Results 41 to 50 of about 314,751 (339)

An adenovirus agnogene

Nucleic Acids Research, 1982
The nucleotide sequence of a 550 base pairs long segment, located between map positions 21 and 22.5 in the adenovirus type 2 genome has been determined. S1 nuclease mapping and sequence analysis of cDNA copies of adenovirus mRNA demonstrated that the established sequence includes the i-leader which is spliced to the 5'-end of certain adenovirus mRNAs ...
Håkan Persson, Peter Aleström, Anders Virtanen, Michael G. Katze, Ulf Pettersson   +4 more
openaire   +4 more sources

Identification of Inhibitors and Drug Targets for Human Adenovirus Infections

Viruses, 2022
Adenoviruses can cause infections in people of all ages at all seasons of the year. Adenovirus infections cause mild to severe illnesses. Children, immunocompromised patients, or those with existing respiratory or cardiac disease are at higher risk ...
Minli Liu, Lefang Jiang, Weihua Cao, Jianguo Wu, Xulin Chen   +4 more
doaj   +1 more source

Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes [PDF]

, 2013
Death domain–associated protein (Daxx) cooperates with X-linked α-thalassaemia retardation syndrome protein (ATRX), a putative member of the sucrose non-fermentable 2 family of ATP-dependent chromatin-remodelling proteins, acting as the core ATPase ...
Andreas Mund, Badens, Baker, Berk, Berube, Blanchette, Carolin Bürck, Chatterjee, Cheng, Chinnadurai, Cuchet-Lourenco, Dallaire, Dellaire, Dobner, Drane, Everett, Flint, Frisch, Gibbons, Glass, Goldberg, Goldberg, Gostissa, Graham, Groitl, Gunther, Hancock, Harlow, Hassan, Hollenbach, Ishov, Ishov, Jin, Kahyo, Kindsmuller, Kindsmuller, Kindsmüller, Ko, Komatsu, Kosulin, Lewis, Lewis, Li, Lukashchuk, Lukashchuk, Mandy Glass, Marton, Matsumoto, Maul, McFarlane, Michaelson, Mitsudomi, Mund, Nevels, Nevins, Nevins, Niforou, Okuwaki, Orazio, Parks, Pelka, Peter Groitl, Peter Wimmer, Placek, Querido, Roger D. Everett, Ross, Rubenwolf, Sabrina Schreiner, Salomoni, Sarah Kinkley, Sarnow, Schreiner, Schreiner, Schreiner, Shenk, Si, Song, Stracker, Takahashi, Tang, Thomas Dobner, Torii, Täuber, Täuber, Ullman, White, Williams, Wilson, Wong, Wong, Xu, Xue   +92 more
core   +1 more source

Covalent decoration of adenovirus vector capsids with the carbohydrate epitope αGal does not improve vector immunogenicity, but allows to study the in vivo fate of adenovirus immunocomplexes. [PDF]

PLoS ONE, 2017
Adenovirus-based vectors are promising tools for genetic vaccination. However, several obstacles have to be overcome prior to a routine clinical application of adenovirus-based vectors as efficacious vectored vaccines.
Ramona F Kratzer, Sigrid Espenlaub, Andrea Hoffmeister, Matthias W Kron, Florian Kreppel   +4 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Emerging viral respiratory tract infections—environmental risk factors and transmission [PDF]

, 2014
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Charrel, Remi N., Gautret, Philippe, Gray, Gregory C., Memish, Ziad A., Odezulu, Nnanyelugo G., Zumla, Alimuddin   +6 more
core   +1 more source

A New Bovine Adenovirus Related to Human Adenovirus.

Experimental Biology and Medicine, 1960
SummaryA second bovine adenovirus has been isolated. The virus is antigenically similar to a human virus as determined by 1) neutralization with human gamma globulin and human adult sera, and 2) possession of a complement fixing antigen similar to that of the human adenovirus. The related type of human adenovirus remains unknown.
Joseph Zellat, Thomas C. Michaelson, Morton Klein   +2 more
openaire   +3 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Evolution and diversity of human adenoviruses isolated from patients with keratoconjunctivitis

Iranian Journal of Microbiology, 2022
Background and Objectives: Human adenovirus type 8 is a highly contagious eye disease and is considered as the most common epidemic keratoconjunctivitis worldwide.
Chiman Karami, Kamyar Mazloum Jalali, Shahram Jalilian, Gholamreza Khataminia, Somayeh Biparva Haghighi, Mohammad Karimi Babaahmadi, Reza Taherkhani, Manoochehr Makvandi   +7 more
doaj  

Hypoxia-induced expression of zinc finger protein A20 inhibits apoptosis and attenuates inflammation in nucleus pulposus cells

陆军军医大学学报, 2023
Objective To explore the effect and mechanism of zinc finger protein A20 in the nucleus pulposus cells of intervertebral disc with hypoxic conditions.
GUO Shuaichi, LIU Hao, HAN Zhenghan, LIU Wenjun, LIU Bo   +4 more
doaj   +1 more source