes the need for developing new, reliable sequencing techniques to identify RNA types with non‐canonical caps enabling
Flaminia Mancini, Hana Cahova
wiley   +1 more source

Frenkel Exciton Model of Ultrafast Excited State Dynamics in AT DNA Double Helices [PDF]

open access: yesJ. Photochem. and Photobiol. A 190, 328-334 (2007), 2006
Recent ultrafast experiments have implicated intrachain base-stacking rather than base-pairing as the crucial factor in determining the fate and transport of photoexcited species in DNA chains. An important issue that has emerged concerns whether or not a Frenkel excitons is sufficient one needs charge-transfer states to fully account for the dynamics.
arxiv  

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