Altered chemomechanical coupling causes impaired motility of the kinesin-4 motors KIF27 and KIF7. [PDF]
Kinesin-4 motors play important roles in cell division, microtubule organization, and signaling. Understanding how motors perform their functions requires an understanding of their mechanochemical and motility properties.
Blasius, T Lynne +7 more
core +2 more sources
Protective effect of rutin in comparison to silymarin against induced hepatotoxicity in rats [PDF]
Aim: The aim of this study is to evaluate the hepatoprotective effect of rutin (RTN) in comparison to silymarin (SLM) against acetaminophen (APAP)-induced hepatotoxicity in rats. Materials and Methods: Male Wistar albino rats (n=24) of 3 months age were
M. Kasi Reddy +5 more
doaj +1 more source
Objective: To assess the protective effect of galangin on membrane bound enzymes in rats with streptozotocin-induced diabetes. Methods: A single low dose of streptozotocin was injected to adult male albino rats to induce hyperglycemia. Galangin (8 mg/kg)
Amal A Aloud +4 more
doaj +1 more source
The phytochemical composition of Melia volkensii and its potential for insect pest management [PDF]
Due to potential health and environmental risks of synthetic pesticides, coupled with their non-selectivity and pest resistance, there has been increasing demand for safer and biodegradable alternatives for insect pest management.
Backx, Simon +9 more
core +2 more sources
ATP11C mutation is responsible for the defect in phosphatidylserine uptake in UPS-1 cells
Type IV P-type ATPases (P4-ATPases) translocate phospholipids from the exoplasmic to the cytoplasmic leaflets of cellular membranes. We and others previously showed that ATP11C, a member of the P4-ATPases, translocates phosphatidylserine (PS) at the ...
Naoto Takada +4 more
doaj +1 more source
Adenosine Triphosphatase Activity in Chloroplasts. [PDF]
J.S.C. Wessels +4 more
openalex +3 more sources
The Nobel Prize in Chemistry 2004: 'ubiquitous' quality control of life [PDF]
The Nobel Prize in Chem. for 2004 is shared by Aaron Ciechanover, Avram Hershko and Irwin Rose, who made fundamental discoveries concerning how cells regulate the breakdown of cellular proteins with extreme specificity.
Karigar, C.S., Siddalinga Murthy, K.R.
core +1 more source
In Favor of Establishment: Regulation of Chromatid Cohesion in Plants
In eukaryotic organisms, the correct regulation of sister chromatid cohesion, whereby sister chromatids are paired and held together, is essential for accurate segregation of the sister chromatids and homologous chromosomes into daughter cells during ...
Pablo Bolaños-Villegas +4 more
doaj +1 more source
From the cell membrane to the nucleus: unearthing transport mechanisms for Dynein [PDF]
Mutations in the motor protein cytoplasmic dynein have been found to cause Charcot-Marie-Tooth disease, spinal muscular atrophy, and severe intellectual disabilities in humans. In mouse models, neurodegeneration is observed.
A. Friedman +53 more
core +1 more source
Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity
Newly-formed synaptic vesicles (SVs) are rapidly acidified by vacuolar adenosine triphosphatases (vATPases), generating a proton electrochemical gradient that drives neurotransmitter loading.
Zohreh Farsi +8 more
doaj +1 more source

