Results 131 to 140 of about 353,372 (343)

Trimetallic Nanozyme‐Embedded Smart Hydrogel Enables NIR‐Controlled Bacterial Killing and Oxidative Stress Alleviation

open access: yesAdvanced Science, EarlyView.
A microenvironment‐responsive hydrogel is developed incorporating polymyxin B‐modified AuMnCu nanozymes and dual drugs (tannic acid and tobramycin). At infection sites, it generates ROS, releases drugs responsively, and enhances mild photothermal action to disrupt bacterial redox balance.
Zehui Xiao   +5 more
wiley   +1 more source

Systemic Adenosine Triphosphate Impairs Neutrophil Chemotaxis and Host Defense in Sepsis

open access: yesCritical Care Medicine, 2017
Xiaoou Li   +7 more
semanticscholar   +1 more source

Magnetically‐Induced Suppression of Oxidative Stress Prevents Venous Thrombosis

open access: yesAdvanced Science, EarlyView.
Venous thromboembolism (VTE) remains a leading cause of cardiovascular mortality. This study demonstrates that static magnetic fields (SMF) offer a novel non‐pharmacological intervention against VTE by mitigating endothelial oxidative stress. Mechanistically, SMF elevates intracellular Ca2+, boosts ATP production, and suppresses NOX4‐mediated ROS ...
Nana Zhang   +12 more
wiley   +1 more source

ACYL ADENYLATES: THE INTERACTION OF ADENOSINE TRIPHOSPHATE AND l-METHIONINE

open access: hybrid, 1956
Paul Berg   +1 more
openalex   +1 more source

Protective Effect of Adenosine Triphosphate against 5-Fluorouracil-Induced Oxidative Ovarian Damage in vivo [PDF]

open access: gold, 2023
Mehmet Özer   +8 more
openalex   +1 more source

Immunometabolic Rewiring of Dendritic Cells to Overcome Glutamine‐Driven Immune Suppression in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
T26 is an immunometabolic prodrug that modulates colorectal cancer cells. It blocks glutamine metabolism and enhances STING signaling, which promotes the release of reprogrammed extracellular vesicles. These vesicles drive dendritic cell maturation and CD8⁺ T cell activation, thereby strengthening antitumor immunity and improving the effectiveness of ...
Bingjie Zhang   +13 more
wiley   +1 more source

Ir(III) Complexes Convert Cold to Hot Tumors via Ferroptosis/Necroptosis‐Driven Immunogenic Cell Death and Photosensitized CD47 Downregulation

open access: yesAdvanced Science, EarlyView.
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu   +8 more
wiley   +1 more source

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