Results 101 to 110 of about 353,372 (343)

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway

open access: yesAdvanced Science, EarlyView.
A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi   +8 more
wiley   +1 more source

Nanoparticle‐Modified Nanofibers Induce Ferroptosis and Stimulate Antitumor Immunity for Melanoma Therapy

open access: yesAdvanced Science, EarlyView.
This study presents a nanoparticle‐embedded nanofiber (5F/STFM/R‐ES) to inhibit melanoma growth and reduce the risk of metastasis and recurrence. The drug delivery system induces ferroptosis and potentiates immunotherapy through resiquimod (R848) and Fe/Mn‐based metal‐polyphenol networks (TFM).
Mingyang Li   +10 more
wiley   +1 more source

Increased NTPDase Activity in Lymphocytes during Experimental Sepsis

open access: yesThe Scientific World Journal, 2012
We investigated in rats induced to sepsis the activity of ectonucleoside triphosphate diphosphohydrolase (NTPDase; CD39; E.C. 3.6.1.5), an enzyme involved in the modulation of immune responses.
Claudia de Mello Bertoncheli   +11 more
doaj   +1 more source

Alterations in adenosine triphosphate and energy charge in cultured endothelial and P388D1 cells after oxidant injury. [PDF]

open access: bronze, 1985
Roger G. Spragg   +4 more
openalex   +1 more source

Global Evidence of the Unimodal Response of Ecosystem Respiration to Soil Moisture

open access: yesAdvanced Science, EarlyView.
Using global eddy covariance observations and a field experiment, this paper provides compelling evidence for the widespread unimodal relationship between soil moisture and ecosystem respiration and its water adaptation. Such knowledge facilitates understanding of soil moisture in affecting respiratory carbon emissions and has the potential to improve ...
Jinlong Peng   +9 more
wiley   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

open access: yesAdvanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao   +4 more
wiley   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

open access: yesAdvanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou   +9 more
wiley   +1 more source

Effect of Specific Spoilage Organisms on the Degradation of ATP-Related Compounds in Vacuum-Packed Refrigerated Large Yellow Croaker (Larimichthys crocea)

open access: yesFoods
This study examined the spoilage potential of specific spoilage organisms on the degradation of adenosine triphosphate (ATP)-related compounds in vacuum-packed refrigerated large yellow croaker.
Bohan Chen   +4 more
doaj   +1 more source

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