Results 181 to 190 of about 314,751 (339)
Harvesting AAV by tangential flow filtration using reverse asymmetric membranes
Biotechnology Progress, EarlyView.Abstract Efficient bioreactor clarification for harvesting virus particles is often challenging. Tangential flow filtration is attractive as it can be easily adapted for batch and perfusion operations. Here the feasibility of using reverse asymmetric hollow fiber membranes, where the more open support structure faces the feed stream, has been ...
Xiaolei Hao +5 more
wiley +1 more source
Capturing and concentrating adenovirus using magnetic anionic nanobeads
International Journal of Nanomedicine, 2016 Akikazu Sakudo,1 Koichi Baba,2 Kazuyoshi Ikuta1,31Department of Virology, Research Institute for Microbial Diseases, Osaka University, Yamadaoka, Suita, Osaka, Japan; 2Baba Pediatric Clinic, Kadoma, Osaka, Japan; 3Kanonji Institute, The Research ...
Sakudo A, Baba K, Ikuta K
doaj
Mechanism and role of regulated cell death in tumor immunity and immunotherapy
Cancer Communications, EarlyView.Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu +4 more
wiley +1 more source
LOXL2 in anabolic response to chondrodysplasia mice progressive TMJ and knee osteoarthritis [PDF]
, 2019 Osteoarthritis (OA) is a degenerative joint disease that affects an estimated 9.6 % of men and 18 % of women over 60 years of age. However, there is no chondroprotective agent that is approved for clinical application.
Alsaqer, Saqer
core
Developmental Dynamics, EarlyView.Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff +6 more
wiley +1 more source
Exploration, EarlyView.Asiaticoside (AS) has known anti‐inflammatory effects in diabetic wounds, but the underlying mechanisms are still unclear. In this study, we reveal that AS alleviates inflammation in diabetic wounds by activating ferroptosis of M1 macrophages, which is attributed to the downregulation of ferroportin 1 and ferritinophagy‐induced degradation of ferritin ...
Shengnan Cui +13 more
wiley +1 more source
Vaccination of man with attentuated live adenovirus
, 1960 Griselda Hitchock +2 more
openalex +1 more source
Neutralizing, Hemagglutination-Inhibiting and Group Complement-Fixing Antibody Responses in Human Adenovirus Infections [PDF]
, 1966 Nathalie J. Schmidt +2 more
openalex +1 more source
Targeting NAT10 Inhibits Hepatocarcinogenesis via ac4C‐Mediated SMAD3 mRNA Stability
Exploration, EarlyView.This study demonstrates that elevated N‐acetyltransferase 10 (NAT10) expression stabilizes SMAD3 mRNA through ac4C modification, promoting the progression of hepatocellular carcinoma (HCC). NAT10 also activates the TGF‐β signaling pathway, facilitating epithelial‐to‐mesenchymal transition and inhibiting anoikis. Furthermore, the authors develop a small‐
Yigan Zhang +16 more
wiley +1 more source