Results 251 to 260 of about 474,757 (353)

Echocardiographic Stress Test with Adenosine Triphosphate: Optimization of the Algorithm

open access: hybrid, 2019
N. J. Nelasov   +7 more
openalex   +2 more sources

Fostamatinib and the risk of acute aortic dissection in immune thrombocytopenia

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Immune thrombocytopenia (ITP) is a rare autoimmune disorder characterized by platelet destruction. While most patients respond to first‐ or second‐line therapies, a small subset is multirefractory. Fostamatinib, an oral spleen tyrosine kinase (SYK) inhibitor, is a therapeutic option in these cases.
Paul Dalmas   +7 more
wiley   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis   +5 more
wiley   +1 more source

Coming to Terms: The Mechanisms of Overplus and Luxury Phosphorus Uptake for Polyphosphate Storage in Microalgae and Yeast

open access: yesBiotechnology and Bioengineering, EarlyView.
Plouviez et al. give a perspective on the terminology used for describing the mechanisms of polyphosphate accumulation in microalgae and yeast. Their differentiation of mechanisms is based on environmental P availability, polyP chemistry, genetics, or cellular function as described in recent literature.
Maxence Plouviez   +7 more
wiley   +1 more source

Adenosine triphosphate utilization rates and metabolic pool sizes in intact cells measured by transfer of 18O from water

open access: bronze, 1989
Stevan M. Dawis   +5 more
openalex   +1 more source

Intracellular self‐assembled nanoneedles for efficient lysosomal escape and CRISPR/Cas9 mediated gene editing

open access: yesBMEMat, EarlyView.
PlaMnB was formed by cytolysin A‐tumor homing peptides (THP)‐modified bacterial membranes encapsulating the clustered regularly interspaced short palindromic repeat/CRISPR‐associated protein (CRISPR/Cas9) plasmid and manganese dioxide. THP‐containing bacterial membrane enhances PlaMnB vascular permeability and tumor targeting, and after cellular ...
Chen Zhang   +9 more
wiley   +1 more source

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