Results 21 to 30 of about 314,751 (339)

Retrospective study of adenovirus in autopsied pulmonary tissue of pediatric fatal pneumonia in South China

BMC Infectious Diseases, 2008
Background Adenovirus are the important pathogen of pediatric severe pneumonia. The aim of this study is to analyze the infection, subtype and distribution of adenovirus in autopsied pulmonary tissue of fatal pneumonia in infants and children, and the ...
Gong Si-Tang, Xia Jian-Qing, Lu Jun-Peng, Xia Hui-Min, Wang Feng-Hua, Zeng Qi-Yi, Ou Zhi-Ying, Deng Li, Zhang Jian-Tao, Zhou Rong   +9 more
doaj   +1 more source

AAV production in stable packaging cells requires expression of adenovirus 22/33K protein to allow episomal amplification of integrated rep/cap genes

Scientific Reports, 2023
Efficient manufacture of recombinant adeno-associated virus (rAAV) vectors for gene therapy remains challenging. Packaging cell lines containing stable integration of the AAV rep/cap genes have been explored, however rAAV production needs to be induced ...
Weiheng Su, Leonard W. Seymour, Ryan Cawood   +2 more
doaj   +1 more source

Transferrinfection. A Highly Efficient Way to Express Gene Constructs in Eukaryotic Cells [PDF]

, 1992
No abstract ...
Atherton, Atherton, Chardonnet, CHRISTIAN PLANK, Cotten, Cotten, Cotten, Curiel, Curiel, DAVID T. CURIEL, Davidson, Day, ERNST WAGNER, Folk, Jones, Krol, KURT ZATLOUKAL, Lim, MATT COTTEN, MAX L. BIRNSTIEL, Mol, Pastan, PETER STEINLEIN, Powell, Sambrook, Sipe, Spiess, STEPHEN PHILLIPS, Stout, Stryer, Wagner, Wagner, Wharton, Wu, Wu, Zenke   +35 more
core   +1 more source

Development of novel adenoviral vectors to overcome challenges observed with HAdV-5 based constructs [PDF]

, 2011
Recombinant vectors based on human adenovirus serotype 5 (HAdV-5) have been extensively studied in pre-clinical models and clinical trials over the last two decades.
Julio Alonso-Padilla, Tibor Papp, Győző L Kaján, Mária Benkő, Menzo Havenga, Angelique Lemckert, Balázs Harrach, Andrew H Baker, Harrach, Benkő, Liu, Reddy, Benevento, Reddy, Rux, Bergelson, Wickham, Wolfrum, Arnberg, Burckhardt, Vectors used in gene therapy clinical trials., Appaiahgari, Pearson, Wilson, Chorny, Van Kampen, George, Ranki, Hendrickx, Ilan, Schaack, Aldhamen, Machitani, Appledorn, Perreau, Minamitani, Khare, Lyons, Carlisle, Seiradake, Xu, Khare, Qiu, Waddington, Kalyuzhniy, Vigant, Alba, Jonsson, Lenman, Doronin, Xu, Eichholz, Ganesan, Alemany, Piccolo, Mocanu, Piccolo, Khare, Xu, Lasaro, Zak, Zhang, Barouch, Bradley, Roberts, Gall, Fausther-Bovendo, Sumida, Miyazawa, Teigler, Smith, Molinier-Frenkel, Heemskerk, Hutnick, Tang, Olive, Leen, Joshi, Osada, Perreau, Seregin, Seregin, Fontanellas, Cerullo, Brunetti-Pierri, Seregin, Farrow, McConnell, Belousova, Seregin, Capasso, Green, Doronin, Kreppel, Matsui, Suzuki-Kouyama, Prill, Krasnykh, Zabner, Havenga, Lecollinet, Coughlan, Granio, Parker, Guse, Smith, Nicol, Bruder, Bruder, Baden, Coughlan, Mück-Häusl, Bi, Abbink, Abbink, Mastrangeli, Abrahamsen, Brough, Stone, Sirena, Stone, Seshidhar Reddy, Hemminki, Creech, Vogels, Kuhn, Di, Havenga, Kahl, Vogels, Lemckert, Teigler, Tameris, Ouédraogo, Keefer, Baden, Gilbert, Baden, Zahn, Johnson, Dakin, Alexander, Alexander, Gurwith, Lemiale, Jarecki-Khan, Saderi, Ko, Bangari, Ayalew, Hammond, Tuboly, Fischer, Hu, Greenall, Brake, Lopez-Gordo, Kremer, Soudais, Soudais, Silva, Puig, Fernandes, Tandon, Bangari, Nguyen, Lenaerts, Ying, van Olphen, Zakhartchouk, Cauthen, Reddy, Reddy, Li, Lenaerts, Sharma, Sharma, Roy, Cohen, Xiang, Quinn, Farina, Roy, Colloca, Barnes, O'Hara, Antrobus, Stanley, Tan, Michou, Ojkic, Sheppard, Corredor, Cherenova, Shashkova, Logunov, Both, Xu, Khatri, Hofmann, Löser, Both, Martiniello-Wilks, Tang, Fraser, Bridgeman, Doszpoly, Cortés-Hinojosa, Wigand, Kajon, Guy, Benkö, Lu, Günes, Wellehan, Phan   +215 more
core   +4 more sources

Adenovirus serotype 7 associated with a severe lower respiratory tract disease outbreak in infants in Shaanxi Province, China

Virology Journal, 2011
Background Pneumonia caused by adenovirus infection is usually severe especially with adenovirus serotype 7 commonly associated with lower respiratory tract disease outbreaks.
Xu Wenbo, Wang Li, Tan Xiaojuan, Tang Liuying   +3 more
doaj   +1 more source

Encounters with adenovirus [PDF]

Upsala Journal of Medical Sciences, 2019
In this paper I describe aspects of work on the human adenoviruses in which my laboratory has participated. It consists of two sections-one historic dealing with work performed in the previous century, and one dealing with the application of 'omics' technologies to understand how adenovirus-infected cells become reprogrammed to benefit virus ...
openaire   +3 more sources

Gene Delivery by Subconjunctival Injection of Adenovirus in Rats: A Study of Local Distribution, Transgene Duration and Safety. [PDF]

PLoS ONE, 2015
Subconjunctival injection is a minimally invasive route for gene delivery to ocular tissues, but has traditionally been limited to use in the cornea. The accurate ocular distribution of virus has not, however, been previously investigated.
Guei-Sheung Liu, Jiang-Hui Wang, Jia Hui Lee, Pei-Jhen Tsai, Han-En Tsai, Shwu-Jiuan Sheu, Hsiu-Chen Lin, Gregory J Dusting, Ming-Hong Tai, Youn-Shen Bee   +9 more
doaj   +1 more source

Adenovirus and miRNAs

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011
Adenovirus infection has a tremendous impact on the cellular silencing machinery. Adenoviruses express high amounts of non-coding virus associated (VA) RNAs able to saturate key factors of the RNA interference (RNAi) processing pathway, such as Exportin 5 and Dicer. Furthermore, a proportion of VA RNAs is cleaved by Dicer into viral microRNAs (mivaRNAs)
Puri Fortes, James D. Sutherland, Elena Carnero   +2 more
openaire   +3 more sources

Case report: a fatal case of disseminated adenovirus infection in a non-transplant adult haematology patient

BMC Infectious Diseases, 2018
Background We report a fatal case of disseminated adenovirus infection in a non-transplant haematology adult patient with chronic lymphocytic leukaemia who had completed combination chemoimmunotherapy a few months before developing respiratory symptoms ...
Michael Joffe, Simon D. Wagner, Julian W. Tang   +2 more
doaj   +1 more source

Adenoviruses associated with acute diarrhea in children in Beijing, China. [PDF]

PLoS ONE, 2014
Adenoviruses have been recognized as important causal pathogens of community-acquired diarrhea (CAD) among children, but their role in hospital-acquired diarrhea (HAD) is not well-understood.
Liying Liu, Yuan Qian, You Zhang, Jie Deng, Liping Jia, Huijin Dong   +5 more
doaj   +1 more source