Results 21 to 30 of about 187,970 (266)
The Role of 8-Oxoguanine DNA Glycosylase-1 in Inflammation [PDF]
, 2017 Many, if not all, environmental pollutants/chemicals and infectious agents increase intracellular levels of reactive oxygen species (ROS) at the site of exposure.
Aguilera-Aguirre, Leopoldo +8 more
core +4 more sources
AAA+ ATPases in Protein Degradation: Structures, Functions and Mechanisms
Biomolecules, 2020 Adenosine triphosphatases (ATPases) associated with a variety of cellular activities (AAA+), the hexameric ring-shaped motor complexes located in all ATP-driven proteolytic machines, are involved in many cellular processes.
Shuwen Zhang, Youdong Mao
doaj +1 more source
Protective effect of rutin in comparison to silymarin against induced hepatotoxicity in rats [PDF]
Veterinary World, 2017 Aim: The aim of this study is to evaluate the hepatoprotective effect of rutin (RTN) in comparison to silymarin (SLM) against acetaminophen (APAP)-induced hepatotoxicity in rats. Materials and Methods: Male Wistar albino rats (n=24) of 3 months age were
M. Kasi Reddy +5 more
doaj +1 more source
Altered chemomechanical coupling causes impaired motility of the kinesin-4 motors KIF27 and KIF7. [PDF]
, 2018 Kinesin-4 motors play important roles in cell division, microtubule organization, and signaling. Understanding how motors perform their functions requires an understanding of their mechanochemical and motility properties.
Blasius, T Lynne +7 more
core +2 more sources
Purification and cryoelectron microscopy structure determination of human V-ATPase
STAR Protocols, 2021 Summary: Vesicular- or vacuolar-type adenosine triphosphatases (V-ATPases) are multi-component, ATP-driven proton pumps, which play important roles in many physiological processes by acidifying intracellular vesicles, organelles, and the extracellular ...
Longfei Wang +3 more
doaj
Asian Pacific Journal of Tropical Biomedicine, 2019 Objective: To assess the protective effect of galangin on membrane bound enzymes in rats with streptozotocin-induced diabetes. Methods: A single low dose of streptozotocin was injected to adult male albino rats to induce hyperglycemia. Galangin (8 mg/kg)
Amal A Aloud +4 more
doaj +1 more source
The Nobel Prize in Chemistry 2004: 'ubiquitous' quality control of life [PDF]
, 2005 The Nobel Prize in Chem. for 2004 is shared by Aaron Ciechanover, Avram Hershko and Irwin Rose, who made fundamental discoveries concerning how cells regulate the breakdown of cellular proteins with extreme specificity.
Karigar, C.S., Siddalinga Murthy, K.R.
core +1 more source
In Favor of Establishment: Regulation of Chromatid Cohesion in Plants
Frontiers in Plant Science, 2017 In eukaryotic organisms, the correct regulation of sister chromatid cohesion, whereby sister chromatids are paired and held together, is essential for accurate segregation of the sister chromatids and homologous chromosomes into daughter cells during ...
Pablo Bolaños-Villegas +4 more
doaj +1 more source
From the cell membrane to the nucleus: unearthing transport mechanisms for Dynein [PDF]
, 2012 Mutations in the motor protein cytoplasmic dynein have been found to cause Charcot-Marie-Tooth disease, spinal muscular atrophy, and severe intellectual disabilities in humans. In mouse models, neurodegeneration is observed.
A. Friedman +53 more
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Adenosine triphosphatases of rat pancreatic islets: comparison with those of rat kidney.
Journal of Clinical Investigation, 1978 Electrolyte fluxes are fundamental to normal endocrine pancreatic function. Adenosine triphosphatases (ATPases) are enzyme systems believed to modulate electrolyte movements across membranes in a number of cell types. This study was undertaken to measure
S. Levin, B. Kasson, J. Driessen
semanticscholar +1 more source